Patents by Inventor Ilpo VATTULAINEN

Ilpo VATTULAINEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CD95 POLYPEPTIDES
    Publication number: 20250136662
    Abstract: The present invention relates to an effector polypeptide comprising (i) an amino acid sequence at least 70% identical to the amino acid sequence RSNLGWLCLLLLPIPLIVWVKRK (SEQ ID NO: 1); and (ii) an exchange of an amino acid to a non-identical amino acid at least one position selected from the list consisting of positions 1, 2, 3, 19, 22, and 23 of the amino acid sequence of (i). The present invention also relates to a polynucleotide comprising a nucleic acid sequence encoding the aforesaid effector polypeptide. and to related host cells. pharmaceutical compositions. and uses. and to related uses in medicine, in particular in treating and/or preventing cancer, inflammatory disease, or acute or chronic neurodegenerative disease.
    Type: Application
    Filed: November 24, 2022
    Publication date: May 1, 2025
    Applicants: Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts, Universität Heidelberg
    Inventors: Ana MARTIN-VILLALBA, Britta BRÜGGER, Ilpo VATTULAINEN, Fabio LOLICATO, Gülce Sila GÜLCÜLER, Susanne KLEBER