Patents by Inventor Ill-Ju Bae

Ill-Ju Bae has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230181632
    Abstract: Disclosed herein is a pharmaceutical composition comprising tetraarsenic hexoxide as an active ingredient. Having excellent antiviral activity against coronaviruses, the pharmaceutical composition can be advantageously applied to the prevention or treatment of coronavirus diseases.
    Type: Application
    Filed: April 8, 2021
    Publication date: June 15, 2023
    Applicant: CHEMAS CO., LTD.
    Inventors: Ill Ju BAE, Seong Jin KIM, Kwang Soo LYOO, Kyung Min YANG, Zhaoyan WU, Min Jung SON, Kyoungwha PANG
  • Patent number: 11191779
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating cancer and a method for producing same, the composition comprising tetraarsenic hexoxide in which the content of tetraarsenic hexoxide crystalline polymorph a (As4O6-a) is 99% or more. The composition of the present invention exhibits an excellent cancer cell proliferation inhibition effect and thus can be useful as an anticancer drug.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: December 7, 2021
    Assignee: CHEMAS CO., LTD.
    Inventors: Ill Ju Bae, Zenglin Lian
  • Patent number: 11154530
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating liver cancer and a method for producing same, the composition comprising tetraarsenic hexoxide in which the content of tetraarsenic hexoxide crystalline polymorph a (As4O6-a) is 99% or more. The composition of the present invention exhibits an excellent cancer cell proliferation inhibition effect and thus can be useful as an anticancer drug.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: October 26, 2021
    Assignee: CHEMAS CO., LTD.
    Inventors: Ill Ju Bae, Zenglin Lian
  • Publication number: 20200069635
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating liver cancer and a method for producing same, the composition comprising tetraarsenic hexoxide in which the content of tetraarsenic hexoxide crystalline polymorph a (As4O6-a) is 99% or more. The composition of the present invention exhibits an excellent cancer cell proliferation inhibition effect and thus can be useful as an anticancer drug.
    Type: Application
    Filed: December 4, 2017
    Publication date: March 5, 2020
    Applicant: CHEMAS CO., LTD.
    Inventors: Ill Ju BAE, Zenglin LIAN
  • Patent number: 10525079
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating breast cancer which includes tetraarsenic hexoxide in which a crystalline polymorph a(As4O6-a), of tetraarsenic hexoxide is 99% or higher, and to a method for producing the same. The composition of the present invention exhibits excellent effects of inhibiting the proliferation and metastasis of cancer cells, and thus can be usefully used as an anticancer agent.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: January 7, 2020
    Assignee: CHEMAS CO., LTD.
    Inventors: Ill Ju Bae, Zenglin Lian
  • Publication number: 20200000846
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating cancer and a method for producing same, the composition comprising tetraarsenic hexoxide in which the content of tetraarsenic hexoxide crystalline polymorph a (As4O6-a) is 99% or more. The composition of the present invention exhibits an excellent cancer cell proliferation inhibition effect and thus can be useful as an anticancer drug.
    Type: Application
    Filed: December 4, 2017
    Publication date: January 2, 2020
    Applicant: CHEMAS CO., LTD.
    Inventors: Ill Ju BAE, Zenglin LIAN
  • Patent number: 10493100
    Abstract: The present invention relates to a pharmaceutical composition which is for preventing or treating brain cancer and includes at least 99% of a crystal polymorph of tetraarsenic hexoxide a (As4O6-a), and to a method for preparing same. A composition according to the present invention exhibits excellent cancer cell proliferation inhibition and metastasis inhibition effects, and thus may be usefully used as an anti-cancer agent.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: December 3, 2019
    Assignee: CHEMAS CO., LTD.
    Inventors: Ill Ju Bae, Zenglin Lian
  • Publication number: 20190328780
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating breast cancer which includes tetraarsenic hexoxide in which a crystalline polymorph a(As4O6-a), of tetraarsenic hexoxide is 99% or higher, and to a method for producing the same. The composition of the present invention exhibits excellent effects of inhibiting the proliferation and metastasis of cancer cells, and thus can be usefully used as an anticancer agent.
    Type: Application
    Filed: November 17, 2017
    Publication date: October 31, 2019
    Applicant: CHEMAS CO., LTD.
    Inventors: Ill Ju BAE, Zenglin LIAN
  • Publication number: 20190328779
    Abstract: The present invention relates to a pharmaceutical composition which is for preventing or treating brain cancer and includes at least 99% of a crystal polymorph of tetraarsenic hexoxide a (As4O6-a), and to a method for preparing same. A composition according to the present invention exhibits excellent cancer cell proliferation inhibition and metastasis inhibition effects, and thus may be usefully used as an anti-cancer agent.
    Type: Application
    Filed: September 7, 2017
    Publication date: October 31, 2019
    Applicant: CHEMAS CO., LTD.
