Patents by Inventor Imran R. Malik

Imran R. Malik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140057278
    Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a circular arrangement of containers, with a connecting structure such as a disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. The device may be pen-shaped and have a sample drawing needle connected to the containers.
    Type: Application
    Filed: November 1, 2013
    Publication date: February 27, 2014
    Applicant: California Institute Of Technology
    Inventors: Xiomara Linnette MADERO, Imran R MALIK, Erika F GARCIA, Axel SCHERER
  • Publication number: 20140057210
    Abstract: Methods to fabricate reaction cartridges for biological sample preparation and analysis are disclosed. A cartridge may have a reaction chamber and openings to allow fluids to enter the chamber. The cartridge may also have handles to facilitate its use. Such cartridges may be used for polymerase chain reaction.
    Type: Application
    Filed: November 1, 2013
    Publication date: February 27, 2014
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Imran R. MALIK, Axel SCHERER, Erika F. GARCIA, Xiomara L. MADERO
  • Publication number: 20140057277
    Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers.
    Type: Application
    Filed: November 1, 2013
    Publication date: February 27, 2014
    Applicant: California Institute Of Technology
    Inventors: Imran R MALIK, Erika F GARCIA, Xiomara Linnette MADERO, Axel SCHERER
  • Publication number: 20140057279
    Abstract: Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers. The device may have a reaction cartridge with a reaction chamber to perform techniques such as polymerase chain reaction.
    Type: Application
    Filed: November 1, 2013
    Publication date: February 27, 2014
    Applicant: California Institute Of Technology
    Inventors: Imran R. MALIK, Erika F. GARCIA, Xiomara Linnette MADERO, Axel SCHERER
  • Publication number: 20140038195
    Abstract: Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.
    Type: Application
    Filed: August 2, 2013
    Publication date: February 6, 2014
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Imran R. MALIK, Xiomara Linnette MADERO, Erika F. GARCIA, Sheel Mukesh SHAH, Axel SCHERER
  • Publication number: 20140036267
    Abstract: Structures and methods are described for optical detection of physical, chemical and/or biological samples. An optical detection structure may include a LED source, multiple filters and single or multiple sample areas. A detector may be used to record a fluorescence signal. The sample area may allow the introduction of removable cartridges.
    Type: Application
    Filed: July 22, 2013
    Publication date: February 6, 2014
    Inventors: Imran R. MALIK, Xiomara L. MADERO, Erika F. GARCIA, Axel SCHERER
  • Publication number: 20130164754
    Abstract: Devices and system for preparing samples are described. Such devices can comprise fluidic chambers, reservoirs, and movable structures for controlling the movement of samples. The device can also comprise functional elements for performing specific operations.
    Type: Application
    Filed: February 28, 2012
    Publication date: June 27, 2013
    Inventors: Imran R. MALIK, Axel SCHERER
  • Patent number: 8395773
    Abstract: Optical devices and methods for measuring samples while minimizing stray light are described. Such methods and devices are applicable to multiple fluid chambers with multiple sources as an integrated optical element. Light sources can be embedded onto a chip or microarray with multiple chambers, or can be part of an instrument arrangement.
    Type: Grant
    Filed: June 21, 2010
    Date of Patent: March 12, 2013
    Assignee: California Institute of Technology
    Inventors: Imran R. Malik, Axel Scherer
  • Publication number: 20120180882
    Abstract: A method of fabricating a fluidic device comprises providing a fluidic device including a body having a surface and one or more channels located in the body. Recesses are defined on said surface. The one or more channels can have respective boundaries. A layer of adhesive including one or more panel-shaped pieces having a pattern based on the pattern of boundaries of the channels can be formed and applied on the surface of the body. It is further controlled that the layer of adhesive has respective boundaries surrounding the boundaries of the one or more channels.
    Type: Application
    Filed: December 23, 2011
    Publication date: July 19, 2012
    Inventors: Imran R. MALIK, Axel SCHERER
  • Publication number: 20110207137
    Abstract: Methods for measuring and analyzing biological or chemical samples using consumer electronic devices and systems are described. Moreover, an accessory to enable using devices such as cell phones and smartphones with fluidic illumination chambers are described.
    Type: Application
    Filed: January 19, 2011
    Publication date: August 25, 2011
    Inventors: Imran R. MALIK, Axel Scherer
  • Publication number: 20100321696
    Abstract: Optical devices and methods for measuring samples while minimizing stray light are described. Such methods and devices are applicable to multiple fluid chambers with multiple sources as an integrated optical element. Light sources can be embedded onto a chip or microarray with multiple chambers, or can be part of an instrument arrangement.
    Type: Application
    Filed: June 21, 2010
    Publication date: December 23, 2010
    Inventors: Imran R. MALIK, Axel SCHERER
  • Publication number: 20100152066
    Abstract: Temperature control devices and methods are described. The described temperature control devices and methods comprise optical emission and detection assemblies and can be used in PCR and qPCR applications.
    Type: Application
    Filed: December 15, 2009
    Publication date: June 17, 2010
    Inventors: Imran R. MALIK, Axel Scherer