Patents by Inventor In Geun Jo

In Geun Jo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for synthesizing 3-phenyl-2,8-dihydropyrano [2,3-f] chromene derivative
    Patent number: 11420978
    Abstract: The present invention relates to a method for synthesizing a 3-phenyl-2,8-dihydropyrano[2,3-f]chromene derivative, which may be usefully used for synthesizing a pyranochromenyl phenol derivative, and when the derivative is used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative may be effectively prepared.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: August 23, 2022
    Inventors: Sang Ku Yoo, Jin Wook Chung, In Geun Jo, Ji Young Kim, Jeong Ho Im, Ku Suk Kang, Jin Young Kim
  • PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROLOGICAL DISEASES
    Publication number: 20220257557
    Abstract: The present disclosure relates to a pharmaceutical composition for preventing or treating neurological disease containing a pyrano[2,3-f]chromene derivative compound, a pharmaceutically acceptable salt thereof, or a solvate thereof. The pharmaceutical composition is capable of enhancing or protecting the functions of various enzymes including paraoxonase.
    Type: Application
    Filed: February 28, 2020
    Publication date: August 18, 2022
    Inventors: SANG KU YOO, JI YOUNG KIM, IN GEUN JO, KYUNG IL KIM, YUN SUN PARK
  • Optically active pyranochromenyl phenol derivative and pharmaceutical composition comprising same
    Patent number: 11332475
    Abstract: The present invention relates to pyranochromenylphenol derivatives having different efficacies depending on the direction of optical activity and a pharmaceutical composition including the same, and in the pyranochromenylphenol derivatives, an R-enantiomer has excellent anti-diabetic efficacy by suppressing a rise in blood sugar and an S-enantiomer has excellent anti-obesity efficacy by suppressing an increase in body weight.
    Type: Grant
    Filed: December 8, 2020
    Date of Patent: May 17, 2022
    Inventors: Sang Ku Yoo, Jin Wook Chung, In Geun Jo, Ji Young Kim, Jeong Ho Im, Ku Suk Kang, Jin Young Kim
  • OPTICALLY ACTIVE PYRANOCHROMENYL PHENOL DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
    Publication number: 20210094967
    Abstract: The present invention relates to pyranochromenylphenol derivatives having different efficacies depending on the direction of optical activity and a pharmaceutical composition including the same, and in the pyranochromenylphenol derivatives, an R-enantiomer has excellent anti-diabetic efficacy by suppressing a rise in blood sugar and an S-enantiomer has excellent anti-obesity efficacy by suppressing an increase in body weight.
    Type: Application
    Filed: December 8, 2020
    Publication date: April 1, 2021
    Inventors: SANG KU YOO, JIN WOOK CHUNG, IN GEUN JO, Jl YOUNG KIM, JEONG HO IM, KU SUK KANG, JIN YOUNG KIM
  • 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and method for synthesizing optical isomer thereof
    Patent number: 10947250
    Abstract: The present invention relates to a method for synthesizing a 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and an optical isomer thereof, and an intermediate Compound which may be used for the synthesis method, and when the method and the intermediate Compound are used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and the optical isomer thereof may be effectively synthesized.
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: March 16, 2021
    Inventors: Sang Ku Yoo, Jin Wook Chung, In Geun Jo, Ji Young Kim, Jeong Ho Im, Ku Suk Kang, Jin Young Kim
  • METHOD FOR SYNTHESIZING 3-PHENYL-2,8-DIHYDROPYRANO [2,3-F] CHROMENE DERIVATIVE
    Publication number: 20210040106
    Abstract: The present invention relates to a method for synthesizing a 3-phenyl-2,8-dihydropyrano[2,3-f]chromene derivative, which may be usefully used for synthesizing a pyranochromenyl phenol derivative, and when the derivative is used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative may be effectively prepared.
    Type: Application
    Filed: April 3, 2019
    Publication date: February 11, 2021
    Applicant: GLACEUM INC.
    Inventors: Sang Ku YOO, Jin Wook CHUNG, In Geun JO, Ji Young KIM, Jeong Ho IM, Ku Suk KANG, Jin Young KIM
  • 3-PHENYL-2,3,4,8,9,10-HEXAHYDROPYRANO[2,3-F]CHROMENE DERIVATIVE AND METHOD FOR SYNTHESIZING OPTICAL ISOMER THEREOF
    Publication number: 20200199142
    Abstract: The present invention relates to a method for synthesizing a 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and an optical isomer thereof, and an intermediate Compound which may be used for the synthesis method, and when the method and the intermediate Compound are used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and the optical isomer thereof may be effectively synthesized.