    Inventors: Ill Ju BAE, Zenglin LIAN
  • Publication number: 20110250292
    Abstract: Disclosed is a composition for improving radiotherapy for cancer, containing tetra-arsenic oxide (As4O6) as an active ingredient. The disclosed composition for improving radiotherapy for cancer improves the efficiency of radiotherapy, and thus reduces side effects caused by the high-dose radiation. The disclosed composition uses tetra-arsenic oxide, the safety of which is proven, from among conventional arsenic compound derivatives, to prevent side effects caused by arsenic trioxide, taxol, cisplatin, fluorouracil, leuprolide, or the like, which are known as conventional radiosensitizers.
    Type: Application
    Filed: November 30, 2009
    Publication date: October 13, 2011
    Applicant: CHONJISAN CO., LTD.
    Inventors: Ill Ju Bae, Sae Gwang Park
  • Patent number: 7261906
    Abstract: A process for preparing As4O6 comprises successively heating and cooling a mixture of natural Sinsuk and 40% alcohol in a ratio of about 1: about 1 for about 1 to about 2 hour(s) resulting in a product, successively washing the product with distilled water thereby forming washed precipitates, maintaining the washed precipitates at about ?40° C. for 24 hours, defrosting, filtering, and drying the precipitates, and successively heating and cooling the precipitates to obtain the final As4O6 product.
    Type: Grant
    Filed: May 16, 2003
    Date of Patent: August 28, 2007
    Inventors: Ill-Ju Bae, Jong-Bae Kim, Choong-Ki Eun, Seung-Kyu Song, Byung-Sun Suh, Kwan-Hee Lee, Myoung-Sool Doo, Jin-Hwan Kwak, Byung-Doo Song, Taek-Joon Yoon, Tae-Bong Kang, Choon-Ho Park
  • Publication number: 20040018246
    Abstract: This invention is about the identification of the HD-2, a natural chemical substance that was separated and purified from a natural product, Sinsuk, as arsenic hexoxide (As4O6) and about its therapeutic efficacy as an anti-cancer drug and pharmaceutical composition.
    Type: Application
    Filed: May 16, 2003
    Publication date: January 29, 2004
    Applicant: Ill-Ju BAE
    Inventors: Ill-Ju Bae, Jong-Bae Kim, Choong-Ki Eun, Seung-Kyu Song, Byung-Sun Suh, Kwan-Hee Lee, Myoung-Sool Doo, Jin-Hwan Kwak, Byung-Doo Song, Taek-Joon Yoon, Tae-Bong Kang, Choon-Ho Park
  • Patent number: 6589567
    Abstract: This invention is about the identification of the HD-2, a natural chemical substance that was separated and purified from a natural product, Sinsuk, as arsenic hexoxide (As4O6) and about its therapeutic efficacy as an anti-cancer drug and pharmaceutical composition. Arsenic hexoxide (As4O6), a natural chemical substance obtained from Sinsuk after eliminating the toxic property, has a potent anti-cancer efficacy by its direct cytotoxicity on tumor cells and suppresses the formation of new blood vessels of tumor masses, which results in complete cure of malignant cancers.
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: July 8, 2003
    Inventors: Ill-Ju Bae, Jong-Bae Kim, Choong-Ki Eun, Seung-Kyu Song, Byung-Sun Suh, Kwan-Hee Lee, Myoung-Sool Doo, Jin-Hwan Kwak, Byung-Doo Song, Taek-Joon Yoon, Tae-Bong Kang, Choon-Ho Park
  • Publication number: 20020028253
    Abstract: This invention is about the identification of the HD-2, a natural chemical substance that was separated and purified from a natural product, Sinsuk, as arsenic hexoxide (As4O6) and about its therapeutic efficacy as an anti-cancer drug and pharmaceutical composition. Arsenic hexoxide (As4O6), a natural chemical substance obtained from Sinsuk after eliminating the toxic property, has a potent anti-cancer efficacy by its direct cytotoxicity on tumor cells and suppresses the formation of new blood vessels of tumor masses, which results in complete cure of malignant cancers.
    Type: Application
    Filed: September 14, 2001
    Publication date: March 7, 2002
    Inventors: Ill-Ju Bae, Jong-Bae Kim, Choong-Ki Eun, Seung-Kyu Song, Byung-Sun Suh, Kwan-Hee Lee, Myoung-Sool Doo, Jin-Hwan Kwak, Byung-Doo Song, Taek-Joon Yoon, Tae-Bong Kang, Choon-Ho Park
  • Patent number: 6309672
    Abstract: This invention is about the identification of the HD-2, a natural chemical substance that was separated and purified from a natural product, Sinsuk, as arsenic hexoxide (As4O6) and about its therapeutic efficacy as an anti-cancer drug and pharmaceutical composition. Arsenic hexoxide (As4O6), a natural chemical substance obtained from Sinsuk after eliminating the toxic property, has a potent anti-cancer efficacy by its direct cytotoxicity on tumor cells and suppresses the formation of new blood vessels of tumor masses, which results in complete cure of malignant cancers.
    Type: Grant
    Filed: June 26, 1998
    Date of Patent: October 30, 2001
    Inventors: Ill-Ju Bae, Jong-Bae Kim, Choong-Ki Eun, Seung-Kyu Song, Byung-Sun Suh, Kwan-Hee Lee, Myoung-Sool Doo, Jin-Hwan Kwak, Byung-Doo Song, Taek-Joon Yoon, Tae-Bong Kang, Choon-Ho Park