Patents by Inventor Iliyan D. Iliev

Iliyan D. Iliev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE BASED ON HOST-MYCOBIOTA INTERACTIONS
    Publication number: 20230295588
    Abstract: Disclosed herein are methods for selecting a patient suffering from fungal-associated intestinal inflammation for treatment with an IL-1 pathway inhibitor, including inflammasome-blocking drugs based on the presence of candidalysin-secreting C. albicans strains in gut tissue.
    Type: Application
    Filed: December 7, 2022
    Publication date: September 21, 2023
    Applicant: Cornell University
    Inventors: Iliyan D. Iliev, Xin Li
  • Fungal mycobiome as probiotics, diagnostics and therapeutics
    Patent number: 9782389
    Abstract: The present invention relates to methods of using fungal mycobiome as a means of treating and/or diagnosing diseases in a subject. In one embodiment, the present invention provides a method of diagnosing inflammatory bowel disease based on the composition of fungal strains present in the gut of a subject, and treating the subject by administering a probiotic biotherapy. In another embodiment, the present invention provides a method of diagnosing a severe form of ulcerative colitis by detecting the presence of a deficiency in dectin-1 expression in s. fibuligera in the gut of a subject.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: October 10, 2017
    Assignee: CEDARS-SINAI MEDICAL CENTER
    Inventors: David M. Underhill, Iliyan D. Iliev
  • FUNGAL MYCOBIOME AS PROBIOTICS, DIAGNOSTICS AND THERAPEUTICS
    Publication number: 20160317501
    Abstract: The present invention relates to methods of using fungal mycobiome as a means of treating and/or diagnosing diseases in a subject. In one embodiment, the present invention provides a method of diagnosing inflammatory bowel disease based on the composition of fungal strains present in the gut of a subject, and treating the subject by administering a probiotic biotherapy. In another embodiment, the present invention provides a method of diagnosing a severe form of ulcerative colitis by detecting the presence of a deficiency in dectin-1 expression in s. fibuligera in the gut of a subject.
    Type: Application
    Filed: July 18, 2016
    Publication date: November 3, 2016
    Applicant: Cedars-Sinai Medical Center
    Inventors: David M. Underhill, Iliyan D. Iliev
  • Fungal mycobiome as probiotics, diagnostics and therapeutics
    Patent number: 9421233
    Abstract: The present invention relates to methods of using fungal mycobiome as a means of treating and/or diagnosing diseases in a subject. In one embodiment, the present invention provides a method of diagnosing inflammatory bowel disease based on the composition of fungal strains present in the gut of a subject, and treating the subject by administering a probiotic biotherapy. In another embodiment, the present invention provides a method of diagnosing a severe form of ulcerative colitis by detecting the presence of a deficiency in dectin-1 expression in s. fibuligera in the gut of a subject.
    Type: Grant
    Filed: April 26, 2013
    Date of Patent: August 23, 2016
    Assignee: Cedars-Sinai Medical Center
    Inventors: David M. Underhill, Iliyan D. Iliev
  • FUNGAL MYCOBIOME AS PROBIOTICS, DIAGNOSTICS AND THERAPEUTICS
    Publication number: 20150110834
    Abstract: The present invention relates to methods of using fungal mycobiome as a means of treating and/or diagnosing diseases in a subject. In one embodiment, the present invention provides a method of diagnosing inflammatory bowel disease based on the composition of fungal strains present in the gut of a subject, and treating the subject by administering a probiotic biotherapy. In another embodiment, the present invention provides a method of diagnosing a severe form of ulcerative colitis by detecting the presence of a deficiency in dectin-1 expression in s. fibuligera in the gut of a subject.
    Type: Application
    Filed: April 26, 2013
    Publication date: April 23, 2015
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: David M. Underhill, Iliyan D. Iliev