Abstract: The present invention relates to an antioxidant cosmetic composition, and more particularly to an antioxidant cosmetic composition containing, as an active ingredient, either an extract of at least one of peony, Polygonati rhizoma and lily, processed using a medicinal herb processing technique, or a mixture of said extract and an extract of at least one of unprocessed peony, Polygonati rhizoma and lily.

Abstract: Disclosed herein is a cosmetic composition containing, as an active ingredient, a mixture of extracts of honey-roasted Adenophora triphylla var. japonica Hara and honey-roasted Angelica tenuissima Nakai, processed using a medicinal herb processing technique, and of extracts of medicinal herbs such as Lycium chinense Mill or Paeonia suffruticosa, and thus shows excellent antioxidant and skin-moisturizing effects.

Abstract: The present invention relates to an antioxidant cosmetic composition, and more particularly to an antioxidant cosmetic composition containing, as an active ingredient, either an extract of at least one of Chrysanthemum indicum and Citrus unshiu peel, processed using a medicinal herb processing technique, or a mixture of said extract and an extract of at least one of unprocessed Chrysanthemum indicum and Citrus unshiu peel.

Abstract: Provided are a lab-on-a-chip and a method of driving the same. The lab-on-a-chip includes a first region where a lower substrate and an upper substrate are bonded to each other, a second region where the lower and upper substrates are not bonded to each other, a gap control member disposed at a terminal of the second region facing an interface between the first and second regions, and configured to control a gap between the lower and upper substrates at the terminal of the second region, and a pressure application member disposed at the terminal of the second region facing the interface between the first and second regions, and configured to apply pressure to the upper substrate at the terminal of the second region to reduce a gap between the lower and upper substrates in the center of the second region. Thus, binding events between a fluid sample to be analyzed and a reagent can be maximized so that a high signal can be obtained using only an infinitesimal quantity of sample.

Abstract: The present invention relates to a cosmetic composition containing a fermented extract of natural material. More specifically, the present invention discloses a cosmetic composition that contains either a salt-fermented extract of at least one of red bean, mung bean and black bean or a salt-fermented extract of a mixture obtained by adding deep-sea water to at least one of red bean, mung bean and black bean, and thus has antioxidant and anti-aging effects.

Abstract: The present invention relates to an extract of a processed herbal medicinal plant and a composition for skin external application which contains the extract. More specifically, the composition for skin external application contains an extract of processed herbal medicinal plant, prepared through a method comprising the steps of: (a) processing an herbal medicinal plant by a process of boiling, steaming, roasting, baking or heating the medicinal plant or a combination of two or more of these processes; (b) obtaining an extract of the processed medicinal plant. The composition shows an improved antioxidant effect.

Abstract: Disclosed herein is a method for preparing ortho-dihydroxyisoflavones using a biotransformation system. More specifically, disclosed is a method for preparing ortho-dihydroxyisoflavones, which comprises biotransforming daidzein or genistein by actinomycete microorganisms, particularly Streptomyces avermitilis, Nocardia farcinica or Streptomyces lincolnesis, in order to efficiently prepare ortho-dihydroxyisoflavones having an excellent antioxidant function and a whitening effect.

Abstract: Disclosed is a combination for skin external use, which contains as an active ingredient an herbal extract complex consisting of Chinese herbal extracts of Granate bark, seed of Prunus armeniaca, Coix lacuma-jobi, Saururus chinensis and Perilla frutescens var. aceta. More particularly, disclosed is a composition for skin external use containing an herbal extract complex, which is prepared by mixing the Chinese herbs with each other at an optimal ratio to prepare an herbal mixture and extracting the herbal mixture to prepare an herbal extract complex, and thus shows the effects of promoting the differentiation of skin keratinocytes, restoring impaired skin barrier function and increasing skin moisturization compared to extracts obtained by extracting each of the herbs alone.

Abstract: The present invention relates to a method for fermenting natural products with salt and fermented extracts prepared thereby. The method comprises: adding a predetermined amount of salt to at least one of natural products, including medicinal herbs and cereals; naturally fermenting the salted material; and extracting the fermented salted material with a solvent. Accordingly, the method can prevent the growth of various bacteria, including putrefactive bacteria, E. coli and anaerobic bacteria, which are harmful to the human body, in the natural product, and it also can prevent the generation of bed smells in the natural product. The fermented extract prepared by the method has fewer side effects and is safer than fermented extracts prepared by conventional fermentation methods.

