Patents by Inventor Ilias K. Dorziotis

Ilias K. Dorziotis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for synthesizing phosphonic and phosphinic acid compounds
    Patent number: 8222431
    Abstract: The present invention is directed to an improved process for synthesizing phosphonic and phosphinic acid chymase inhibitor compounds.
    Type: Grant
    Filed: October 16, 2008
    Date of Patent: July 17, 2012
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Luigi Anzalone, Daniel J. Pippel, Neelakandha S. Mani, Penina Feibush, Ilias K. Dorziotis, Stefan Horns, Frank J. Villani, Jr.
  • Process for synthesizing phosphonic and phosphinic acid compounds
    Publication number: 20090124801
    Abstract: The present invention is directed to an improved process for synthesizing phosphonic and phosphinic acid chymase inhibitor compounds.
    Type: Application
    Filed: October 16, 2008
    Publication date: May 14, 2009
    Inventors: Luigi Anzalone, Daniel J. Pippel, Neelakandha S. Mani, Penina Feibush, Ilias K. Dorziotis, Stefan Horns, Frank J. Villani, JR.
  • Method of preparing phosphodiesterase IV inhibitors
    Patent number: 5856498
    Abstract: This invention is concerned with a novel process for the preparation of a compound of structural formula I ##STR1## wherein R.sup.1 and R.sup.2 independently are aryl, C.sub.2-15 alkenyl or C.sub.1-15 alkyl, either unsubstituted or substituted with one or three substituents, which can be the same or different, selected from the group consisting of R.sup.a, wherein R.sup.a belongs to a group consisting of C.sub.1-6 alkyl, aryl, halo, --N(R.sup.3).sub.2, --NO.sub.2, --CN, --OR.sup.3, --C.sub.3-6 cycloalkoxy, --CO(R.sup.3), --COOR.sup.3, SO.sub.2 R.sup.3 and --SR.sup.3 ; wherein R3 is selected from the group consisting of hydrogen, C.sub.1-6 alkyl, C.sub.2-6 alkenyl and aryl, said alkyl, alkenyl or aryl optionally substituted with 1 to 3 groups of R.sup.a, which is an important antiasthmatic agent.
    Type: Grant
    Filed: September 16, 1997
    Date of Patent: January 5, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Ilias K. Dorziotis, Ioannis N. Houpis, Jaemoon Lee, Ralph P. Volante