    Type: Application
    Filed: March 3, 2020
    Publication date: June 25, 2020
    Inventors: SANG KU YOO, JIN WOOK CHUNG, IN GEUN JO, JI YOUNG KIM, JEONG HO IM, KU SUK KANG, JIN YOUNG KIM
  • Method for synthesizing 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2.3-f]chromene derivative and optical isomer of thereof
    Patent number: 10669282
    Abstract: The present invention relates to a method for synthesizing a 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and an optical isomer thereof, and an intermediate Compound which may be used for the synthesis method, and when the method and the intermediate Compound are used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and the optical isomer thereof may be effectively synthesized.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: June 2, 2020
    Assignee: GLACEUM, INC.
    Inventors: Sang Ku Yoo, Jin Wook Chung, In Geun Jo, Ji Young Kim, Jeong Ho Im, Ku Suk Kang, Jin Young Kim
  • 3-PHENYL-2,3,4,8,9,10-HEXAHYDROPYRANO[2,3-F]CHROMENE DERIVATIVE AND METHOD FOR SYNTHESIZING OPTICAL ISOMER THEREOF
    Publication number: 20200048272
    Abstract: The present invention relates to a method for synthesizing a 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and an optical isomer thereof, and an intermediate Compound which may be used for the synthesis method, and when the method and the intermediate Compound are used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and the optical isomer thereof may be effectively synthesized.
    Type: Application
    Filed: September 27, 2017
    Publication date: February 13, 2020
    Applicant: Glaceum, Inc.
    Inventors: Sang Ku YOO, Jin Wook CHUNG, In Geun JO, Ji Young KIM, Jeong Ho IM, Ku Suk KANG, Jin Young KIM
  • OPTICALLY ACTIVE PYRANOCHROMENYL PHENOL DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
    Publication number: 20190152984
    Abstract: The present invention relates to pyranochromenylphenol derivatives having different efficacies depending on the direction of optical activity and a pharmaceutical composition including the same, and in the pyranochromenylphenol derivatives, an R-enantiomer has excellent anti-diabetic efficacy by suppressing a rise in blood sugar and an S-enantiomer has excellent anti-obesity efficacy by suppressing an increase in body weight.
    Type: Application
    Filed: June 29, 2017
    Publication date: May 23, 2019
    Inventors: SANG KU YOO, JIN WOOK CHUNG, IN GEUN JO, Jl YOUNG KIM, JEONG HO IM, KU SUK KANG, JIN YOUNG KIM
  • Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease
    Patent number: 9783551
    Abstract: Provided are a pyranochromenyl phenol derivative, a pharmaceutically acceptable salt thereof, or a solvate thereof. Also provided is a pharmaceutical composition for preventing or treating metabolic syndrome or inflammatory disease comprising same. The present invention is efficacious in preventing or treating metabolic syndrome or inflammatory disease and is chemically stable.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: October 10, 2017
    Assignee: Glaceum Inc.
    Inventors: Sang Ku Yoo, Jin Wook Chung, In Geun Jo, Jeong Ho Im, Ku Suk Kang, Jin Young Kim
  • PYRANOCHROMENYL PHENOL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR TREATING METABOLIC SYNDROME OR INFLAMMATORY DISEASE
    Publication number: 20160272650
    Abstract: Provided are a pyranochromenyl phenol derivative, a pharmaceutically acceptable salt thereof, or a solvate thereof. Also provided is a pharmaceutical composition for preventing or treating metabolic syndrome or inflammatory disease comprising same. The present invention is efficacious in preventing or treating metabolic syndrome or inflammatory disease and is chemically stable.
    Type: Application
    Filed: December 23, 2014
    Publication date: September 22, 2016
    Applicant: ERUM BIOTECHNOLOGIES, INC.
    Inventors: Sang Ku YOO, Jin Wook CHUNG, In Geun JO, Jeong Ho IM, Ku Suk KANG, Jin Young KIM
  • Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases
    Patent number: 9066922
    Abstract: Provided is a pharmaceutical composition for the treatment and prevention of obesity, diabetes, metabolic syndromes, degenerative diseases and mitochondrial dysfunction-related diseases, comprising: a therapeutically effective amount of a compound represented by Formula I below, or a pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, and a pharmaceutically acceptable carrier, a diluent or an excipient, or any combination thereof. wherein R1 through R8 and n are as defined in this disclosure.
    Type: Grant
    Filed: April 25, 2013
    Date of Patent: June 30, 2015
    Assignees: MD BIOALPHA CO., LTD., KT & G CO., LTD.
    Inventors: Sang-Ku Yoo, Myunggyu Park, In Geun Jo, Taehwan Kwak
  • METHOD FOR CONTROLLING NAD(P)/NAD(P)H RATIO BY OXIDOREDUCTASE
    Publication number: 20140106387
    Abstract: Provided is a method capable of effectively treating various diseases associated with energy excess, such as obesity, diabetes, metabolic syndromes, degenerative diseases and mitochondrial dysfunction-related diseases, via elevation of an NAD(P)+/NAD(P)H ratio by increasing an NAD(P)+ concentration in vivo or in vitro through use of NAD(P)H as a substrate or coenzyme by oxidoreductase such as NAD(P)H:quinone oxidoreductase (NQO1), a method of screening a drug for the same and a therapeutic drug.
