Patents by Inventor Ilana Harari

Ilana Harari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Shiga toxin B chain polypeptides and vaccine thereto
    Patent number: 5204097
    Abstract: The invention relates to a number of synthetic polypeptides which correspond to a part of the sequences of the Shiga B peptide chain. More specifically, the invention relates to polypeptides corresponding to the residues 5 to 18, 7 to 26, 13 to 26, and 19 to 29 of said B chain. The invention further relates to the conjugates of each of these with a suitable carrier and to polymers of each or these obtained by polymerization with a suitable polymerization agent: these can be used as effective vaccines which afford protection against Shiga toxin. Anti-peptide anti-sera are effective in neutralizing to a large extent the biological activity of Shiga toxin.
    Type: Grant
    Filed: June 9, 1989
    Date of Patent: April 20, 1993
    Assignee: Yeda Research and Development Company Limited
    Inventors: Ruth Arnon, Ilana Harari, Gerald T. Keusch, Arthur Donohue-Rolfe