Patents by Inventor Ilya Serebriiski

Ilya Serebriiski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating MYC-amplified tumors with RNA-polymerase II inhibitors
    Patent number: 9993458
    Abstract: Systems and methods for determining whether a cancer patient may respond to inhibition of RNA polymerase II as a treatment for the patient are provided. Inhibition of RNA polymerase II may be by way of chemotherapy with an agent such as triptolide, an analog of triptolide, or a prodrug form of triptolide. The cancer patient may be a pancreatic cancer patient, an ovarian cancer patient, a gastric cancer patient, or an esophageal cancer patient. The patient may have any cancer in which c-Myc is over-expressed or over-amplified.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: June 12, 2018
    Assignees: Institute For Cancer Research, NexusPharma, Inc.
    Inventors: Igor Astsaturov, Vladimir Khazak, Ilya Serebriiski
  • C-MYC as a Biomarker for Tumor Sensitivity to Treatment with RNA Polymerase II Inhibition
    Publication number: 20160354339
    Abstract: Systems and methods for determining whether a cancer patient may respond to inhibition of RNA polymerase II as a treatment for the patient are provided. Inhibition of RNA polymerase II may be by way of chemotherapy with an agent such as triptolide, an analog of triptolide, or a prodrug form of triptolide. The cancer patient may be a pancreatic cancer patient, an ovarian cancer patient, a gastric cancer patient, or an esophageal cancer patient. The patient may have any cancer in which c-Myc is over-expressed or over-amplified.
    Type: Application
    Filed: August 22, 2016
    Publication date: December 8, 2016
    Inventors: Igor Astsaturov, Vladimir Khazak, Ilya Serebriiski