Patents by Inventor Imre Domán

Imre Domán has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of a 3(2H)-pyridazinone-4- substituted amino 5-chloro derivative
    Patent number: 6800758
    Abstract: The invention relates to novel processes for the preparation of 5-chloro-4-{3-[N-[2-(3,4-dimethoxyphenyl)-ethyl]-N-methylamino]-propylamino-3(2H) pyridazinone of formula (I) and the pharmaceutically acceptable acid addition salts thereof. An important feature of the invention is using 3,4,5-trichloropyridazone as starting substance of the synthesis.
    Type: Grant
    Filed: February 9, 2001
    Date of Patent: October 5, 2004
    Assignee: Egis Gyogyszergyar Rt.
    Inventors: Peter Kótay Nagy, Gyula Simig, József Barkóczy, Ilona Sztruhár, László Balázs, Imre Domán, Zoltán Greff, Zoltán Rátkai, Peter Seres, Támas Karancsi
  • Process for the preparation of amorphous atorvastatin calcium
    Publication number: 20040063969
    Abstract: A process is disclosed for the preparation of amorphous atorvastatin calcium which comprises dissolving crude atorvastatin calcium in a lower alkanol containing 2 to 4 carbon atoms or a mixture of such alkanols under heating and, after cooling, isolating the precipitated amorphous atorvastatin calcium.
    Type: Application
    Filed: October 20, 2003
    Publication date: April 1, 2004
    Applicant: EGIS GYOGYSZERGYAR RT.
    Inventors: Zoltan Greff, Peter Kotay Nagy, Jozsef Barkoczy, Gyula Simig, Laszlo Balazs, Imre Doman, Zoltan Ratkai, Peter Seres, Zsuzsa Szent Kirallyi, Ferenc Barta, Gyorgyi Vereczkeyne Donath, Kalman Nagy
  • Process for the preparation of amorphous atorvastatin calcium
    Patent number: 6646133
    Abstract: The invention relates to a process for the preparation of amorphous atorvastatin calcium by recrystallization of crude atorvastatin from an organic solvent which comprises dissolving crude amorphous atorvastatin calcium in a lower alkanol containing 2-4 carbon atoms or a mixture of such alkanols under heating and isolating the amorphous atorvastatin calcium precipitated after cooling. The atorvastatin calcium obtained is a known valuable agent useful in treating hyperlipidemia and hypercholestrolemia.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: November 11, 2003
    Assignee: Egis Gyogyszergyar Rt.
    Inventors: Zoltan Greff, Peter Kotay Nagy, Jozsef Barkoczy, Gyula Simig, Laszlo Balazs, Imre Doman, Zoltan Ratkai, Peter Seres, Zsuzsa Szent Kirallyi, Ferenc Barta, Gyorgyi Vereczkeyne Donath, Kalman Nagy
  • 8-substituted-9H-1,3-dioxolo/4,5-h//2,3/benzodiazepine derivatives, as AMPA/kainate receptor inhibitors
    Patent number: 6562810
    Abstract: The disclosure relates to a novel 8-substituted-9H-1,3-dioxolo-[4,5-h][2,3]benzodiazepine compound of formula I and pharmaceutically acceptable quaternary ammonium salts thereof, a process for preparing the same, a pharmaceutical composition containing a 8-substituted-9H-1,3-dioxolo-[4,5-h][2,3]benzodiazepine compound, and a method of treatment using the pharmaceutical composition. A complete description of the compound of formula I is found in the specification. The compounds of the general formula I possess unique competitive AMPA/kainite antagonist properties making them useful in the treatment of diseases where inhibition of the AMPA/kainite receptors may a favorable effect.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: May 13, 2003
    Assignee: Egis Gyogyszergyar RT.
    Inventors: László Balázs, József Barkóczy, Imre Domán, András Egyed, Istvän Gacsályi, Gábor Gigler, Zoltán Greff, István Gyertyán, Péter Kótay Nagy, Attila Kovács, György Lávay, Zoltán Rátkai, Péter Seres, Gyula Simig, Annamária Simó, Tamás Szabados, Géza Szabó, Károly Tihanyi, Miklós Végh, Géza Schneider, Judit Cselenyák
  • Heterocyclic compounds, pharmaceutical compositions comprising them and process for the preparation thereof
    Patent number: 5889018
    Abstract: The invention relates to anxiolytic pharmaceutical compositions comprising as active ingredient 1-sytrylisoquinoline derivatives of general formula (I), whereinn is 1, 2, 3 or 4;R may be the same or different and represent(s) hydrogen, lower alkyl, lower alkoxy or hydroxy, or two substituents R attached to adjacent carbon atoms may form together an alkylenedioxy group;R.sup.1 represents hydrogen or lower alkyl, andAr stands for an optionally substituted aryl or heteroaryl,Some of the compounds of general formula (I) is known, but the majority thereof has not so far described in the literature.The invention also encompasses the preparation of the new compounds of general formula (I), which comprises reacting a compound of general formula (II) with an aldehyde or general formula (III) in the presence of a condensing agent or an acidic catalyst.
    Type: Grant
    Filed: May 3, 1995
    Date of Patent: March 30, 1999
    Assignee: Egis Gyogyszergyar RT.
    Inventors: Gyula Balogh, deceased, Imre Doman, Gabor Blasko, Gyula Simig, Erzsebet Kovacs nee Kaszab, Istvan Gyertyan, Andras Egyed, Istvan Gacsalyi, Andras Bilkei-Gorzo, Katalin Pallagi, Katalin Szemeredi, Klara Kazo nee Daroczi