Abstract: Disclosed herein is a whitening cosmetic composition containing plant-derived ginsenoside Fl (20-O-?-D-glucopyranosyl-20(S)-protopanaxatriol) as an active ingredient. More specifically, the ginsenoside Fl is obtained from particularly a ginseng extract using an acid, a base, an enzyme or microorganism, and a whitening cosmetic composition containing the ginsenoside Fl has an excellent effect of inhibiting melanin biosynthesis, and thus provides an excellent skin whitening effect.

Abstract: Disclosed are an extractor having a “pottery with dark brown glaze” called “Onggi” in Korean, and a method of extracting using the same. The extractor includes a body, a body cover, a heating part, a pottery and a gas valve. The pottery is located within the body. The extractor extracts by injecting nitrogen gas, etc. into the body through a gas valve, thereby rendering the inside of the body to be high pressure state during extraction. Thus, the inside of the body is maintained under high pressure during extraction. Accordingly, an extract is located only within the pottery, and thus changes that can be caused while an extract contacts with the body can be prevented.

Abstract: Provided is a lab-on-a-chip. The lab-on-a-chip includes a first region where a lower substrate and an upper substrate are bonded to each other, a second region where the lower and upper substrates are not bonded, and a gap adjusting member disposed at an end of the second region that is opposite to a boundary between the first and second regions, the gap adjusting member being configured to adjust a gap between the first and second substrates to control a capillary force.

Abstract: Disclosed are aspartic acid salts of 1-cyclopropyl-6-fluoro-7-(8-methoxyimino-2,6-diaza-spiro[3.4]oct-6-yl)-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid, methods for preparing the same, and antimicrobial pharmaceutical compositions comprising the same.

Abstract: Disclosed is a coordination polymer crystal with porous metal-organic frameworks (MOFs), in which, while a crystal state of the coordination polymer crystal is maintained, an additional material selected from the group consisting of an organic compound, a metal cluster, and an organometallic compound is chemically bonded to the coordination polymer crystal. Therefore it is possible easily adsorb and store more guest molecules regardless of a change in an ambient temperature or pressure due to the chemically bonded additional material.

Abstract: Disclosed is a method for the preparation of kaempferol-3-O-rutinoside and a composition of a skin external application comprising kaempferol-3-O-rutinoside as an active ingredient. The method for isolating kaempferol-3-O-rutinoside through hydrolysis uses an enzyme or microbe that removes the sugar selectively from kaempferol-3-O-rutinoside glycosides in a plant extract. Disclosed also is a composition of a skin external application comprising kaempferol-3-O-rutinoside that prevents skin wrinkle.

Abstract: Disclosed are a method for preparing icariside II represented by Formula 1, which inhibits the glycosylation of glycoprotein enzyme tyrosinase by inhibiting the enzymatic activity of alpha-glucosidase, which is an enzyme in the glycosylation of tyrosinase, as well as a skin whitening composition.

Abstract: A method of manufacturing an ultrasonic welding-based microfluidic device, the method including: forming a bottom board having two welding stoppers formed right and left and having a certain height and a certain interval; forming a top board having two energy directors formed with an interval greater than the interval between the two welding stoppers; putting the top board on the bottom board to locate the energy directors at the outside of welding stoppers, respectively; and welding the top board to the bottom board by using ultrasonic welding, wherein a channel is formed between the two welding stoppers without additional energy directors. Accordingly, it is possible to prevent a phenomenon that a fluid irregularly flows due to an uneven surface formed on a side of the channel while the energy directors are melted.

Abstract: There are provided a filter chip in which a filter is mounted on a microfluidic device as a hybrid form, and a method of manufacturing the filter chip. The method includes: forming a bottom structure where a groove for stably mounting a filter is formed; mounting the filter on the groove; forming a top structure forming a fluid inlet for injecting a fluid into the filter; and covering the top structure on a top area of the groove to attach to the bottom structure, wherein the groove and the filter have a shape becoming narrow from the fluid inlet to a fluid outlet in such a way that the fluid receives a rapid change of a capillary force while passing through the filter. Accordingly, blood plasma is capable of being separated at a higher speed by increasing the capillary force of the fluid outlet, thereby obtaining the blood plasma as large amount as possible.

Abstract: A three dimensional microfluidic device is formed by placing a membrane between two micropatterned chips. The membrane is positioned to cover the area where channels intersect. In one embodiment the membrane is porous. The chips are formed of plastic, and are thermally bonded under pressure. Reservoirs are formed on the chips at each end of each channel. The channels are created in the chip by use of an embossing master, such as a patterned silicon wafer. The reservoirs are formed by drilling. A hydraulic press is used to emboss both chips, and is also used to thermally bond the chips and membrane under pressure. The surfaces of the channels are oxidized, changing the surfaces from hydrophobic to hydrophilic.