Patents by Inventor Imre Noth

Imre Noth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR PREDICTING LUNG FUNCTION DECLINE IN IDIOPATHIC PULMONARY FIBROSIS
    Publication number: 20220291231
    Abstract: Provided are methods for generating prognostic signatures for subject diagnosed with Idiopathic Pulmonary Fibrosis (IPF) with respect to decline in lung Forced Vital Capacity (FVC). The methods can include determining first expression levels for one or more genes as set forth herein in a first biological sample obtained from a subject diagnosed with IPF, determining a second expression level for the same one or more genes in a second biological sample obtained from the subject, and comparing the first and second expression levels for the one or more genes to provide a prognostic signature. The first and second biological samples can include peripheral blood mononuclear cells (PBMCs) and/or nucleic acids extracted from PBMCs. Also provided are methods for classifying subjects with IPF as being at risk for FVC decline, for identifying and treating at risk subjects, and for monitoring the progress of treatments.
    Type: Application
    Filed: January 13, 2020
    Publication date: September 15, 2022
    Inventor: Imre Noth
  • BIOMARKERS FOR ASSESSING IDIOPATHIC PULMONARY FIBROSIS
    Publication number: 20220235417
    Abstract: Disclosed are methods and kits for evaluating predicting whether an individual IPF has slowly or rapidly progressive IPF.
    Type: Application
    Filed: March 29, 2021
    Publication date: July 28, 2022
    Applicants: The University of Chicago, The Board of Trustees of the University of Illinois, University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Imre Noth, Yong Huang, Jose David Herazo-Maya, Naftali Kaminski, Kevin Gibson, Joe G.N. Garcia
  • Biomarkers for assessing idiopathic pulmonary fibrosis
    Patent number: 10961582
    Abstract: Disclosed are methods and kits for evaluating predicting whether an individual IPF has slowly or rapidly progressive IPF.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: March 30, 2021
    Assignees: The University of Chicago, The Board of Trustees of the University of Illinois, University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Imre Noth, Yong Huang, Jose David Herazo-Maya, Naftali Kaminski, Kevin Gibson, Joe G. N. Garcia
  • METHOD FOR TREATING IDIOPATHIC PULMONARY FIBROSIS
    Publication number: 20200155494
    Abstract: Aspects of the disclosure relate to a method for treating idiopathic pulmonary fibrosis (IPF) in a patient with N-acetylcysteine (NAC) comprising administering NAC to a patient after a sample from the patient has been genotyped and determined to be any one of: a) homozygous or heterozygous for a thymine at the single nucleotide polymorphism rs3750920; b) homozygous or heterozygous for guanine at the single nucleotide polymorphism rs5743894; or c) homozygous or heterozygous for thymine at the single nucleotide polymorphism rs35705950.
    Type: Application
    Filed: January 16, 2020
    Publication date: May 21, 2020
    Inventors: Imre Noth, Ustin Oldham, Fernando Martinez
  • Method for treating idiopathic pulmonary fibrosis
    Patent number: 10543185
    Abstract: Aspects of the disclosure relate to a method for treating idiopathic pulmonary fibrosis (IPF) in a patient with N-acetylcysteine (NAC) comprising administering NAC to a patient after a sample from the patient has been genotyped and determined to be any one of: a) homozygous or heterozygous for a thymine at the single nucleotide polymorphism rs3750920; b) homozygous or heterozygous for guanine at the single nucleotide polymorphism rs5743894; or c) homozygous or heterozygous for thymine at the single nucleotide polymorphism rs35705950.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: January 28, 2020
    Assignees: The University of Chicago, Cornell University
    Inventors: Imre Noth, Justin Oldham, Fernando Martinez
  • BIOMARKERS FOR ASSESSING IDIOPATHIC PULMONARY FIBROSIS
    Publication number: 20180320234
    Abstract: Disclosed are methods and kits for evaluating predicting whether an individual IPF has slowly or rapidly progressive IPF.
