Patents by Inventor Ilia Korboukh

Ilia Korboukh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION
    Publication number: 20230348524
    Abstract: Among other things, the present disclosure provides technologies for oligonucleotide preparation, particularly chirally controlled oligonucleotide preparation, which technologies provide greatly improved crude purity and yield, and significantly reduce manufacturing costs.
    Type: Application
    Filed: March 17, 2023
    Publication date: November 2, 2023
    Inventors: Keith Andrew Bowman, Chandra Vargeese, David Charles Donnell Butler, Pachamuthu Kandasamy, Mohammed Rowshon Alam, Mamoru Shimizu, Stephany Michelle Standley, Vincent Aduda, Gopal Reddy Bommineni, Snehlata Tripathi, Ilia Korboukh
  • Technologies for oligonucleotide preparation
    Patent number: 11608355
    Abstract: Among other things, the present disclosure provides technologies for oligonucleotide preparation, particularly chirally controlled oligonucleotide preparation, which technologies provide greatly improved crude purity and yield, and significantly reduce manufacturing costs.
    Type: Grant
    Filed: September 17, 2018
    Date of Patent: March 21, 2023
    Assignee: WAVE LIFE SCIENCES LTD.
    Inventors: Keith Andrew Bowman, Chandra Vargeese, David Charles Donnell Butler, Pachamuthu Kandasamy, Mohammed Rowshon Alam, Mamoru Shimizu, Stephany Michelle Standley, Vincent Aduda, Gopal Reddy Bommineni, Snehlata Tripathi, Ilia Korboukh
  • Methods of using nucleotide analogues
    Patent number: 11548909
    Abstract: The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: January 10, 2023
    Assignee: IsoPlexis Corporation
    Inventors: Mong Sano Marma, Jerzy Olejnik, Ilia Korboukh
  • NUCLEOTIDE ANALOGUES
    Publication number: 20220162251
    Abstract: The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
    Type: Application
    Filed: June 28, 2021
    Publication date: May 26, 2022
    Inventors: Mong Sano MARMA, Jerzy Olejnik, Ilia Korboukh
  • Methods for synthesizing nucleotide analogues with disulfide linkers
    Patent number: 11117921
    Abstract: The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
    Type: Grant
    Filed: May 28, 2019
    Date of Patent: September 14, 2021
    Assignee: IsoPlexis Corporation
    Inventors: Mong Sano Marma, Jerzy Olejnik, Ilia Korboukh
  • Nucleotide analogues
    Patent number: 11046726
    Abstract: The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: June 29, 2021
    Assignee: QIAGEN SCIENCES, LLC
    Inventors: Mong Sano Marma, Jerzy Olejnik, Ilia Korboukh
  • TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION
    Publication number: 20200231620
    Abstract: Among other things, the present disclosure provides technologies for oligonucleotide preparation, particularly chirally controlled oligonucleotide preparation, which technologies provide greatly improved crude purity and yield, and significantly reduce manufacturing costs.
    Type: Application
    Filed: September 17, 2018
    Publication date: July 23, 2020
    Inventors: Keith Andrew Bowman, Chandra Vargeese, David Charles Donnell Butler, Pachamuthu Kandasamy, Mohammed Rowshon Alam, Mamoru Shimizu, Stephany Michelle Standley, Vincent Aduda, Gopal Reddy Bommineni, Snehlata Tripathi, Ilia Korboukh
  • Methods for Synthesizing Nucleotide Analogues with Disulfide Linkers
    Publication number: 20190375777
    Abstract: The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
    Type: Application
    Filed: May 28, 2019
    Publication date: December 12, 2019
    Inventors: Mong Sano Marma, Jerzy Olejnik, Ilia Korboukh
  • Methods for synthesizing nucleotide analogues with disulfide linkers
    Patent number: 10336785
    Abstract: The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: July 2, 2019
    Assignee: Qiagen Sciences, LLC
    Inventors: Mong Sano Marma, Jerzy Olejnik, Ilia Korboukh
  • Nucleotide analogues
    Patent number: 10301346
    Abstract: The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: May 28, 2019
    Assignee: Qiagen Sciences, LLC
    Inventors: Mong Sano Marma, Jerzy Olejnik, Ilia Korboukh
  • METHODS OF USING NUCLEOTIDE ANALOGUES
    Publication number: 20180274025
    Abstract: The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
    Type: Application
    Filed: March 22, 2018
    Publication date: September 27, 2018
    Inventors: Mong Sano Marma, Jerzy Olejnik, Ilia Korboukh
  • NUCLEOTIDE ANALOGUES
    Publication number: 20180208774
    Abstract: The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
    Type: Application
    Filed: March 22, 2018
    Publication date: July 26, 2018
    Inventors: Mong Sano Marma, Jerzy Olejnik, Ilia Korboukh
  • NUCLEOTIDE ANALOGUES
    Publication number: 20170130051
    Abstract: The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3?-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.
    Type: Application
    Filed: November 4, 2016
    Publication date: May 11, 2017
    Inventors: Mong Sano Marma, Jerzy Olejnik, Ilia Korboukh