Patents by Inventor Ikuroh Ohsawa

Ikuroh Ohsawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10160949
    Abstract: The present invention addresses the problem of providing an agent for improving sperm-motility, in particular, an agent for improving forward-sperm-motility, for use on reduced-motility sperm in male infertility treatment. Prepared is a gaseous agent for improving sperm-motility consisting of a gas that contains hydrogen molecules in the amount of 1% (v/v) or higher, for example, a gas that contains hydrogen molecules in an amount of between 45 and 55% (v/v), or a liquid agent for improving sperm-motility consisting of a liquid such as physiological saline, a culture solution, or a buffer solution containing hydrogen molecules in the amount of 1% or higher of the saturation solubility thereof, for example, a liquid in which hydrogen molecules have been dissolved by bubbling.
    Type: Grant
    Filed: October 30, 2014
    Date of Patent: December 25, 2018
    Assignees: Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
    Inventors: Naoki Yamashita, Kumiko Nakata, Ikuroh Ohsawa
  • Publication number: 20160281057
    Abstract: The present invention addresses the problem of providing an agent for improving sperm-motility, in particular, an agent for improving forward-sperm-motility, for use on reduced-motility sperm in male infertility treatment. Prepared is a gaseous agent for improving sperm-motility consisting of a gas that contains hydrogen molecules in the amount of 1% (v/v) or higher, for example, a gas that contains hydrogen molecules in an amount of between 45 and 55% (v/v), or a liquid agent for improving sperm-motility consisting of a liquid such as physiological saline, a culture solution, or a buffer solution containing hydrogen molecules in the amount of 1% or higher of the saturation solubility thereof, for example, a liquid in which hydrogen molecules have been dissolved by bubbling. The gaseous agent for improving sperm-motility can improve the motility of sperm by contacting hydrogen gas and either semen or a dilution thereof with each other in a gaseous phase.
    Type: Application
    Filed: October 30, 2014
    Publication date: September 29, 2016
    Inventors: Naoki Yamashita, Kumiko Nakata, Ikuroh Ohsawa
  • Patent number: 9050278
    Abstract: An object of the present invention is to provide a scavenger of in vivo harmful reactive oxygen species and/or free radicals, which is capable of effectively reducing the concentrations of in vivo reactive oxygen species and/or free radicals and exhibiting given effects such as the suppression of aging process, the prevention of geriatric or lifestyle-related disease, health promotion, and the inhibition of oxidative stress by virtue of this reduction in the concentrations of reactive oxygen species and/or free radicals. The scavenger of in vivo harmful reactive oxygen species and/or free radicals of the present invention comprises a liquid or gas comprising at least a hydrogen molecule. This medium may further comprise an oxygen molecule. Furthermore, this medium may comprise water or an aqueous solution or may be a gas. The scavenger of reactive oxygen species and/or free radicals can be used in the treatment or prevention of a disorder attributed to reactive oxygen species and/or free radicals.
    Type: Grant
    Filed: February 5, 2013
    Date of Patent: June 9, 2015
    Inventors: Shigeo Ohta, Wataru Murota, Ikuroh Ohsawa
  • Publication number: 20100291228
    Abstract: An object of the present invention is to provide a scavenger of in vivo harmful reactive oxygen species and/or free radicals, which is capable of effectively reducing the concentrations of in vivo reactive oxygen species and/or free radicals and exhibiting given effects such as the suppression of aging process, the prevention of geriatric or lifestyle-related disease, health promotion, and the inhibition of oxidative stress by virtue of this reduction in the concentrations of reactive oxygen species and/or free radicals. The scavenger of in vivo harmful reactive oxygen species and/or free radicals of the present invention comprises a liquid or gas comprising at least a hydrogen molecule. This medium may further comprise an oxygen molecule. Furthermore, this medium may comprise water or an aqueous solution or may be a gas. The scavenger of reactive oxygen species and/or free radicals can be used in the treatment or prevention of a disorder attributed to reactive oxygen species and/or free radicals.
    Type: Application
    Filed: August 2, 2010
    Publication date: November 18, 2010
    Inventors: Shigeo Ohta, Wataru Murota, Ikuroh Ohsawa
  • Publication number: 20090246290
    Abstract: According to the present invention, a lipid metabolism improving agent containing hydrogen molecules that is in a liquid or gas state is provided. The lipid metabolism improving agent of the present invention comprises a liquid or gas containing at least hydrogen molecules. It may comprise a medium containing oxygen molecules. Further, such medium may comprise water, an aqueous solution, or a gas. The lipid metabolism improving agent has effects of suppressing body fat accumulation, arteriosclerosis, and the like.
    Type: Application
    Filed: August 31, 2007
    Publication date: October 1, 2009
    Inventors: Shigeo Ohta, Wataru Murota, Ikuroh Ohsawa
  • Publication number: 20090035383
    Abstract: An object of the present invention is to provide a scavenger of in vivo harmful reactive oxygen species and/or free radicals, which is capable of effectively reducing the concentrations of in vivo reactive oxygen species and/or free radicals and exhibiting given effects such as the suppression of aging process, the prevention of geriatric or lifestyle-related disease, health promotion, and the inhibition of oxidative stress by virtue of this reduction in the concentrations of reactive oxygen species and/or free radicals. The scavenger of in vivo harmful reactive oxygen species and/or free radicals of the present invention comprises a liquid or gas comprising at least a hydrogen molecule. This medium may further comprise an oxygen molecule. Furthermore, this medium may comprise water or an aqueous solution or may be a gas. The scavenger of reactive oxygen species and/or free radicals can be used in the treatment or prevention of a disorder attributed to reactive oxygen species and/or free radicals.
    Type: Application
    Filed: August 18, 2006
    Publication date: February 5, 2009
    Inventors: Shigeo Ohta, Wataru Murota, Ikuroh Ohsawa
  • Patent number: 5871742
    Abstract: A polypeptide exhibiting the antigenicity of Mycoplasma gallisepticum, a fused polypeptide comprising the above polypeptide and, connected to the N-terminus thereof, a signal membrane anchor of a type II outer-membrane polypeptide of a virus that infects birds, or a polypeptide capable of reacting with a mycoplasma-immune serum or a mycoplasma-infected serum and exhibiting a substantially pure antigenecity, respectively having amino acid sequences of about 32 kDa, about 40 kDa, or about 70 kDa. The expression with a recombinant virus of a polypeptide modified to such an extent as to exhibit an antigenicity equivalent to that of any of the above polypeptides. The use of a recombinant virus as a live vaccine.
    Type: Grant
    Filed: September 25, 1995
    Date of Patent: February 16, 1999
    Assignees: Nippon Zeon Co., Ltd, Shionogi & Co., Ltd.
    Inventors: Shuji Saitoh, Setsuko Ohkawa, Sakiko Saeki, Ikuroh Ohsawa, Hirono Funato, Yoshikazu Iritani, Shigemi Aoyama, Kiyohito Takahashi