Abstract: The present invention provides a compound having a Pim-1 inhibitory activity. The present invention provides a compound of Formula [I] or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing the same, and a pharmaceutical use thereof, and the like. wherein each symbol is as defined in the description.

Abstract: Information storage mediums such as video discs and digital audio discs are fabricated by extruding a mass of electrically conductive synthetic resin into a block assembly composed of a pair of separable blocks in which the mass is molded into a cake that is then carried by one of the blocks as separated into a press in which the cake is pressed into an information storage medium or disc blank. The blank is transferred into a trimmer for trimming an overflow off the disc blank as an annular scrap, which is in turn chopped by a chopper into pieces for reuse. a disc from which the scrap has been removed is fed to a hot stamping machine in which an identification foil piece is attached with heat to the disc. The disc with the foil piece stamped thereon is punched to form a central hole by a punching machine.

Abstract: Information storage mediums such as video discs and digital audio discs are fabricated by extruding a mass of electrically conductive synthetic resin into a block assembly composed of a pair of separable blocks in which the mass is molded into a cake that is then carried by one of the blocks as separated into a press in which the cake is pressed into an information storage medium or disc blank. The blank is transferred into a trimmer for trimming an overflow off the disc blank as an annular scrap, which is in turn chopped by a chopper into pieces for reuse. A disc from which the scrap has been removed is fed to a hot stamping machine in which an identification foil piece is attached with heat to the disc. The disc with the foil piece stamped thereon is punched to form a central hole by a punching machine.