Abstract: An exemplary method includes, based on metrics available as input to a chronic phase optimization algorithm for selecting an optimal electrode configuration for delivery of a cardiac pacing therapy, executing the chronic phase optimization algorithm during an acute phase to select an optimal electrode configuration for delivery of a cardiac pacing therapy; during the acute phase, acquiring position information with respect to time for electrodes implanted in a body; determining one or more acute phase metrics based on the acquired position information; and validating the chronic phase optimization algorithm based at least in part on the one or more acute phase metrics.

Abstract: A catheter system suitable for introduction of a pacing lead into a branch of a human coronary sinus includes an outer, resilient catheter having shape memory which is configured for introduction into the coronary sinus from the right atrium of a human heart. The catheter has at least one preformed bend defining an acute included angle proximate a tip thereof, such that the catheter has a hooked end portion when in an undistorted condition. A stiff obturator is configured for sliding into and out of the catheter. A distal end portion of the obturator has a substantially straight configuration whereby introduction of the obturator fully into the catheter straightens the hooked end portion, and withdrawal of the obturator causes the hooked end portion to resume the hooked shape.