Abstract: The present disclosure relates generally to a mucoadhesive nanoparticle delivery system. The nanoparticles are formed from amphiphilic macromolecules conjugated to a mucosal targeting moiety in such a manner that the surface of the nanoparticle is coated with the targeting moiety. The surface density of the targeting moiety can be tuned for adjustable targeting of the nanoparticles to a mucosal site without substantially compromising the stability of the particles. The particles were found to have high loading efficiency and sustained release properties at the mucosal site. The present disclosure also relates to polymers and macromolecules useful in the preparation of the mucoadhesive nanoparticles, as well as compositions, methods, commercial packages, kits and uses related thereto.

Abstract: An AC-driven LED lighting apparatus includes: a triac dimmer to generate a modulated AC voltage by modulating a phase of AC power according to a selected level of dimming; a rectifying circuit to generate drive voltage by full-wave-rectifying the AC voltage having the phase modulated by the triac dimmer; a dimming level detector to detect a dimming level according to the drive voltage; a phase cut reference setting unit for setting a phase cut reference value; and a LED driving module for constant-current-controlling a plurality of LED groups by comparing the detected dimming level with the phase cut reference value, wherein the light emitting element driving module comprises a LED current blocking unit for blocking a drive current supplied to the plurality of LED groups when the dimming level is lower than the phase cut reference value.

Abstract: Antenna package structures are provided to implement wireless communications packages. For example, an antenna package includes multilayer package substrate, a planar antenna array, antenna feed lines, and resistive transmission lines. The planar antenna array includes an array of active antenna elements and dummy antenna elements surrounding the array of active antenna elements. Each active antenna element is coupled to a corresponding one of the antenna feed lines, and each dummy antenna element is coupled to a corresponding one of the resistive transmission lines. Each resistive transmission line extends through the multilayer package substrate and is terminated in a same metallization layer of the multilayer package substrate.

Abstract: A display device includes first and second transparent substrates; a plurality of gate bus lines and data bus lines on the first transparent substrate to define a plurality of pixels; a plurality of color filter layers under the second transparent substrates; and a plurality of microlenses under one of the first and second transparent substrates at positions corresponding to the gate and data bus lines, wherein at least two microlenses among the plurality of microlenses are corresponded to each of the gate or data bus lines in a width direction of each of the gate or data bus lines, and wherein a border between the at least two microlenses is substantially aligned with a center of a corresponding one of the gate and data bus lines, and wherein at least one microlens overlapped with one data bus line does not overlap with the other data bus lines.

Abstract: The disclosed embodiments relate to the design of a high-speed frequency doubler circuit. During operation, the circuit uses a transformer-based balun to convert a single-ended input signal into a differential signal, wherein the transformer-based balun includes a transformer with a primary coil, which receives the single-ended input signal, and a secondary coil, which produces the differential signal. The transformer also includes a central compensation capacitor coupled between a center tap of the secondary coil and ground, wherein the central compensation capacitor acts to suppress common-mode components in the differential signal. Next, the circuit uses a pseudo-differential amplifier to convert the differential signal into a single-ended output signal, which has double the frequency of the single-ended input signal.

Abstract: A liquid storage container comprises: a first lid; a container body having an opening on one end, an interior of the container body and the lid forming a chamber. The opening end of the first lid and the opening end of the container body are rotatably and sealingly connected; and a first pipe and a second pipe communicating the chamber with the outside. The first pipe is provided on the first lid. The second pipe is provided on the container body.

Abstract: The present invention relates to a beta-galactosidase mutant having high transglycosylation activity and containing a C-terminal deletion, and the use thereof and more. More specifically, the present invention relates to a beta-galactosidase mutant having a C-terminal deletion, a gene encoding the same, a recombinant vector containing the gene, a recombinant microorganism transformed with the gene or the recombinant vector, and a method for producing the beta-galactosidase mutant using the recombinant microorganism. Using the high transglycosylation activity of the beta-galactosidase mutant containing the C-terminal deletion according to the present invention, galactooligosaccharide can be efficiently produced in large amounts.

Abstract: A system for integrated cargo inspection includes a non-invasive imaging system scanning a cargo container during an offload operation to obtain a digital image of its contents, a server including a control processor to control components of the system. The components including a computer vision system to perform vision system recognition techniques on the digital image and prepare a report having image icons representing the contents, a machine learning system analytically reviewing the report to generate heuristic analysis used to train the vision system, a computing device displaying at least one of a port plan, a scan view, a results list form dialog, and a results history log graphical displays. A method to implement the system and a non-transitory computer-readable medium are also disclosed.

Abstract: A computer device and a method for reading or writing data by a computer device are provided. In the computer device, a central processing unit (CPU) is connected to a cloud controller using a double data rate (DDR) interface. Because the DDR interface has a high data transmission rate, interruption of CPU can be avoided. In addition, the CPU converts a read or write operation request into a control command and writes the control command into a transmission queue in the cloud controller. Because the cloud controller performs a read operation or a write operation on a network device according to operation information in the control command, after writing the control command into the transmission queue, the CPU does not need to wait for an operation performed by the cloud controller and can continue to perform other processes.

