Patents by Inventor Ila Sircar

Ila Sircar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 2,2-dimethyl-5-phenoxypentanoic acid benzamides as anti-arteriosclerotic agents and method
    Patent number: 4413011
    Abstract: New substituted 2,2-dimethyl-5-phenoxypentanoic acid benzamides which are useful as anti-arteriosclerotic agents are disclosed. These compounds elevate the high density lipoprotein fraction of cholesterol, and also lower the low density lipoprotein fraction of cholesterol.
    Type: Grant
    Filed: February 26, 1981
    Date of Patent: November 1, 1983
    Assignee: Warner-Lambert Company
    Inventors: Ila Sircar, Ann Holmes
  • Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
    Patent number: 4404203
    Abstract: Substituted 6-phenyl-3(2H)-pyridazinone compounds are useful as cardiotonic agents.Said compounds cause a significant increase in myocardial contractility in the anesthetized dog. Said compounds are produced by reacting substituted benzoylpropionic acids with suitably substituted hydrazines to provide 6-phenyl-4,5-dihydro-3(2H)-pyridazinones which are dehydrogenated to the desired product.The intermediate 6-phenyl-4,5-dihydro-3(2H)-pyridazinones are themselves useful as cardiotonic agents.
    Type: Grant
    Filed: May 14, 1981
    Date of Patent: September 13, 1983
    Assignee: Warner-Lambert Company
    Inventor: Ila Sircar
  • [3,6-Pyridazinediylbis(thio)]bis-[2,2-dimethylalkanoic acids] and derivatives as anti-arteriosclerotic agents and method
    Patent number: 4397852
    Abstract: New substituted [3,6-pyridazinediylbis(thio)]bis-[2,2-dimethylalkanoic acids] and derivatives which are useful as anti-arteriosclerotic agents are disclosed. These compounds elevate the high density lipoprotein fraction of cholesterol, and also lower the low density lipoprotein fraction of cholesterol.
    Type: Grant
    Filed: December 18, 1981
    Date of Patent: August 9, 1983
    Assignee: Warner-Lambert Company
    Inventor: Ila Sircar
  • Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
    Patent number: 4397854
    Abstract: Substituted 6-phenyl-3(2H)-pyridazinone compounds are useful as cardiotonic agents.Said compounds cause a significant increase in myocardial contractility in the anesthetized dog. Said compounds are produced by reacting substituted .gamma.-oxobenzenebutanoic acids with suitably substituted hydrazines to provide 6-phenyl-4,5-dihydro-3(2H)-pyridazinones which are dehydrogenated to the desired product.The intermediate 6-phenyl-4,5-dihydro-3(2H)-pyridazinones are themselves useful as cardiotonic agents.
    Type: Grant
    Filed: November 30, 1981
    Date of Patent: August 9, 1983
    Assignee: Warner-Lambert Company
    Inventor: Ila Sircar
  • 4-(Substituted)-.alpha., .alpha.-dimethyl-1-piperazine pentanoic acids and derivatives as anti-arteriosclerotic agents and method
    Patent number: 4397855
    Abstract: New 4-(substituted-.alpha., .alpha.-dimethyl-1-piperazine pentanoic acids and derivatives which are useful as anti-arteriosclerotic agents are disclosed. These compounds elevate the high density lipoprotein fraction of cholesterol, and also lower the low density lipoprotein fraction of cholesterol.
    Type: Grant
    Filed: June 26, 1981
    Date of Patent: August 9, 1983
    Assignee: Warner-Lambert Company
    Inventor: Ila Sircar
  • Substituted 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones
    Patent number: 4353905
    Abstract: Substituted 4,5-dihydro-6-[4-(1H-imidazol-1-yl)-phenyl]-3(2H)-pyridazinone compounds and 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinone compounds and pharmaceutically acceptable salts thereof are useful as cardiotonic agents.Said compounds cause a significant increase in myocardial contractility in the anesthetized dog. Said compounds are produced by reacting substituted .gamma.-oxo-benzenebutanoic acids with suitably substituted hydrazines to provide 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones which are dehydrogenated to 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones.Both the intermediate 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and the 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones are useful as cardiotonic agents.
    Type: Grant
    Filed: September 17, 1981
    Date of Patent: October 12, 1982
    Assignee: Warner-Lambert Company
    Inventors: Ila Sircar, James A. Bristol
  • Anti-arteriosclerotic agents
    Patent number: 4351950
    Abstract: Novel substituted arylene compounds and methods for their preparation and use are disclosed. These new compounds are useful as anti-arteriosclerotic agents.
    Type: Grant
    Filed: January 2, 1980
    Date of Patent: September 28, 1982
    Assignee: Warner-Lambert Company
    Inventor: Ila Sircar