Patents by Inventor Ildiko M. Kovach

Ildiko M. Kovach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for temporarily inhibiting or deactivating serine hydrolase and adduct of serine hydrolase with a phosphonate or phosphate compound
    Patent number: 5314815
    Abstract: Phenacyl phosphonate adducts of serine hydrolases temporarily inhibit or inactivate the serine hydrolases. The serine hydrolases are activated by intramolecularly catalyzed dephosphonylation of the adduct over a period of time. Half-lives for dephosphonylation in the range of about 30 to 500 minutes have been observed at physiological pH's.
    Type: Grant
    Filed: March 4, 1992
    Date of Patent: May 24, 1994
    Assignee: The Catholic University of America
    Inventor: Ildiko M. Kovach
  • Temporary inactivation of serine hydrolases using nitrophenyl phenacyl phosphonates
    Patent number: 5281523
    Abstract: Phenacyl phosphonate adducts of serine hydrolases temporarily inactivate the hydrolases. The hydrolases are reactivated by intramolecularly catalyzed dephosphonylation of the adduct over a period of time. Half-lives for dephosphonylation in the range of about 30 to 500 minutes have been observed at physiological pH's.
    Type: Grant
    Filed: March 4, 1992
    Date of Patent: January 25, 1994
    Assignee: The Catholic University of America
    Inventor: Ildiko M. Kovach