Abstract: A mining riser pipe is extended from above water toward a water bottom containing water bottom resources, and a lower portion of an insertion pipe connected to a lower portion of the mining riser pipe is inserted into the water bottom. A liquid is supplied into the insertion pipe and a rotation shaft extends axially inside both of pipes is rotated to rotate stirring blades attached to a lower portion of the rotation shaft inside the insertion pipe, thereby drilling and dissolving mud S inside the insertion pipe into a slurry form is raised to an upper portion of the insertion pipe by a stirring flow generated by the rotation of the stirring blades, and the raised mud is lifted above the water through the mining riser pipe by lifting force.

Abstract: An acquisition unit 104 acquires from a server a status of a friend user. A menu image generation unit 110 generates a menu image including an icon. A user image placement unit 116 places, on the periphery of the icon, images of friend users whose statuses acquired by the acquisition unit 104 are related to the icon. The icon is an icon representing content, and the user image placement unit 116 places, on the periphery of the icon, an image of a friend user currently performing the content.

Abstract: Administration of a decoy, i.e. a compound which specifically antagonizes the nucleic acid domain to which NF-?B is bound, is effective in the treatment and prevention of diseases caused by the transcriptional regulatory factor NF-?B, such as ischemic diseases, inflammatory diseases, autoimmune diseases, cancer metastasis and invasion, and cachexia.

Abstract: Administration of a decoy, i.e. a compound which specifically antagonizes the nucleic acid domain to which NF-?B is bound, is effective in the treatment and prevention of diseases caused by the transcriptional regulatory factor NF-?B, such as ischemic diseases, inflammatory diseases, autoimmune diseases, cancer metastasis and invasion, and cachexia.

Abstract: Administration of a decoy, i.e. a compound which specifically antagonizes the nucleic acid domain to which NF-&kgr;B is bound, is effective in the treatment and prevention of diseases caused by the transcriptional regulatory factor NF-&kgr;B, such as ischemic diseases, inflammatory diseases, autoimmune diseases, cancer metastasis and invasion, and cachexia.

Abstract: The invention provides a choleretic composition, a bile acid secretion-promoting composition and a therapeutic composition for cholestasis each comprising insulin-like growth factor I or an analog thereof as well as a method of promoting secretion of bile which comprises administering insulin-like growth factor I or an analog thereof, a method of promoting secretion of bile acids, and a method for therapy of cholestasis in mammals.

Abstract: The invention provides a composition for improving an action of an immunosuppressant, comprising insulin-like growth factor I or its analog as an active ingredient.

Abstract: The invention provides a composition for improving an action of an immunosuppressant, comprising insulin-like growth factor I or its analog as an active ingredient.

Abstract: Administration of a decoy, i.e. a compound which specifically antagonizes the nucleic acid domain to which NF-&kgr;B is bound, is effective in the treatment and prevention of diseases caused by the transcriptional regulatory factor NF-&kgr;B, such as ischemic diseases, inflammatory diseases, autoimmune diseases, cancer metastasis and invasion, and cachexia.

Abstract: Administration of a decoy, i.e. a compound which specifically antagonizes the nucleic acid domain to which NF-&kgr;B is bound, is effective in the treatment and prevention of diseases caused by the transcriptional regulatory factor NF-&kgr;B, such as ischemic diseases, inflammatory diseases, autoimmune diseases, cancer metastasis and invasion, and cachexia.