Patents by Inventor Ilio Marsili

Ilio Marsili has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ULTRAFILTRATION FOR PREPARING OUTER MEMBRANE VESICLES
    Publication number: 20170252699
    Abstract: In place of a step of centrifugation during preparation of outer membrane vesicles (OMVs) from bacteria, the invention utilises ultrafiltration. This allows much larger amounts of OMV-containing supernatant to be processed in a much shorter time. Thus the invention provides a process for preparing bacterial OMVs, comprising a step of ultrafiltration. The ultrafiltration step is performed on an aqueous suspension of OMVs after they have been prepared from bacteria and the OMVs remain in suspension after the filtration step. The invention is particularly useful for preparing OMVs from Neisseria meningitidis.
    Type: Application
    Filed: May 19, 2017
    Publication date: September 7, 2017
    Applicant: GLAXOSMITHKLINE BIOLOGICALS S.A.
    Inventors: Roberto OLIVIERI, Fabio SABBATINI, Ilio MARSILI
  • Ultrafiltration for preparing outer membrane vesicles
    Patent number: 9687789
    Abstract: In place of a step of centrifugation during preparation of outer membrane vesicles (OMVs) from bacteria, the invention utilizes ultrafiltration. This allows much larger amounts of OMV-containing supernatant to be processed in a much shorter time. Thus the invention provides a process for preparing bacterial OMVs, comprising a step of ultrafiltration. The ultrafiltration step is performed on an aqueous suspension of OMVs after they have been prepared from bacteria and the OMVs remain in suspension after the filtration step. The invention is particularly useful for preparing OMVs from Neisseria meningitidis.
    Type: Grant
    Filed: July 15, 2004
    Date of Patent: June 27, 2017
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Roberto Olivieri, Fabio Sabbatini, Ilio Marsili
  • Ultrafiltration for preparing outer membrane vesicles
    Publication number: 20070087017
    Abstract: In place of a step of centrifugation during preparation of outer membrane vesicles (OMVs) from bacteria, the invention utilises ultrafiltration. This allows much larger amounts of OMV-containing supernatant to be processed in a much shorter time. Thus the invention provides a process for preparing bacterial OMVs, comprising a step of ultrafiltration. The ultrafiltration step is performed on an aqueous suspension of OMVs after they have been prepared from bacteria and the OMVs remain in suspension after the filtration step. The invention is particularly useful for preparing OMVs from Neisseria meningitidis.
    Type: Application
    Filed: July 15, 2004
    Publication date: April 19, 2007
    Inventors: Robert Olivieri, Fabio Sabbatini, Ilio Marsili