Patents by Inventor Ildiko Mathe

Ildiko Mathe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-([1,4]benzodioxan-2-ylmethyl)-N-(3-chloro-1-propyl)-amine
    Patent number: 6248907
    Abstract: The invention relates to R-2-[3-([1,4]benzodioxan-2-ylmethylamino)-1-propyl]-3(2H)-pyridazinone of formula (1), and to S-2-[3-([1,4]benzodioxan-2-ylmethylamino)-1-propyl]-3(2H)-pyridazinone of formula (2), and to acid-addition salts thereof as well as pharmaceutical compositions containing these compounds. Furthermore, the invention relates to a process for the preparation of the above compounds. The new starting compounds of formulae (4) and (5) are also involved in the scope of the invention. The compounds according to the invention possess &agr;1- and &agr;2-adrenoceptor antagonistic effects and urogenital selectivity. Thus, they are useful for the treatment of the benign prostate hyperplasia.
    Type: Grant
    Filed: August 28, 2000
    Date of Patent: June 19, 2001
    Assignee: Gyogyszerkutato Intezet Kft.
    Inventors: Péter Mátyus, László Hársing, Marianne Tapfer née Karim, Judit Kosáry, Ágnes Papp née Behr, Antal Simay, Yemane Tilahun, Éva Tomori née Joszt, Edit Horváth, Katalin Horváth, Ildikó Varga, Erzsébet Zára née Kaczián, Margit Bidló née Iglóy, Alice Druga, György Rabloczky, Márta Varga, Egon Kárpáti, Endre Kasztreiner, István Király, Ildikó Máthé née Gyóry, György Máthé, László Sebestyén, Nándor Makk
  • N-benzoylamino acid derivatives, pharmaceutical compositions containing them and process of preparing same
    Patent number: 5854250
    Abstract: An N-benzoylamino acid compound of the formula (I), ##STR1## wherein R.sup.3 is an NR.sup.4 R.sup.5 group where R.sup.4 and R.sup.5 which are the same or different are selected from the group consisting of hydrogen, a hydroxyl group, a C.sub.1-12 alkyl group, a C.sub.1-4 alkyl group substituted by a hydroxyl group and a C.sub.1-4 alkyl group substituted by an amino group;R.sup.4 and R.sup.5 when taken together with the adjacent nitrogen form a substituted or unsubstituted 5- or 6-membered heterocyclic group, a 5- or 6-membered heterocyclic group containing an additional nitrogen atom, a 5- or 6-membered heterocyclic group containing an additional nitrogen atom and being substituted by an oxo group, a phenyl-substituted C.sub.1-4 alkyl group or C.sub.
    Type: Grant
    Filed: August 8, 1997
    Date of Patent: December 29, 1998
    Assignee: Gyogyszerkutato Intezet KFT
    Inventors: Peter Matyus, Erzsebet Zara, Lajos Farkas, Agnes Papp, Antal Simay, Lajos Toldy, Ferenc Andrasi, Katalin Goldschmidt, Eszter Hodula, Ildiko Mathe, Klara Sutka, Zsuzsanna Fittler, Valeria Vitkoczi, Laszlo Sebestyen, Istvan Sziraki, Marta Rusz, Eva Gal
  • N-benzoyl amino acid derivatives pharmaceutical compositions containing them and process for preparing same
    Patent number: 5705529
    Abstract: The invention relates to novel N-benzoylamino acid derivatives of the general formula (I), ##STR1## wherein R.sup.1 and R.sup.2, which are the same or different, stand for a hydroxyl group optionally bearing an acetyl group; or a C.sub.1-6 alkoxy group optionally substituted by a phenyl group;n means an integer from 2 to 15as well as their tautomers, racemates and optically active individual (pure) isomers or mixtures thereof and the salts of these compounds and pharmaceutical compositions containing these compounds.The invention relates also to a process for the preparation of compounds of the general formula (I).
    Type: Grant
    Filed: October 11, 1995
    Date of Patent: January 6, 1998
    Assignee: Gyogyszerkutato Intezet KFT
    Inventors: Peter Matyus, Erzsebet Zara, Lajos Farkas, Agnes Papp, Antal Simay, Lajos Toldy, Ferenc Andrasi, Katalin Goldschmidt, Eszter Hodula, Ildiko Mathe, Klara Sutka, Zsuzsanna Fittler, Valeria Vitkoczi, Laszlo Sebestyen, Istvan Sziraki, Marta Rusz, Eva Gal