Patents by Inventor Iman El-Hariry

Iman El-Hariry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATING CANCER WITH HSP90 INHIBITORY COMPOUNDS
    Publication number: 20150150850
    Abstract: Methods of treating cancer with a compound of formulae (I) or (Ia) are disclosed. Also provided are methods of treating a cancer with a mutation in ALK or a c-MET mutation with a compound of formulae (I) or (Ia). Further provided are methods of treating non-small cell lung cancer with a mutation in ALK with a compound of formulae (I) or (Ia): a tautomer, or a pharmaceutically acceptable salt thereof, wherein the variables in the structural formulae are defined herein.
    Type: Application
    Filed: December 5, 2014
    Publication date: June 4, 2015
    Inventors: Iman El-Hariry, David Proia, Vojo Vukovic
  • Treating cancer with HSP90 inhibitory compounds
    Patent number: 8906885
    Abstract: Methods of treating cancer with a compound of formulae (I) or (1a) are disclosed. Also provided are methods of treating a cancer with a mutation in ALK or a c-MET mutation with a compound of formulae (I) or (1a). Further provided are methods of treating non-small cell lung cancer with a mutation in ALK with a compound of formulae (I) or (1a); a tautomer, or a pharmaceutically acceptable salt thereof, wherein the variables structural formulae are defined herein.
    Type: Grant
    Filed: July 9, 2012
    Date of Patent: December 9, 2014
    Assignee: Synta Pharmaceuticals Corp.
    Inventors: Iman El-Hariry, David Proia, Vojo Vukovic
  • TREATING CANCER WITH HSP90 INHIBITORY COMPOUNDS
    Publication number: 20140294808
    Abstract: Methods of treating cancer with a compound of formulae (I) or (Ia) are disclosed. Also provided are methods of treating a cancer with a mutation in ALK or a c-MET mutation with a compound of formulae (I) or (Ia). Further provided are methods of treating non-small cell lung cancer with a mutation in ALK with a compound of formulae (I) or (Ia); a tautomer, or a pharmaceutically acceptable salt thereof, wherein the variables structural formulae are defined herein.
    Type: Application
    Filed: July 9, 2012
    Publication date: October 2, 2014
    Applicant: SYNTA PHARMACEUTICALS CORP.
    Inventors: Iman El-Hariry, David Proia, Vojo Vukovic
  • Cancer Treatment Method
    Publication number: 20100063074
    Abstract: The present invention relates to a method of treating cancer in a mammal by administration of 4-quinazolinamines and pharmaceutical compositions containing the same. In particular, the method relates to a methods of treating cancers which are mediated by the tyrosine kinases EGFR and/or erbB2 by administration of N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine and salts and solvates thereof.
    Type: Application
    Filed: June 1, 2005
    Publication date: March 11, 2010
    Inventors: Mark S. Berger, Tona Morgan Gilmer, Arundathy Nirmalini Pandite, David Rusnak, Neil L. Spector, Iman El-Hariry