Patents by Inventor Immanuel Leuscher

Immanuel Leuscher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multicomponent conjugates which bind to target molecules and stimulate T cell lysis
    Publication number: 20070237771
    Abstract: The invention relates to immunoconjugates of formula: A-B—(C)n where B may be present or absent, A is a specific binding protein such as an antibody or an antibody binding fragment, or a ligand binding to a receptor present on target cells B comprises at least one molecule to which “A” and “C” bind, such as an avidin/streptavidin complex, “C” is an MHC molecule, and “n” is a whole number ranging from 1 to 10. The conjugates provide the exquisite binding specificity of antibodies, combined with an ability to stimulate cytotoxic T cells to identify and to destroy cells on which the conjugate is bound and oligomerized. The conjugates are useful both therapeutically and diagnostically.
    Type: Application
    Filed: May 21, 2007
    Publication date: October 11, 2007
    Inventors: Alena Donda, Jean-Pierre Mach, Valerie Cesson, Bruno Robert, Pedro Romero, Immanuel Leuscher, Philippe Guillaume
  • Multicomponent conjugates which bind to target molecules and stimulate T cell lysis
    Publication number: 20040143094
    Abstract: The invention relates to immunoconjugates of formula:
    Type: Application
    Filed: August 1, 2003
    Publication date: July 22, 2004
    Inventors: Alena Donda, Jean-Pierre Mach, Valerie Cesson, Bruno Robert, Pedro Romero, Immanuel Leuscher, Philippe Guillaume
  • Multicomponent conjugates which bind to target molecules and stimulate cell lysis
    Publication number: 20040068100
    Abstract: The invention relates to immunoconjugates of formula: A—B—(C)n where B may be present or absent, A is a specific binding protein such as an antibody or an antibody binding fragment, or a ligand binding to a receptor present on target cells, B comprises at least one molecule to which “A” and “C” bind, such as an avidin/strepavidin complex, “C” is an MHC molecule, and “n” is a whole number ranging from 1 to 10. The conjugates provide the exquisite binding specificity of antibodies, combined with an ability to stimulate cytotoxic T cells to identify and to destroy cells on which the conjugate is bound and oligomerized. The conjugates are useful both therapeutically and diagnostically.
    Type: Application
    Filed: February 10, 2003
    Publication date: April 8, 2004
    Inventors: Jean-Pierre Mach, Bruno Robert, Pedro Romero, Immanuel Leuscher, Philipped Guillaume