Abstract: The present invention provides a compound of Formula I for use in the treatment, amelioration and/or prevention of diseases and conditions associated with CETP activity, such as atherosclerosis and dyslipidemia, in a subject with high triglyceride level; wherein R1, X1, R7, R5, C, L and p are defined herein. The present invention further provides a combination of pharmacologically active agents for use in the treatment, amelioration and/or prevention of diseases and conditions associated with CETP activity, such as atherosclerosis and dyslipidemia, in a subject with high triglyceride levels.

Abstract: A type of a request that is currently being processed at a system is determined. A distribution is selected from a set of processing time distributions, the distribution forming a model that is applicable to the type. A threshold point is computed for the model. A processing time that exceeds a threshold point processing time is regarded as exhibiting tail latency. Tail latency includes a delay in processing of the request due to a reason other than a utilization of a resource of the system exceeding a threshold utilization and a size of a queue in the system exceeding a threshold size. An evaluation is made that the request will experience tail latency during processing at the system and the processing of the request at the system is aborted. The request is offloaded for processing at a peer system in a load-balanced group of systems.

Abstract: In accordance with an embodiment, described herein is a system and method for semantic analysis and use of song lyrics in a media content environment. Semantic analysis is used to identify persons, events, themes, stories, or other meaningful information within a plurality of songs. For each song, a story graph is generated which describes a narrative within that song's lyrics. The story graph is then used to determine a feature vector associated with the song's narrative. In response to receiving an input vector, for example as a search input for a particular song track, the input vector can be matched against feature vectors of the plurality of songs, to determine appropriate tracks. Example use cases include the selection and delivery of media content in response to input searches for songs of a particular nature, or the recommendation or suggestion of media content in social messaging or other environments.

Abstract: Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (I) are as described herein. A compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (I) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.

Abstract: The present invention relates to a supercritical CO2 power generation system of a series recuperative type. According to an embodiment of the present invention, an inlet temperature of a turbine can be increased to increase a work of the turbine, thereby realizing a cycle design having improved turbine efficiency. Further, the number and diameter of pipes connected to a heat exchanger using an external heat source can be reduced to reduce the plumbing related costs, thereby improving economical efficiency.

Abstract: The present disclosure relates to a method and an apparatus for manufacturing a core-shell catalyst, and more particularly, to a method and an apparatus for manufacturing a core-shell catalyst, in which a particle in the form of a core-shell in which the metal nanoparticle is coated with platinum is manufactured by substituting copper and platinum through a method of manufacturing a metal nanoparticle by emitting a laser beam to a metal ingot, and providing a particular electric potential value, and as a result, it is possible to continuously produce nanoscale uniform core-shell catalysts in large quantities.

Abstract: To provide a reactor to improve evenness in the thickness of shell metals coated on the surface of core particles by increasing area sizes in the reactor chamber to control electric potentials, the present invention is configured to comprise a top surface able to move up and down while serving as a working electrode, a wall serving as a working electrode, a bottom surface, a standard electrode, a power supplying part and a solution injecting part, wherein the top surface can move up and down automatically by an electric motor or manually. Also, the top surface is configured to be suitable for the interior diameter of the reactor chamber, for solutions inside the reactor chamber not to leak from the top surface or from the crevice between the top surface and the wall of the reactor chamber. The bottom surface of the reactor chamber may comprise an impeller or an ultrasonic wave diffuser to bring about even diffusion in the reactor chamber.

Abstract: A sensor for measuring particulate matters is supplied with a bias voltage to form an electric field to increase an accumulated amount of particulate matters at a sensing unit. The sensor includes a sensing unit in which measurement electrodes and ground electrodes are disposed to alternate with one another in a housing fixed to an exhaust pipe. The measurement electrodes are electrically connected to one another, and the ground electrodes are electrically connected to one another. Bias electrodes are disposed between the ground electrodes to supply the bias voltage to the sensing unit. The bias electrodes are electrically connected to one other.

Abstract: The present disclosure provides a method for recognizing an article using a multi-energy spectrum X-ray imaging system and a multi-energy spectrum X-ray imaging system. The method comprises: recognizing an application scenario and/or priori information of the article; selecting a parameter mode suitable for the article from a plurality of parameter modes stored in the multi-energy spectrum X-ray imaging system based on the recognized application scenario and/or priori information; and recognizing the article using the selected parameter mode, wherein the plurality of parameter modes are obtained by optimizing system parameters of the multi-energy spectrum X-ray imaging system under a specific condition using a training sample library for various articles.

Abstract: A detection is made that a first handshake packet has been received from a data processing system at a first system. The first system participates in a load-balanced group managed by a load-balancer. A value is obtained of a metric configured in the first system. from a set of delay functions, a delay function that corresponds to the metric is selected. Using the value of the metric in the selected delay function, a delay period is computed. A transmission of a second handshake packet is delayed for at least the delay period. An intentionally delayed transmission of the second handshake packet is caused after the delay period from the first system to the data processing system.

Abstract: A determination is made at an application executing in conjunction with a switch that a request packet sent to a virtualized computing entity (VCE) connected to the switch should be offloaded to a second VCE. A destination of the request packet is changed from the VCE to the second VCE, to form a first modified request packet. An evaluation is made whether a response packet from the second VCE, which is responsive to the request packet, is usable in the data communication with a sender of the request packet. When the evaluating is affirmative, the first modified request packet is caused to be transmitted from the switch to the second VCE.