Patents by Inventor Ilia Davydov

Ilia Davydov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substrates of N-end rule ubiquitylation and methods for measuring the ubiquitylation of these substrate
    Patent number: 8530408
    Abstract: The present invention relates to methods, compositions, compounds and kits for detecting, measuring and modulating protein ubiquitylation via the N-end rule pathway and for identifying novel substrates, enzymes and modulators of N-end rule ubiquitylation. The present invention also relates to specific substrates of N-end rule ubiquitylation as well as activated fragments of these substrates, proteases that expose N-degrons in these substrates, ubiquitin ligases that ubiquitylate these substrates and inhibitors of the ubiquitylation of these substrates.
    Type: Grant
    Filed: October 27, 2009
    Date of Patent: September 10, 2013
    Assignee: Meso Scale Technologies LLC
    Inventors: Ilia Davydov, John H. Kenten, Hans Biebuyck, Pankaj Oberoi
  • DEAZAFLAVIN COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20100048593
    Abstract: The present invention features 5-deazaflavin compounds, pharmaceutical compositions of 5-deazaflavin compounds and methods of treating a patient suffering from cancer, the method comprising administering to a patient one or more 5-deazaflavin compounds of the invention.
    Type: Application
    Filed: February 23, 2009
    Publication date: February 25, 2010
    Applicants: Government of the US, as represented by the Secretary, Department of Health & Human Services, BioVeris Corporation
    Inventors: Allan M. Weissman, Karen H. Vousden, Jane P. Jensen, Yili Yang, Shengyun Fang, Douglas Woods, John H. Kenten, Ilia Davydov, Yassamin J. Safiran, Pankaj Oberoi
  • SUBSTRATES OF N-END RULE UBIQUITYLATION AND METHODS FOR MEASURING THE UBIQUITYLATION OF THESE SUBSTRATE
    Publication number: 20100048485
    Abstract: The present invention relates to methods, compositions, compounds and kits for detecting, measuring and modulating protein ubiquitylation via the N-end rule pathway and for identifying novel substrates, enzymes and modulators of N-end rule ubiquitylation. The present invention also relates to specific substrates of N-end rule ubiquitylation as well as activated fragments of these substrates, proteases that expose N-degrons in these substrates, ubiquitin ligases that ubiquitylate these substrates and inhibitors of the ubiquitylation of these substrates.
    Type: Application
    Filed: October 27, 2009
    Publication date: February 25, 2010
    Applicant: Meso Scale Technologies LLC
    Inventors: Ilia DAVYDOV, John H. Kenten, Hans Biebuyck, Pankaj Oberoi
  • Substrates of N-end rule ubiquitylation and methods for measuring the ubiquitylation of these substrates
    Patent number: 7608682
    Abstract: The present invention relates to methods, compositions, compounds and kits for detecting, measuring and modulating protein ubiquitylation via the N-end rule pathway and for identifying novel substrates, enzymes and modulators of N-end rule ubiquitylation. The present invention also relates to specific substrates of N-end rule ubiquitylation as well as activated fragments of these substrates, proteases that expose N-degrons in these substrates, ubiquitin ligases that ubiquitylate these substrates and inhibitors of the ubiquitylation of these substrates.
    Type: Grant
    Filed: October 28, 2003
    Date of Patent: October 27, 2009
    Assignee: Meso Scale Technologies LLC
    Inventors: Ilia Davydov, John H. Kenten, Hans Biebuyck, Pankaj Oberoi
  • Deazaflavin compounds and methods of use thereof
    Patent number: 7498336
    Abstract: The present invention features 5-deazaflavin compounds, pharmaceutical compositions of 5-deazaflavin compounds and methods of treating a patient suffering from cancer, the method comprising administering to a patient one or more 5-deazaflavin compounds of the invention.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: March 3, 2009
    Assignees: The United States of America as represented by the Secretary, Department of Health and Human Services, BioVeris Corporation
    Inventors: Allan M. Weissman, Karen H. Vousden, Jane P. Jensen, Yili Yang, Shengyun Fang, Douglas Woods, John H. Kenten, Ilia Davydov, Yassamin J. Safiran, Pankaj Oberoi
  • Deazaflavin compounds and methods of use thereof
    Publication number: 20060211718
    Abstract: The present invention features 5-deazaflavin compounds, pharmaceutical compositions of 5-deazaflavin compounds and methods of treating a patient suffering from cancer, the method comprising administering to a patient one or more 5-deazaflavin compounds of the invention.
    Type: Application
    Filed: February 12, 2004
    Publication date: September 21, 2006
    Applicants: GOVERNMENT OF THE US, AS REPRESENTED BY THE SEC- RETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, BioVERIS CORPORATION
    Inventors: Allan Weissman, Karen Vousden, Jane Jensen, Yili Yang, Shengyun Fang, Douglas Woods, John Kenten, Ilia Davydov, Yassamin Safiran, Pankaj Oberoi
  • Methods, reagents, kits and apparatus for protein function analysis
    Patent number: 7063946
    Abstract: Apparatus, systems, system components, methods, compositions, and reagents for determining the function and activity of peptides and proteins and for identifying and characterizing molecules that affect these functions and activities. More specifically, methods and reagents used to determine the various activities of peptides and proteins including their binding specificity, binding activity, their enzymatic activity and their ability to act as substrates for enzymes. The disclosed methods are especially suited for the analysis of peptide and protein function where large numbers of peptides and proteins need to be analyzed.
    Type: Grant
    Filed: September 10, 2002
    Date of Patent: June 20, 2006
    Assignee: Meso Scale Technologies, LLC.
    Inventors: John H. Kenten, Hans Biebuyck, Ilia Davydov, Nisar Pampori, Steven Yan Cheng, Stefanie Nelson
  • Substrates of N-end rule ubiquitylation and methods for measuring the ubiquitylation of these substrates
    Publication number: 20040137597
    Abstract: The present invention relates to methods, compositions, compounds and kits for detecting, measuring and modulating protein ubiquitylation via the N-end rule pathway and for identifying novel substrates, enzymes and modulators of N-end rule ubiquitylation. The present invention also relates to specific substrates of N-end rule ubiquitylation as well as activated fragments of these substrates, proteases that expose N-degrons in these substrates, ubiquitin ligases that ubiquitylate these substrates and inhibitors of the ubiquitylation of these substrates.
    Type: Application
    Filed: October 28, 2003
    Publication date: July 15, 2004
    Applicant: Meso Scale Technologies LLC
    Inventors: Ilia Davydov, John H. Kenten, Hans Biebuyck, Pankaj Oberoi
  • Methods, reagents, kits and apparatus for protein function analysis
    Publication number: 20030207290
    Abstract: Apparatus, systems, system components, methods, compositions, and reagents for determining the function and activity of peptides and proteins and for identifying and characterizing molecules that affect these functions and activities. More specifically, methods and reagents used to determine the various activities of peptides and proteins including their binding specificity, binding activity, their enzymatic activity and their ability to act as substrates for enzymes. The disclosed methods are especially suited for the analysis of peptide and protein function where large numbers of peptides and proteins need to be analyzed.
    Type: Application
    Filed: September 10, 2002
    Publication date: November 6, 2003
    Inventors: John H. Kenten, Hans Biebuyck, Ilia Davydov, Nisar Pampori, Steven Yan Cheng, Stefanie Nelson