Abstract: A mattress assembly includes: multiple gas-filled chambers each having a top surface, the top surfaces of the chambers collectively composing a top surface of the mattress assembly; multiple composite sensors each associated with a corresponding chamber. Each composite sensor includes a pressure sensor to measure a pressure at a wall of the corresponding chamber and a temperature sensor to measure a temperature of the corresponding chamber. The assembly includes chamber regulators each in communication with a corresponding chamber, each regulator configured to pump gas at a first, higher temperature and gas at a second temperature to the corresponding chamber.

Abstract: The present invention provides a method for the synthesis of an injectable composition comprising a [18F]-labelled pyridaben derivative that is amenable to automation. In particular, the method of the present invention comprises a method of purification carried out by means of solid phase extraction (SPE) alone.

Abstract: The present invention provides a method for the synthesis of an injectable composition comprising a [18F]-labelled pyridaben derivative that is amenable to automation. In particular, the method of the present invention comprises a method of purification carried out by means of solid phase extraction (SPE) alone.

Abstract: The invention relates to a method of preparing an [18F] radio-labelled compound, wherein the water content is controlled. Controlling the water content and the origin of the water within the reaction process has a significant effect on both the yield and the purity of the product of the radio-labelling process.

Abstract: Provided is a method of preparing an aqueous ascorbic acid solution having a pH of 2.0 to 4.0, the method comprising: providing an initial aqueous solution of ascorbic acid and a base, wherein the initial solution has a pH of 5.0 to 8.0; and combining the initial solution with a second acid to obtain an ascorbic acid solution having a pH of 2.0 to 4.0. Also provided is the use of an aqueous ascorbic acid solution having a pH of 2.0 to 4.0 prepared by a described method as a radiostabiliser of a radio-labelled compound.

Abstract: The present invention concerns a HPLC separation method useful in the synthesis of [18F]-labelled compounds, including positron emission tomography (PET) tracers. The method of the invention addresses constraints of previous methods imposed by the needs of free 5 [18F]fluoride. The present invention provides a simplified process that enables rapid separation and analysis of free [18F]fluoride and chemical impurities in the synthesis of [18F]-labelled compounds.

Abstract: A method for monitoring a flowrate of cerebrospinal fluid (CSF) in a ventriculo-peritoneal (VP) shunt implanted in a human patient includes: (i) receiving, at a device external to the human patient, data sensed by a plurality of sensors within the device and positioned relative to the VP shunt to drain excess cerebrospinal fluid from the human patient's brain; (2) determining, by the device and based on the sensed data, a rate of flow of the CSF in the VP shunt; and (3) transmitting (e.g., wirelessly), by the device, data indicating the rate of flow to a computing server.

Abstract: A sensor device is described that includes a dry electrode, a pressure sensor, and a communication apparatus. The dry electrode is configured to be placed adjacent to a belly of a pregnant patient. The pressure sensor is coupled to the dry electrode to sense pressure within the belly. The sensed pressure indicates counts of physiological activities of a fetus within the pregnant patient over a period of time. The communication apparatus is coupled to the pressure sensor and the dry electrode. The communication apparatus is configured to transmit data characterizing the counts of the plurality of physiological activities to a cloud computing server for generating an assessment of health of the fetus.

Abstract: A resuscitation device is described that can include an electronic circuit board, a shaft that is operably coupled with the electronic circuit board and has a head, a gas-bag adjacent to the head and configured to store gas, and a valve operably coupled to the gas-bag. The electronic circuit board can actuate the shaft to move. The moving of the shaft can cause the head to compress the gas-bag. The compression of the gas-bag can cause the gas-bag to release gas. Related apparatuses, systems, methods, techniques and articles are also described.

Abstract: It is provided a process of converting syngas resulting from the gasification of a carbonaceous material into acetic acid and acrylic acid comprising converting the syngas into methanol and separating the methanol into a first and second stream, carbonylation of the first stream of methanol producing methyl acetate, hydrolyzing the methyl acetate to obtain acetic acid, oxidizing the second stream of the methanol into formaldehyde in a gas phase reaction, and reacting by aldol condensation the formaldehyde and acetic acid to produce acrylic acid. Particularly, the first stream of methanol is dehydrated to produce dimethyl ether (DME) and the DME is further contacted with syngas under an iodide-free environment to produce the methyl acetate by carbonylation, and subsequently acetic acid using a reactive distillation column.

