Patents by Inventor Imran Rashid

Imran Rashid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240138701
    Abstract: The technology relates to a method for detecting high-risk unstable atherosclerotic plaque in a subject, the method comprising: a) administering to the subject a magnetic resonance imaging (MRI) contrast agent capable of being activated by myeloperoxidase (MPO) in atherosclerotic plaque; b) allowing the contrast agent to be activated by myeloperoxidase in atherosclerotic plaque; c) obtaining an image of the atherosclerotic plaque from the subject using such molecular MRI, wherein enhanced imaging is indicative of unstable plaque. In some embodiments an MPO inhibitor is administered to a subject identified as having a high-risk unstable atherosclerotic plaque.
    Type: Application
    Filed: January 10, 2024
    Publication date: May 2, 2024
    Inventors: Roland STOCKER, Imran RASHID
  • Patent number: 11719778
    Abstract: Methods and systems generate synthetic late gadolinium enhancement (LGE) magnetic resonance images using a magnetic resonance fingerprinting (MRF) acquisition. From a single acquisition, MRF image data is obtained, including co-registered T1 and T2 tissue property maps. Different tissue regions of interest are identified, such as viable myocardium, scar, and blood and T1 and T2 values for each are determined. Based on these, different sets of pulse sequence parameters are determined, e.g., using different synthetic image contrast models receiving the MRF image data. Synthetic LGE images at different contrasts are generated as a result, including a synthetic bright-blood LGE image, a synthetic dark-blood/gray-blood LGE image, and a synthetic optimized imaged.
    Type: Grant
    Filed: January 31, 2022
    Date of Patent: August 8, 2023
    Assignees: REGENTS OF THE UNIVERSITY OF MICHIGAN, CASE WESTERN RESERVE UNIVERSITY, UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER
    Inventors: Jesse Hamilton, Imran Rashid, Nicole Seiberlich, Sanjay Rajagopalan
  • Publication number: 20230243909
    Abstract: Methods and systems generate synthetic late gadolinium enhancement (LGE) magnetic resonance images using a magnetic resonance fingerprinting (MRF) acquisition. From a single acquisition, MRF image data is obtained, including co-registered T1 and T2 tissue property maps. Different tissue regions of interest are identified, such as viable myocardium, scar, and blood and T1 and T2 values for each are determined. Based on these, different sets of pulse sequence parameters are determined, e.g., using different synthetic image contrast models receiving the MRF image data. Synthetic LGE images at different contrasts are generated as a result, including a synthetic bright-blood LGE image, a synthetic dark-blood/gray-blood LGE image, and a synthetic optimized imaged.
    Type: Application
    Filed: January 31, 2022
    Publication date: August 3, 2023
    Inventors: Jesse Hamilton, Imran Rashid, Nicole Seiberlich, Sanjay Rajagopalan
  • Publication number: 20210298611
    Abstract: The technology relates to a method for detecting high-risk unstable atherosclerotic plaque in a subject, the method comprising: a) administering to the subject a magnetic resonance imaging (MRI) contrast agent capable of being activated by myeloperoxidase (MPO) in atherosclerotic plaque; b) allowing the contrast agent to be activated by myeloperoxidase in atherosclerotic plaque; c) obtaining an image of the atherosclerotic plaque from the subject using such molecular MRI, wherein enhanced imaging is indicative of unstable plaque. In some embodiments an MPO inhibitor is administered to a subject identified as having a high-risk unstable atherosclerotic plaque.
    Type: Application
    Filed: July 25, 2019
    Publication date: September 30, 2021
    Inventors: Roland STOCKER, Imran RASHID
  • Patent number: D654263
    Type: Grant
    Filed: May 27, 2010
    Date of Patent: February 21, 2012
    Inventors: Tahir Mahmood, Imran Rashid