Patents by Inventor Ilya APARIN

Ilya APARIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REAGENTS AND METHODS USED IN DEPROTECTION OF 3'-O-AMINO POLYNUCLEOTIDES
    Publication number: 20250154547
    Abstract: This disclosure relates to an enzymatic method of synthesizing a polynucleotide, comprising a deprotecting step which uses as a deprotecting agent a specific phosphonate compound. It also pertains to a method for deprotecting 3?-O-amino elongated fragments of a polynucleotide in an enzymatic method of synthesizing a polynucleotide, comprising contacting the elongated fragments with this phosphonate compound. This disclosure further relates to a kit for synthesizing a polynucleotide comprising one or more vials of synthesis reagents, at least one of which contains an effective amount of a phosphonate compound and to a specific method for preparing said phosphonate compound.
    Type: Application
    Filed: October 30, 2024
    Publication date: May 15, 2025
    Inventors: Ilya APARIN, Mikhael SOSKINE, Weidong WU, Adeline VEILLET
  • Reagents and methods used in deprotection of 3'-O-amino polynucleotides
    Patent number: 12163172
    Abstract: This disclosure relates to an enzymatic method of synthesizing a polynucleotide, comprising a deprotecting step which uses as a deprotecting agent a specific phosphonate compound. It also pertains to a method for deprotecting 3?-O-amino elongated fragments of a polynucleotide in an enzymatic method of synthesizing a polynucleotide, comprising contacting the elongated fragments with this phosphonate compound. This disclosure further relates to a kit for synthesizing a polynucleotide comprising one or more vials of synthesis reagents, at least one of which contains an effective amount of a phosphonate compound and to a specific method for preparing said phosphonate compound.
    Type: Grant
    Filed: May 3, 2024
    Date of Patent: December 10, 2024
    Assignee: DNA SCRIPT
    Inventors: Ilya Aparin, Mikhael Soskine, Weidong Wu, Adeline Veillet
  • REAGENTS AND METHODS USED IN DEPROTECTION OF 3'-O-AMINO POLYNUCLEOTIDES
    Publication number: 20240368656
    Abstract: This disclosure relates to an enzymatic method of synthesizing a polynucleotide, comprising a deprotecting step which uses as a deprotecting agent a specific phosphonate compound. It also pertains to a method for deprotecting 3?-O-amino elongated fragments of a polynucleotide in an enzymatic method of synthesizing a polynucleotide, comprising contacting the elongated fragments with this phosphonate compound. This disclosure further relates to a kit for synthesizing a polynucleotide comprising one or more vials of synthesis reagents, at least one of which contains an effective amount of a phosphonate compound and to a specific method for preparing said phosphonate compound.
    Type: Application
    Filed: May 3, 2024
    Publication date: November 7, 2024
    Applicant: DNA Script
    Inventors: Ilya APARIN, Mikhael SOSKINE, Weidong WU, Adeline Veillet