    Type: Application
    Filed: July 10, 2018
    Publication date: November 8, 2018
    Inventors: Imre Noth, Yong Huang, Jose David Herazo-Maya, Naftali Kaminski, Kevin Gibson, Joe G.N. Garcia
  • Biomarkers for assessing idiopathic pulmonary fibrosis
    Patent number: 10036069
    Abstract: Disclosed are methods are kits for evaluating predicting whether an individual IPF has slowly or rapidly progressive IPF.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: July 31, 2018
    Assignees: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, THE UNIVERSITY OF CHICAGO, THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Imre Noth, Yong Huang, Jose David Herazo-Maya, Naftali Kaminski, Kevin Gibson, Joe G. N. Garcia
  • METHOD FOR TREATING IDIOPATHIC PULMONARY FIBROSIS
    Publication number: 20180133184
    Abstract: Aspects of the disclosure relate to a method for treating idiopathic pulmonary fibrosis (IPF) in a patient with N-acetylcysteine (NAC) comprising administering NAC to a patient after a sample from the patient has been genotyped and determined to be any one of: a) homozygous or heterozygous for a thymine at the single nucleotide polymorphism rs3750920; b) homozygous or Cheterozygous for guanine at the single nucleotide polymorphism rs5743894; or c) homozygous or heterozygous for thymine at the single nucleotide polymorphism rs35705950.
    Type: Application
    Filed: April 20, 2016
    Publication date: May 17, 2018
    Inventors: Imre Noth, Justin Oldham, Fernando Martinez
  • Marker Panels For Idiopathic Pulmonary Fibrosis Diagnosis And Evaluation
    Publication number: 20140335547
    Abstract: The present invention relates to the discovery that of a panel of serum or plasma markers may be used to diagnose Idiopathic Pulmonary Fibrosis (“IPF”) and distinguish this condition from other lung ailments. It further relates to the identification of markers associated with IPF disease progression.
    Type: Application
    Filed: May 14, 2014
    Publication date: November 13, 2014
    Applicants: Instituto Nacional De Enfermedades Respiratorias Ismael Cosio Villegas, United States Of America, Secretary, Dept. Of Health And Human Services, The University Of Chicago, University Of Pittsburgh - Of The Commonwealth System Of Higher Education
    Inventors: Naftali Kaminski, Kevin F. Gibson, Bernadette R. Gochuico, Thomas J. Richards, Ivan Rosas, Kazuhisa Konishi, Moises Selman, Jose David Herazo-Maya, Imre Noth
  • BIOMARKERS FOR ASSESSING IDIOPATHIC PULMONARY FIBROSIS
    Publication number: 20140323343
    Abstract: Disclosed are methods are kits for evaluating predicting whether an individual IPF has slowly or rapidly progressive IPF.
    Type: Application
    Filed: November 16, 2012
    Publication date: October 30, 2014
    Applicant: University of Chicago
    Inventors: Imre Noth, Yong Huang, Jose David Herazo-Maya, Naftali Kaminski, Kevin Gibson, Joe G.N. Garcia
  • Marker panels for idiopathic pulmonary fibrosis diagnosis and evaluation
    Patent number: 8846341
    Abstract: The present invention relates to the discovery that of a panel of serum or plasma markers may be used to diagnose Idiopathic Pulmonary Fibrosis (“IPF”) and distinguish this condition from other lung ailments. It further relates to the identification of markers associated with IPF disease progression.
    Type: Grant
    Filed: March 3, 2011
    Date of Patent: September 30, 2014
    Assignees: University of Pittsburgh—of the Commonwealth System of Higher Education, The University of Chicago, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas—D.F.
    Inventors: Naftali Kaminski, Kevin F. Gibson, Bernadette R. Gochuico, Thomas J. Richards, Ivan Rosas, Kazuhisa Konishi, Moises Selman, Jose David Herazo-Maya, Imre Noth
  • Marker Panels For Idiopathic Pulmonary Fibrosis Diagnosis And Evaluation
    Publication number: 20120035067
    Abstract: The present invention relates to the discovery that of a panel of serum or plasma markers may be used to diagnose Idiopathic Pulmonary Fibrosis (“IPF”) and distinguish this condition from other lung ailments. It further relates to the identification of markers associated with IPF disease progression.
    Type: Application
    Filed: March 3, 2011
    Publication date: February 9, 2012
    Inventors: Naftali Kaminski, Kevin F. Gibson, Bernadette R. Gochuico, Thomas J. Richards, Ivan Rosas, Kazuhisa Konishi, Moises Selman, Jose David Herrazo-Maya, Imre Noth
  • Nebulized pharmaceutical compositions for the treatment of bronchial disorders
    Publication number: 20060014698
    Abstract: The present invention provides methods and pharmaceutical compositions for the treatment of bronchial disorders by inhalation therapy. In various embodiments, the active ingredient of the pharmaceutical compositions is one or more of a sulfated pentasaccharide and a peptidomemtic of a tripeptide. In various embodiments, the active ingredient of the pharmaceutical compositions is one or more of argatroban and fondaparinux.
    Type: Application
    Filed: July 14, 2005
    Publication date: January 19, 2006
    Inventors: Michael O'Connor, Edward Naureckas, Imre Noth