Abstract: A system for positioning a medical device with respect to at least one target zone of a patient. The system having a mount for a medical module, and a positioning device configured to move the mount with respect to the target zone. The system further having an imaging means, configured to obtain imaging data of at least one landmark arranged in a predefined relationship to the target zone. The system further having a computational system which includes an input interface for receiving the imaging data. The computational system further has an output interface which outputs data for controlling movement of the positioning device. The computational system is configured to determine a position of the landmark based on the imaging data. The computational system is further configured to control the position of the positioning device with respect to the target zone based on the determined position of the landmark.