    Type: Application
    Filed: December 19, 2013
    Publication date: April 17, 2014
    Applicant: MD BIOALPHA CO., LTD.
    Inventors: Myung-Gyu PARK, Sang-Ku YOO, In Geun JO, Taehwan KWAK
  • PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OR PREVENTION OF DISEASES INVOLVING OBESITY, DIABETES, METABOLIC SYNDROME, NEURO-DEGENERATIVE DISEASES AND MITOCHONDRIA DYSFUNCTION DISEASES
    Publication number: 20130245111
    Abstract: Provided is a pharmaceutical composition for the treatment and prevention of obesity, diabetes, metabolic syndromes, degenerative diseases and mitochondrial dysfunction-related diseases, comprising: a therapeutically effective amount of a compound represented by Formula I below, or a pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, and a pharmaceutically acceptable carrier, a diluent or an excipient, or any combination thereof. wherein R1 through R8 and n are as defined in this disclosure.
    Type: Application
    Filed: April 25, 2013
    Publication date: September 19, 2013
    Applicants: KT & G CO., LTD., MD BIOALPHA CO., LTD.
    Inventors: Sang-Ku YOO, Myunggyu PARK, In Geun JO, Taehwan KWAK
  • Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases
    Patent number: 8466141
    Abstract: Provided is a pharmaceutical composition for the treatment and prevention of obesity, diabetes, metabolic syndromes, degenerative diseases and mitochondrial dysfunction-related diseases, comprising: a therapeutically effective amount of a compound represented by Formula I below, or a pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, and a pharmaceutically acceptable carrier, a diluent or an excipient, or any combination thereof.
    Type: Grant
    Filed: May 22, 2009
    Date of Patent: June 18, 2013
    Assignees: MD Bioalpha Co., Ltd., KT & G Co., Ltd.
    Inventors: Sang-Ku Yoo, Myunggyu Park, In Geun Jo, Taehwan Kwak
  • PHARMACEUTICAL COMPOSITION CONTAINING PHENANTHRENEQUINONE-BASED COMPOUND FOR INTESTINE DELIVERY SYSTEM
    Publication number: 20100234453
    Abstract: Provided is an oral pharmaceutical composition with improved bioavailability and pharmacokinetic properties of a drug, by increasing a bioabsorption rate and an in vivo retention time of an active ingredient via intestine-targeted formulation of a particular phenanthrenequinone-based compound, or a pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, as an active ingredient.
    Type: Application
    Filed: November 26, 2007
    Publication date: September 16, 2010
    Inventors: In Geun Jo, Sang-Ku Yoo, Myung-gyu Park, Taehwan Kwak
  • PHARMACEUTICAL COMPOSITION CONTAINING MICRONIZED PARTICLES OF NAPHTHOQUINONE-BASED COMPOUND
    Publication number: 20100209513
    Abstract: Provided is a pharmaceutical composition having excellent in vivo absorption properties by increasing solubility and absorption rate of a sparingly-soluble naphthoquinone-based compound via incorporation of micronized particles of a certain naphthoquinone-based compound.
    Type: Application
    Filed: October 7, 2008
    Publication date: August 19, 2010
    Inventors: In Geun Jo, Sang-Ku Yoo, Myung-gyu Park, Taehwan Kwak
  • PHARMACEUTICAL COMPOSITION CONTAINING NAPHTHOQUINONE-BASED COMPOUND FOR INTESTINE DELIVERY SYSTEM
    Publication number: 20100062065
    Abstract: Provided is an oral pharmaceutical composition with improved bioavailability and pharmacokinetic properties of a drug, by increasing a bioabsorption rate and an in vivo retention time of an active ingredient via intestine-targeted formulation of a particular naphthoquinone-based compound, or a pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, as an active ingredient.
    Type: Application
    Filed: November 26, 2007
    Publication date: March 11, 2010
    Applicants: MAZENCE INC., KT & G CP., LTD
    Inventors: In Geun Jo, Sang-Ku Yoo, Myung-gyu Park, Taehwan Kwak
  • PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OR PREVENTION OF DISEASES INVOLVING OBESITY, DIABETES, METABOLIC SYNDROME, NEURO-DEGENERATIVE DISEASES AND MITOCHONDRIA DYSFUNCTION DISEASES
    Publication number: 20090292011
    Abstract: Provided is a pharmaceutical composition for the treatment and prevention of obesity, diabetes, metabolic syndromes, degenerative diseases and mitochondrial dysfunction-related diseases, comprising: a therapeutically effective amount of a compound represented by Formula I below, or a pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, and a pharmaceutically acceptable carrier, a diluent or an excipient, or any combination thereof.
    Type: Application
    Filed: May 22, 2009
    Publication date: November 26, 2009
    Applicants: MD BIOALPHA CO., LTD., KT & G CO., LTD.,
    Inventors: Sang-Ku Yoo, Myunggyu Park, In Geun Jo, Taehwan Kwak