Patents by Inventor Imene Chebbi

Imene Chebbi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210261857
    Abstract: The use, especially in vitro, of a particle including at least one ferrimagnetic or ferromagnetic iron oxide nanoparticle associated with at least one compound, in which the compound dissociates from the at least one ferrimagnetic or ferromagnetic iron oxide nanoparticle and/or chemically modifies itself, following a physicochemical disturbance applied on the particle, as a probe.
    Type: Application
    Filed: April 30, 2021
    Publication date: August 26, 2021
    Applicant: NANOBACTERIE
    Inventors: Edouard ALPHANDÉRY, Imène CHEBBI
  • Patent number: 10974059
    Abstract: A method for the treatment of tumor(s) or tumor cell(s) or cancer(s) in a subject in need by the generation of heat. The latter is produced by chains of magnetosomes extracted from whole magnetotactic bacteria and subjected to an alternating magnetic field. These chains of magnetosomes yield efficient antitumoral activity whereas magnetosomes unbound from the chains or kept within the whole bacteria produce poor or no antitumoral activity. The introduction of various chemicals such as chelating agents and/or transition metals within the growth medium of the bacteria improves the heating properties of the chains of magnetosomes. Moreover, the insertion of the chains of magnetosomes within a lipid vesicle is also suggested in order to favor their rotation in vivo and hence to improve their heating capacity. The vesicle can contain an antitumoral agent together with the chains of magnetosomes. In this case, the agent is released within the tumors by heating the vesicle.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: April 13, 2021
    Assignee: NANOBACTERIE
    Inventors: Edouard Alphandery, Stephanie Faure, Imene Chebbi
  • Patent number: 10252073
    Abstract: A method for the treatment of tumor(s), tumor cell(s), cancer(s) in a subject by the generation of heat. The latter is produced by chains of magnetosomes extracted from whole magnetotactic bacteria and subjected to an alternating magnetic field. These chains of magnetosomes yield efficient antitumoral activity whereas magnetosomes unbound from the chains or kept within the whole bacteria produce poor or no antitumoral activity. The introduction of various chemicals such as chelating agents and/or transition metals within the growth medium of the bacteria improves the heating properties of the chains of magnetosomes. Moreover, the insertion of the chains of magnetosomes within a lipid vesicle is also suggested in order to favor their rotation in vivo and hence to improve their heating capacity. The vesicle can contain an antitumoral agent together with the chains of magnetosomes, and the agent is released within the tumors by heating the vesicle.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: April 9, 2019
    Assignee: NANOBACTERIE
    Inventors: Edouard Alphandery, Stéphanie Faure, Imène Chebbi
  • Patent number: 10238886
    Abstract: A method for the treatment of tumor(s) or tumor cell(s) or cancer(s) in a subject in need by the generation of heat. The latter is produced by chains of magnetosomes extracted from whole magnetotactic bacteria and subjected to an alternating magnetic field. These chains of magnetosomes yield efficient antitumoral activity whereas magnetosomes unbound from the chains or kept within the whole bacteria produce poor or no antitumoral activity. The introduction of various chemicals such as chelating agents and/or transition metals within the growth medium of the bacteria improves the heating properties of the chains of magnetosomes. Moreover, the insertion of the chains of magnetosomes within a lipid vesicle is also suggested in order to favor their rotation in vivo and hence to improve their heating capacity. The vesicle can contain an antitumoral agent together with the chains of magnetosomes. In this case, the agent is released within the tumors by heating the vesicle.
    Type: Grant
    Filed: November 18, 2010
    Date of Patent: March 26, 2019
    Assignee: NANOBACTERIE
    Inventors: Edouard Alphandery, Stéphanie Faure, Imène Chebbi
  • Publication number: 20180244987
    Abstract: A particle probe including at least one ferrimagnetic or ferromagnetic iron oxide nanoparticle associated with at least one compound, in which the at least one compound dissociates from the at least one ferrimagnetic or ferromagnetic iron oxide nanoparticle and/or chemically modifies itself, following a physicochemical disturbance applied on the particle probe.
    Type: Application
    Filed: October 21, 2016
    Publication date: August 30, 2018
    Inventors: Edouard ALPHANDÉRY, Imène CHEBBI
  • Publication number: 20170157253
    Abstract: A method for the treatment of tumor(s), tumor cell(s), cancer(s) in a subject by the generation of heat. The latter is produced by chains of magnetosomes extracted from whole magnetotactic bacteria and subjected to an alternating magnetic field. These chains of magnetosomes yield efficient antitumoral activity whereas magnetosomes unbound from the chains or kept within the whole bacteria produce poor or no antitumoral activity. The introduction of various chemicals such as chelating agents and/or transition metals within the growth medium of the bacteria improves the heating properties of the chains of magnetosomes. Moreover, the insertion of the chains of magnetosomes within a lipid vesicle is also suggested in order to favor their rotation in vivo and hence to improve their heating capacity. The vesicle can contain an antitumoral agent together with the chains of magnetosomes, and the agent is released within the tumors by heating the vesicle.
    Type: Application
    Filed: February 15, 2017
    Publication date: June 8, 2017
    Inventors: Edouard ALPHANDERY, Stéphanie FAURE, Imène CHEBBI
  • Patent number: 9359589
    Abstract: The invention relates to the use of at least one chelating agent, including an iron chelating agent, in order to stimulate the growth of magnetotactic bacteria.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: June 7, 2016
    Assignees: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Edouard Alphandery, Iméne Chebbi
  • Publication number: 20140106436
    Abstract: The invention relates to the use of at least one chelating agent, including an iron chelating agent, in order to stimulate the growth of magnetotactic bacteria.
    Type: Application
    Filed: May 4, 2012
    Publication date: April 17, 2014
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
    Inventors: Edouard Alphandery, Imène Chebbi
  • Publication number: 20120302819
    Abstract: In this disclosure, we describe a method for the treatment of tumor(s) or tumor cell(s) or cancer(s) in a subject in need by the generation of heat. The latter is produced by chains of magnetosomes extracted from whole magnetotactic bacteria and subjected to an alternative magnetic field. These chains of magnetosomes yield efficient antitumoral activity whereas magnetosomes unbound from the chains or kept within the whole bacteria produce poor or no antitumoral activity. The introduction of various chemicals such as chelating agents and/or transition metals within the growth medium of the bacteria improves the heating properties of the chains of magnetosomes. Moreover, the insertion of the chains of magnetosomes within a lipid vesicle is also suggested in order to favor their rotation in vivo and hence to improve their heating capacity. The vesicle can contain an antitumoral agent together with the chains of magnetosomes. In this case, the agent is released within the tumors by heating the vesicle.
    Type: Application
    Filed: November 18, 2010
    Publication date: November 29, 2012
    Inventors: Edouard Alphandery, Stéphanie Faure, Imène Chebbi