Patents by Inventor IMTIAZ Ahmed KHAN

IMTIAZ Ahmed KHAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilized radiolabelling reaction
    Patent number: 11565257
    Abstract: The present invention provides a method for the synthesis of an injectable composition comprising a [18F]-labelled pyridaben derivative that is advantageous over prior methods. In particular, the method of the present invention comprises a method of radiosynthesis that permits a more facile purification using solid phase extraction (SPE).
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: January 31, 2023
    Assignee: GE HEALTHCARE LIMITED
    Inventors: Torgrim Engell, Alexander Jackson, Imtiaz Ahmed Khan, Alan Peter Clarke, Graeme McRobbie, Julian Grigg
  • APPARATUS AND METHOD FOR SOLID PHASE EXTRACTION
    Publication number: 20230022430
    Abstract: The present invention provides a cassette for determining optimised solid phase extraction (SPE) purification conditions, wherein said cassette comprises: (i) a flowpath comprising a first end and a second end; and (ii) a plurality of valves oriented along said flowpath, wherein each of said plurality of valves is selectively fluidly connected to one of a number of components, wherein said components comprise: (a) 1-5 composition vials; (b) 1-3 SPE cartridges; (c) 4-10 solvent vials; (d) a water vial; and (e) a transfer line.
    Type: Application
    Filed: December 17, 2020
    Publication date: January 26, 2023
    Applicant: GE HEALTHCARE LIMITED
    Inventors: Graeme Walter MCROBBIE, Imtiaz Ahmed Khan, Jonathan Robert SHALES
  • RADIOTRACER COMPOSITIONS AND METHODS
    Publication number: 20220202965
    Abstract: The present invention relates to the field of radiopharmaceuticals for in vivo imaging, in particular to radiotracer compositions which comprises 18F-labelled c-Met binding peptides. The invention provides said compositions, as well as associated automated methods of preparation and cassettes.
    Type: Application
    Filed: March 15, 2022
    Publication date: June 30, 2022
    Inventors: Torgrim ENGELL, Gareth Simon GETVOLDSEN, Andreas Richard MEIJER, Imtiaz Ahmed KHAN, Graeme MCROBBIE, Robert James NAIRNE
  • Radiotracer compositions and methods
    Patent number: 11311636
    Abstract: The present invention relates to the field of radiopharmaceuticals for in vivo imaging, in particular to radiotracer compositions which comprises 18F-labelled c-Met binding peptides. The invention provides said compositions, as well as associated automated methods of preparation and cassettes.
    Type: Grant
    Filed: April 4, 2019
    Date of Patent: April 26, 2022
    Assignee: GE HEALTHCARE LIMITED
    Inventors: Torgrim Engell, Gareth Simon Getvoldsen, Andreas Richard Meijer, Imtiaz Ahmed Khan, Graeme McRobbie, Robert James Nairne
  • RADIOTRACER COMPOSITIONS AND METHODS
    Publication number: 20190275182
    Abstract: The present invention relates to the field of radiopharmaceuticals for in vivo imaging, in particular to radiotracer compositions which comprises 18F-labelled c-Met binding peptides. The invention provides said compositions, as well as associated automated methods of preparation and cassettes.
    Type: Application
    Filed: April 4, 2019
    Publication date: September 12, 2019
    Inventors: Torgrim ENGELL, Gareth Simon GETVOLDSEN, Andreas Richard MEIJER, Imtiaz Ahmed KHAN, Graeme MCROBBIE, Robert James NAIRNE
  • Radiotracer compositions and methods
    Patent number: 10300156
    Abstract: The present invention relates to the field of radiopharmaceuticals for in vivo imaging, in particular to radiotracer compositions which comprises 18F-labelled c-Met binding peptides. The invention provides said compositions, as well as associated automated methods of preparation and cassettes.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: May 28, 2019
    Assignee: GE Healthcare Limited
    Inventors: Torgrim Engell, Gareth Simon Getvoldsen, Andreas Richard Meijer, Imtiaz Ahmed Khan, Robert James Nairne, Graeme McRobbie
  • Radiolabelling method
    Patent number: 10220105
    Abstract: The present invention relates to the field of radiopharmaceuticals for in vivo imaging, in particular to automated methods for the preparation and purification of 18F-labelled tau imaging radiotracers. Also provided are interchangeable cassettes useful in the methods, and the use of automated synthesizers and cassettes in the methods.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: March 5, 2019
    Assignee: GE HEALTHCARE LIMITED
    Inventors: Duncan George Wynn, Steven Michael Fairway, Matthias Eberhard Glaser, Ian Newington, Gareth Edwin Smith, Imtiaz Ahmed Khan, Julian Grigg
  • RADIOLABELLING METHOD
    Publication number: 20170106104
    Abstract: The present invention relates to the field of radiopharmaceuticals for in vivo imaging, in particular to automated methods for the preparation and purification of 18F-labelled tau imaging radiotracers. Also provided are interchangeable cassettes useful in the methods, and the use of automated synthesizers and cassettes in the methods.
    Type: Application
    Filed: December 16, 2014
    Publication date: April 20, 2017
    Inventors: Duncan George Wynn, Steven Michael Fairway, Matthias Eberhard Glaser, Ian NEWINGTON, Gareth Edwin Smith, IMTIAZ Ahmed KHAN, Julian Grigg
  • RADIOTRACER COMPOSITIONS AND METHODS
    Publication number: 20160303263
    Abstract: The present invention relates to the field of radiopharmaceuticals for in vivo imaging, in particular to radiotracer compositions which comprises 18F-labelled c-Met binding peptides. The invention provides said compositions, as well as associated automated methods of preparation and cassettes.
    Type: Application
    Filed: December 18, 2014
    Publication date: October 20, 2016
    Inventors: Torgrim Engell, Gareth Simon Getvoldsen, Andreas Richard Meijer, IMTIAZ Ahmed KHAN, Robert James Nairne, Graeme McRobbie
  • PURIFICATION METHOD AND COMPOSITIONS
    Publication number: 20160303262
    Abstract: The present invention relates to the field of radiopharmaceuticals for in vivo imaging, in particular to a method of purifying a radiotracer which comprises 18F-labelled aminoxy-functionalised biological targeting moiety. The invention provides radioprotectant-containing radiopharmaceutical compositions of the tracers, as well as associated automated methods and cassettes.
    Type: Application
    Filed: December 18, 2014
    Publication date: October 20, 2016
    Applicant: GE HEALTHCARE LIMITED
    Inventors: Torgrim Engell, Andreas Richard Meijer, IMTIAZ Ahmed KHAN, Robert James Nairne, Graeme McRobbie