Patents by Inventor Immacolata Busiello

Immacolata Busiello has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RECOMBINANT YEAST FOR THE PRODUCTION OF OLIGOPEPTIDE
    Publication number: 20230366002
    Abstract: The invention relates to a recombinant yeast wherein the PEP4 gene is inactivated. Said yeast is useful for the production of oligopeptides.
    Type: Application
    Filed: September 27, 2021
    Publication date: November 16, 2023
    Applicant: LESAFFRE ET COMPAGNIE
    Inventors: Simona Daly, Stefano Galliani, Immacolata Busiello, Matteo Grigis, Auro Roberto Tagliani
  • Formulations containing and superoxide dismutase (SOD) to control obesity
    Patent number: 9555082
    Abstract: Disclosed is a composition containing Saccharomyces cerevisiae var boulardii and the enzyme superoxide dismutase.
    Type: Grant
    Filed: August 2, 2012
    Date of Patent: January 31, 2017
    Assignee: Gnosis S.p.A.
    Inventors: Ignazio Castagliuolo, Paola Brun, Immacolata Busiello, Niccolo Miraglia
  • Low-Molecular-Weight Biotechnological Chondroitin 6-Sulphate for Prevention of Osteoarthritis
    Publication number: 20160074429
    Abstract: Disclosed is a low-molecular-weight (1000-5000 daltons) chondroitin sulphate (CS) produced by chemical sulphation and subsequent depolymerisation of a non-sulphated chondroitin backbone obtained with biotechnology techniques. The CS described is substantially monosulphated, mainly at the 6-position, with very little sulphation at the 4-position, and with a mono/disulphated disaccharide ratio and charge density similar to those of natural CS. Said biotechnological chondroitin 6-sulphate (C6S) is useful in the treatment and prevention of osteoarthritis and in acute and chronic inflammatory processes.
    Type: Application
    Filed: November 20, 2015
    Publication date: March 17, 2016
    Applicant: GNOSIS S.P.A.
    Inventors: Niccolo Miraglia, Davide Bianchi, Ermanno Valoti, Antonella Trentin, Antonio Trilli, Immacolata Busiello, Marco Agostinetto, Paola Bazza, Marco Valetti
  • Low-Molecular-Weight Biotechnological Chondroitin 6-Sulphate for Prevention of Osteoarthritis
    Publication number: 20150152198
    Abstract: Disclosed is a low-molecular-weight (1000-5000 daltons) chondroitin sulphate (CS) produced by chemical sulphation and subsequent depolymerisation of a non-sulphated chondroitin backbone obtained with biotechnology techniques. The CS described is substantially monosulphated, mainly at the 6-position, with very little sulphation at the 4-position, and with a mono/disulphated disaccharide ratio and charge density similar to those of natural CS. Said biotechnological chondroitin 6-sulphate (C6S) is useful in the treatment and prevention of osteoarthritis and in acute and chronic inflammatory processes.
    Type: Application
    Filed: May 22, 2013
    Publication date: June 4, 2015
    Inventors: Niccolo Miraglia, Davide Bianchi, Ermanno Valoti, Antonella Trentin, Antonio Trilli, Immacolata Busiello, Marco Agostinetto, Paola Bazza, Marco Valetti
  • FORMULATIONS CONTAINING SACCHAROMYCES BOULARDII AND SUPEROXIDE DISMUTASE (SOD) TO CONTROL OBESITY
    Publication number: 20140205581
    Abstract: Disclosed is a composition containing Saccharomyces cerevisiae var boulardii and the enzyme superoxide dismutase.
    Type: Application
    Filed: August 2, 2012
    Publication date: July 24, 2014
    Applicant: GNOSIS SPA
    Inventors: Ignazio Castagliuolo, Paola Brun, Immacolata Busiello, Niccolo Miraglia
  • Biotechnological production of chondroitin
    Patent number: 8771992
    Abstract: Chondroitin is produced by culturing a recombinant microorganism which is obtained by inactivation of a gene encoding an enzyme responsible for addition of fructose residues to the linear chondroitin polysaccharide in a microorganism producing a fructosylated derivative of chondroitin.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: July 8, 2014
    Assignee: GNOSIS S.p.A.
    Inventors: Antonio Trilli, Immacolata Busiello, Simona Daly, Francesca Bagatin
  • Biotechnological Production of Chondroitin
    Publication number: 20140073772
    Abstract: Chondroitin is produced by culturing a recombinant microorganism which is obtained by inactivation of a gene encoding an enzyme responsible for addition of fructose residues to the linear chondroitin polysaccharide in a microorganism producing a fructosylated derivative of chondroitin.
    Type: Application
    Filed: November 13, 2013
    Publication date: March 13, 2014
    Applicant: GNOSIS S.P.A.
    Inventors: Antonio Trilli, Immacolata Busiello, Simona Daly, Francesca Bagatin
  • Biotechnological production of chondroitin
    Patent number: 8609394
    Abstract: Chondroitin is produced by culturing a recombinant microorganism which is obtained by inactivation of a gene encoding an enzyme responsible for addition of fructose residues to the linear chondroitin polysaccharide in a microorganism producing a fructosylated derivative of chondroitin.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: December 17, 2013
    Assignee: Gnosis S.p.A.
    Inventors: Antonio Trilli, Immacolata Busiello, Simona Daly, Francesca Bagatin
  • Biotechnological Production of Chondroitin
    Publication number: 20120010399
    Abstract: Chondroitin is produced by culturing a recombinant microorganism which is obtained by inactivation of a gene encoding an enzyme responsible for addition of fructose residues to the linear chondroitin polysaccharide in a microorganism producing a fructosylated derivative of chondroitin.
    Type: Application
    Filed: June 24, 2011
    Publication date: January 12, 2012
    Applicant: GNOSIS S.P.A.
    Inventors: Antonio Trilli, Immacolata Busiello, Simona Daly, Francesca Bagatin