Abstract: A composition that can be used to form an epoxy-based coating for use in wet environments, the coating exhibiting anti-fouling/foul-releasing properties, improved corrosion resistance, increased mechanical strength, or bending strength of at least 10 mm (relative to a control coating).

Abstract: A method of making drug-eluting regenerated silk fibroin particles using cryogranulation. The method has a first step of injecting a mixture into a super-cooled fluid, the mixture including regenerated silk fibroin and at least one medicament. A second step of incubating the drug-eluting particles in the super-cooled fluid to promote cryogelation may also be used. The size distribution, morphology, and cross-linking efficiency of the particles can depend on several controllable variable, such as starting concentrations of cross-linking agents and silk fibroin in the mixture, the injection pressure, and the temperature of the super-cooled fluid.