Patents by Inventor Ilker K. Sariyer

Ilker K. Sariyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACOLOGIC APPROACH FOR SUPPRESSION OF CORONAVIRUSES
    Publication number: 20240009221
    Abstract: Compositions for prevention or treatment for the SARS family of coronaviruses, e.g., SARS-CoV-2 and SARS-OC43 (common cold virus), include non-nucleoside reverse transcriptase inhibitors (NNRTI), such as rilpivirine, and nucleoside-analogue antiviral agents, such as remdesivir.
    Type: Application
    Filed: April 14, 2023
    Publication date: January 11, 2024
    Inventors: Kamel Khalili, Shuren Liao, Ilker K. Sariyer
  • CRISPR/CAS9 SYSTEM AS AN AGENT FOR INHIBITION OF POLYOMA JC INFECTION
    Publication number: 20220380812
    Abstract: Provided herein are gene editing compositions and methods that effectively modulate and/or edit a JCV genome. The effective modulation and/or editing is, in an aspect, achieved by gene editing compositions targeting a NCCR region, an early coding gene, and/or a late coding gene.
    Type: Application
    Filed: November 11, 2020
    Publication date: December 1, 2022
    Inventors: Kamel KHALILI, Hassen S. WOLLEBO, Jennifer GORDON, Ilker K. SARIYER
  • Method for detecting polyomavirus reactivation
    Patent number: 10690668
    Abstract: The invention provides methods of detection and monitoring of polyomavirus reactivation and active polyomavirus infections using a biological fluid sample. Also provided are methods of risk assessment and risk monitoring of developing a polyomavirus-associated disease.
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: June 23, 2020
    Assignee: Temple University—Of The Commonwealth System Of Higher Education
    Inventors: Kamel Khalili, Ilker K. Sariyer
  • COMBINATION THERAPIES FOR ERADICATING FLAVIVIRUS INFECTIONS IN SUBJECTS
    Publication number: 20190365862
    Abstract: Compositions that specifically cleave target sequences in Flavivirus, for example Zika virus include a Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) associated endonuclease, a guide RNA sequence complementary to a target sequence in a Zika virus and an anti-viral agent. These compositions are administered to a subject for treating an infection or at risk for contracting a Zika virus infection.
    Type: Application
    Filed: October 12, 2017
    Publication date: December 5, 2019
    Inventors: Kamel Khalili, Ilker K. Sariyer, Hassen Wollebo
  • METHOD FOR DETECTING POLYOMAVIRUS REACTIVATION
    Publication number: 20150010901
    Abstract: The invention provides methods of detection and monitoring of polyomavirus reactivation and active polyomavirus infections using a biological fluid sample. Also provided are methods of risk assessment and risk monitoring of developing a polyomavirus-associated disease.
    Type: Application
    Filed: January 29, 2013
    Publication date: January 8, 2015
    Applicant: TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Kamel Khalili, Ilker K. Sariyer