Patents by Inventor Ilya Bezprozvanny

Ilya Bezprozvanny has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SK CHANNEL POSITIVE ALLOSTERIC MODULATORS
    Publication number: 20230159500
    Abstract: A compound according to Formula (I) or a pharmaceutically acceptable salt thereof: is provided. X1 is N or C-Y; Y is H, halogen, NH2, OH, SH, alkyl, aryl, alkoxy, or aryloxy; A is O, NH, S, Se, or CH2, B is X2 is N or CH; and Z is NH, CH2, S, O, or Se.
    Type: Application
    Filed: September 29, 2022
    Publication date: May 25, 2023
    Inventors: Miao Zhang, Keykavous Parang, Naglaa Ibrahim, Young Woo Nam, Ilya Bezprozvanny, Meng Cui
  • Use of pridopidine to improve cognitive function and for treating Alzheimer's disease
    Patent number: 11471449
    Abstract: This invention provides a method of improving cognitive function in a subject comprising periodically administering to the subject an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to improve a cognitive function in the subject. The invention also provides a method of treating a subject afflicted with Alzheimer's disease, comprising periodically administering to the subject a pharmaceutical composition comprising an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to treat the subject.
    Type: Grant
    Filed: October 3, 2019
    Date of Patent: October 18, 2022
    Assignees: Prilenia Neurotherapeutics Ltd., The Board of Regents of the University of Texas System
    Inventors: Michal Geva, Ilya Bezprozvanny, Merav Bassan, Michael Hayden
  • Use of pridopidine to improve cognitive function and for treating Alzheimer's disease
    Patent number: 10603311
    Abstract: This invention provides a method of improving cognitive function in a subject comprising periodically administering to the subject an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to improve a cognitive function in the subject. The invention also provides a method of treating a subject afflicted with Alzheimer's disease, comprising periodically administering to the subject a pharmaceutical composition comprising an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to treat the subject.
    Type: Grant
    Filed: February 24, 2016
    Date of Patent: March 31, 2020
    Assignees: PRILENIA NEUROTHERAPEUTICS LTD., THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Michal Geva, Ilya Bezprozvanny, Merav Bassan, Michael Hayden
  • USE OF PRIDOPIDINE TO IMPROVE COGNITIVE FUNCTION AND FOR TREATING ALZHEIMER'S DISEASE
    Publication number: 20200093813
    Abstract: This invention provides a method of improving cognitive function in a subject comprising periodically administering to the subject an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to improve a cognitive function in the subject. The invention also provides a method of treating a subject afflicted with Alzheimer's disease, comprising periodically administering to the subject a pharmaceutical composition comprising an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to treat the subject.
    Type: Application
    Filed: October 3, 2019
    Publication date: March 26, 2020
    Applicants: PRILENIA NEUROTHERAPEUTICS LTD., THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Michal Geva, Ilya Bezprozvanny, Merav Bassan, Michael Hayden
  • ACTIVATION OF NEURONAL STORE-OPERATED CALCIUM ENTRY PATHWAY FOR THE TREATMENT OF ALZHEIMER'S DISEASE
    Publication number: 20180147206
    Abstract: The present disclosure provides for new methods of treating Alzheimer's Disease. In particular, it concerns the activation of neuronal store-operated calcium entry pathway in Alzheimer's Disease patients.
    Type: Application
    Filed: May 4, 2016
    Publication date: May 31, 2018
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Ilya BEZPROZVANNY, Hua ZHANG
  • USE OF PRIDOPIDINE TO IMPROVE COGNITIVE FUNCTION AND FOR TREATING ALZHEIMER'S DISEASE
    Publication number: 20160243098
    Abstract: This invention provides a method of improving cognitive function in a subject comprising periodically administering to the subject an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to improve a cognitive function in the subject. The invention also provides a method of treating a subject afflicted with Alzheimer's disease, comprising periodically administering to the subject a pharmaceutical composition comprising an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to treat the subject.
    Type: Application
    Filed: February 24, 2016
    Publication date: August 25, 2016
    Applicants: Teva Pharmaceuticals International GmbH, The Board of Regents of The University of Texas System
    Inventors: Michal Geva, Ilya Bezprozvanny, Merav Bassan, Michael Hayden
  • Peptides of CaV2.2 that inhibit pain
    Patent number: 7829688
    Abstract: The present invention relates to peptides of CaV2.2 and their use in the treatment of pain. The sequence of the peptides is derived from the C-terminus of CaV2.2. and is believed to inhibit the interaction of CaV2.2 with Mint1-PDZ1. The invention is related to use of this peptide to treat pain and to use of this peptide in binding reaction with int-PDZ to screen for small molecules that can inhibit pain.
    Type: Grant
    Filed: August 12, 2008
    Date of Patent: November 9, 2010
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Mary Garry, Ilya Bezprozvanny
  • PEPTIDES OF CAV2.2 THAT INHIBIT PAIN
    Publication number: 20090068148
    Abstract: The present invention relates to peptides of CaV2.2 and their use in the treatment of pain. The sequence of the peptides is derived from the C-terminus of CaV2.2. and is believed to inhibit the interaction of CaV2.2 with Mint1-PDZ1. The invention is related to use of this peptide to treat pain and to use of this peptide in binding reaction with int-PDZ to screen for small molecules that can inhibit pain.
    Type: Application
    Filed: August 12, 2008
    Publication date: March 12, 2009
    Inventors: Mary Garry, Ilya Bezprozvanny
  • Peptides of CaV2.2 that inhibit pain
    Patent number: 7410950
    Abstract: The present invention relates to peptides of CaV2.2 and their use in the treatment of pain. The sequence of the peptides is derived from the C-terminus of CaV2.2. and is believed to inhibit the interaction of CaV2.2 with Mint1-PDZ1. The invention is related to use of this peptide to treat pain and to use of this peptide in binding reaction with int-PDZ to screen for small molecules that can inhibit pain.
    Type: Grant
    Filed: March 31, 2005
    Date of Patent: August 12, 2008
    Assignee: Board of Regents, The University of Texas System
    Inventors: Mary Garry, Ilya Bezprozvanny
  • Peptides of CaV2.2 that inhibit pain
    Publication number: 20050267036
    Abstract: The present invention relates to peptides of CaV2.2 and their use in the treatment of pain. The sequence of the peptides is derived from the C-terminus of CaV2.2. and is believed to inhibit the interaction of CaV2.2 with Mint1-PDZ1. The invention is related to use of this peptide to treat pain and to use of this peptide in binding reaction with int-PDZ to screen for small molecules that can inhibit pain.
    Type: Application
    Filed: March 31, 2005
    Publication date: December 1, 2005
    Inventors: Mary Garry, Ilya Bezprozvanny