Abstract: A positioning device includes a base extending in a horizontal plane, a support post extending along a vertical axis, a detachable headrest subassembly attached to an end of the support post opposite the base, an arm rest subassembly attached to the support post between the headrest subassembly and the base, a thoracic support subassembly attached to the support post between the armrest subassembly and the base, A thoracic support cushion is attached to the support post by a bar. The attachment is reconfigurable to vary an orientation and location of the cushion with respect to the vertical axis, a footrest subassembly attached to the support post between the thoracic support subassembly and the base, and a digital device holder attached to the positioned device by a flexible arm, the flexible arm configured to support a digital device in view of the patient during use of the positioning device.

Abstract: A device is described that can include a probe, a mobile device, and at least one processor. The probe can examine a corresponding anatomical part of a body. The mobile device can have a camera to take an image of the anatomical part of the body. The mobile device can execute a patient-application to process the image. The at least one processor can be configured to transmit the processed image to a server via a communication network. Related apparatuses, systems, methods, techniques and articles are also described.

Abstract: The present invention provides a method for the synthesis of an injectable composition comprising a [18F]-labelled pyridaben derivative that is advantageous over prior methods. In particular, the method of the present invention comprises a method of radiosynthesis that permits a more facile purification using solid phase extraction (SPE).

Abstract: The present invention provides a method for the synthesis of an injectable composition comprising a [18F]-labelled pyridaben derivative that is advantageous over prior methods. In particular, the method of the present invention comprises a method of radiosynthesis that permits a more facile purification using solid phase extraction (SPE).

Abstract: The present invention provides a cassette for determining optimised solid phase extraction (SPE) purification conditions, wherein said cassette comprises: (i) a flowpath comprising a first end and a second end; and (ii) a plurality of valves oriented along said flowpath, wherein each of said plurality of valves is selectively fluidly connected to one of a number of components, wherein said components comprise: (a) 1-5 composition vials; (b) 1-3 SPE cartridges; (c) 4-10 solvent vials; (d) a water vial; and (e) a transfer line.

Abstract: An electrocardiography device is described that can include a main body, an adjustable cap, and a power switch. The main body can include an electrode of a plurality of electrodes configured to acquire electrical signal from a patient. The adjustable cap can include two electrodes of the plurality of electrodes. The adjustable cap can be rotatable around an axis on the main body to orient the plurality of electrodes on different locations on a body of the patient. The power switch can activate the plurality of electrodes to acquire the electrical signal from the patient. Related apparatuses, systems, methods, techniques and articles are also described.

Abstract: A method for monitoring a flowrate of cerebrospinal fluid (CSF) in a ventriculo-peritoneal (VP) shunt implanted in a human patient includes: (i) receiving, at a device external to the human patient, data sensed by a plurality of sensors within the device and positioned relative to the VP shunt to drain excess cerebrospinal fluid from the human patient's brain; (2) determining, by the device and based on the sensed data, a rate of flow of the CSF in the VP shunt; and (3) transmitting (e.g., wirelessly), by the device, data indicating the rate of flow to a computing server.

Abstract: The present invention provides a radiopharmaceutical composition comprising the following four components: (i) a radio-labelled compound; (ii) ethanol; (iii) a stabilizer of the radio-labelled compound; and (iv) a cyclodextrin. The present invention also provides a radiopharmaceutical composition comprising: (i) a radio-labelled compound; (ii) a stabilizer of the radio-labelled compound, wherein the stabilizer comprises: ascorbic acid, aspartic acid, cysteine, maleic acid, gentisic acid, glutathione, glutamic acid, mannitol, nicotinamide, calcium chloride, N-t-butyl-alpha-phenylnitrone (PBN), tartaric acid, para-aminobenzoic acid (pABA), chloride ions or salts or combinations thereof; and (iii) a cyclodextrin.

Abstract: Disclosed herein is a system, including a mobile device; a sensor module attached to the mobile device, the sensor module including a temperature sensor, an infrared sensor, at least one conductance sensor, and at least one electromyography sensor; and an application installed on the mobile device, wherein during operation the application causes the mobile device to receive data from one or more of the temperature sensor, the infrared sensor, the at least one conductance sensor, and the at least one electromyography sensor, and to determine information about a stress level of a human subject based on the received data.

Abstract: A mattress assembly includes: multiple gas-filled chambers each having a top surface, the top surfaces of the chambers collectively composing a top surface of the mattress assembly; multiple composite sensors each associated with a corresponding chamber. Each composite sensor includes a pressure sensor to measure a pressure at a wall of the corresponding chamber and a temperature sensor to measure a temperature of the corresponding chamber. The assembly includes chamber regulators each in communication with a corresponding chamber, each regulator configured to pump gas at a first, higher temperature and gas at a second temperature to the corresponding chamber.