Abstract: Method and system for non-invasive quantification of tissue perfusion obtainable by a destruction-reperfusion process that provide a signal representative of local agent concentration during reperfusion, by deriving at least one local tissue perfusion value. The system is configured to adjust or relate function of time with S-shape characteristics to the signal proportional to the local agent concentration during reperfusion, and making a correspondence between at least one value of at least one parameter of the function with S-shape characteristics with at least one local tissue perfusion value (such as mean velocity, mean transit time, mean flow, perfusion volume) or attribute (such as the blood flow pattern, flow distribution variance or skewness).

Abstract: A method for coding pixels or voxels of a digital or digitalized two dimensional or three dimensional image includes the steps of: providing a digital image in which each pixel or voxel is defined by a variable in a grey scale image, or by HSV or RGB values in a color image; generating a vector univocally associated to the target pixel or voxel and having components generated as a function of the values of the pixels or voxels in a window that includes the target pixel or voxel and neighboring pixels or voxels. The function of the values of the target pixel or voxel and of the pixels or voxels in the window corresponds to the characteristic parameters of the numerical matrix representing the pixels or voxels of the window or of a transformation of the numerical matrix.

Abstract: In a method for registering biomedical images such as at least a first and a second digital or digitalized image or set of cross-sectional images of the same object, within the first image or set of images a certain number of landmarks, so called features are individuated by selecting a certain number of pixels or voxels. The position of each pixel or voxel selected as a feature is tracked from the first to the second image or set of images by determining the optical flow vector from the first to the second image or set of images for each pixel or voxel selected as a feature. Registration of the first and second images or set of images is carried out by applying the inverse optical flow to the pixels or voxels of the second image or set of images.

Abstract: A method for coding pixels or voxels of a digital or digitalized two dimensional or three dimensional image, comprises the steps of: providing a digital image consisting in a two dimensional array of pixels or in a three dimensional array of voxels, each pixel or voxel being defined by at least one variable as its intensity in a grey scale image or the HSV (Hue, Saturation and Value) or the RGB values in a colour image; each pixel or voxel and for each target pixel or voxel a neighborhood being formed by a pixel or voxel windows comprising the said target pixel or voxel and a certain number of surrounding pixels or voxels for each target pixel or voxel generating a vector univocally associated to the said target pixel or voxel, the components of the said vectors being generated as a function of the values of the said target pixel or voxel and of each of the pixels or voxels of the said pixel or voxel window.

Abstract: Method and system for non-invasive quantification of tissue perfusion obtainable by a destruction-reperfusion process that provide a signal representative of local agent concentration during reperfusion, by deriving at least one local tissue perfusion value. The system comprises means for adjusting or relating a function of time with S-shape characteristics to the signal proportional to the local agent concentration during reperfusion, and making a correspondence between at least one value of at least one parameter of the function with S-shape characteristics with at least one local tissue perfusion value (such as mean velocity, mean transit time, mean flow, perfusion volume) or attribute (such as the blood flow pattern, flow distribution variance or skewness).