Abstract: The present invention relates to a composition for administering a double-stranded oligonucleotide structure using an ultrasonic nebulizer. According to the method, the double-stranded oligonucleotide according to the present invention forms self-assembled nanoparticles, which are 90 nm in size and have a neutral charge, and it is possible to deliver the double-stranded oligonucleotide specifically to the nasal cavity and lungs while maintaining not only the same concentration, molecular weight, purity, nanoparticle size, and osmolality as those of the stock material but also the target gene inhibitory activity without cytotoxicity. Thus, the present invention may be useful for the prevention or treatment of respiratory viral infections including COVID-19, pulmonary fibrosis caused by viral infection, or respiratory diseases.

Abstract: A speech recognition method and apparatus for performing speech recognition in response to an activation word determined based on a situation are provided. The speech recognition method and apparatus include an artificial intelligence (AI) system and its application, which simulates functions such as recognition and judgment of a human brain using a machine learning algorithm such as deep learning.

Abstract: A pharmaceutical composition containing a specific related compound within a specified limit and a method for preparing the same are provided.

Abstract: The present invention relates to an Aspergillus niger F22 strain having a nematicidal activity against plant-parasitic nematodes; a nematicidal microorganism agent against plant-parasitic nematodes, containing, as an active ingredient, the strain, a spore, a fungal hyphal mass, or a culture liquid thereof; a method for controlling plant-parasitic nematodes, having a step of administering the microorganism agent to a crop, a crop seed, or a field; and a method for preparation of a nematicidal microorganism agent against plant-parasitic nematodes, having a step of culturing the strain.

Abstract: A speech recognition method and apparatus for performing speech recognition in response to an activation word determined based on a situation are provided. The speech recognition method and apparatus include an artificial intelligence (AI) system and its application, which simulates functions such as recognition and judgment of a human brain using a machine learning algorithm such as deep learning.

Abstract: A speech recognition method and apparatus for performing speech recognition in response to an activation word determined based on a situation are provided. The speech recognition method and apparatus include an artificial intelligence (AI) system and its application, which simulates functions such as recognition and judgment of a human brain using a machine learning algorithm such as deep learning.

Abstract: A pharmaceutical composition containing a specific related compound within a specified limit and a method for preparing the same are provided.

Abstract: A speech recognition method and apparatus for performing speech recognition in response to an activation word determined based on a situation are provided. The speech recognition method and apparatus include an artificial intelligence (AI) system and its application, which simulates functions such as recognition and judgment of a human brain using a machine learning algorithm such as deep learning.

Abstract: The present invention relates to an apparatus for photographing a bedding plane, the apparatus including: a pair of vertical supports; a horizontal support having both ends coupled to the pair of vertical supports, respectively; a main body mounted on the horizontal support so as to be movable in a horizontal direction; a length adjustment unit mounted on the main body so as to be rotatable about the horizontal support, and having a length variable structure for adjusting a length thereof in a direction perpendicular to a longitudinal direction of the horizontal support; a camera mounting jig coupled to the length adjustment unit; a camera mounted on the camera mounting jig; and a level detector mounted on the horizontal support to detect a horizontal state by measuring a degree of inclination of the horizontal support.

Abstract: The present invention relates to an Aspergillus niger F22 strain having a nematicidal activity against plant-parasitic nematodes; a nematicidal microorganism agent against plant-parasitic nematodes, containing, as an active ingredient, the strain, a spore, a fungal hyphal mass, or a culture liquid thereof; a method for controlling plant-parasitic nematodes, having a step of administering the microorganism agent to a crop, a crop seed, or a field; and a method for preparation of a nematicidal microorganism agent against plant-parasitic nematodes, having a step of culturing the strain.

Abstract: The present invention relates to a dengue virus-specific siRNA, a double-stranded oligo RNA structure comprising the siRNA, and a composition for inhibiting dengue virus replication, which comprises the same, in which the double-stranded oligo RNA structure comprises a hydrophilic compound and hydrophobic compound conjugated to both ends of the double-stranded RNA (siRNA) by a single covalent bond or a linker-mediated covalent bond so that they will be efficiently delivered into cells, and can be converted into nanoparticles by hydrophobic interactions between the double-stranded oligo RNA structures in an aqueous solution. The siRNA included in the double-stranded oligo RNA structure acts specifically on all dengue virus serotypes. The present invention also relates to a method for preparing the double-stranded oligo RNA structure, and a pharmaceutical composition for preventing or treating dengue virus infection, which comprises the double-stranded oligo RNA structure.

Abstract: The present invention relates to a macromolecule for delivering protein, polypeptide or peptide drugs and to a production method for the same, as well as to a slow release composition for protein, polypeptide or peptide drugs comprising the same, and more specifically relates to a polylactic acid derivative compound of Chemical formula 1 of which the numerical average molecular weight is no more than 7000 daltons and to a production method for the same, as well as to a slow release composition for protein, polypeptide or peptide drugs using the same and to a production method for the same.

Abstract: A pharmaceutical composition containing a specific related compound within a specified limit and a method for preparing the same are provided.

Abstract: The present invention relates to a dengue virus-specific siRNA, a double-stranded oligo RNA structure comprising the siRNA, and a composition for inhibiting dengue virus replication, which comprises the same, in which the double-stranded oligo RNA structure comprises a hydrophilic compound and hydrophobic compound conjugated to both ends of the double-stranded RNA (siRNA) by a single covalent bond or a linker-mediated covalent bond so that they will be efficiently delivered into cells, and can be converted into nanoparticles by hydrophobic interactions between the double-stranded oligo RNA structures in an aqueous solution. The siRNA included in the double-stranded oligo RNA structure acts specifically on all dengue virus serotypes. The present invention also relates to a method for preparing the double-stranded oligo RNA structure, and a pharmaceutical composition for preventing or treating dengue virus infection, which comprises the double-stranded oligo RNA structure.

Abstract: Provided are embodiments of a section marking apparatus and method for dividing a geological survey site into one or more sections. In some embodiments, the section marking apparatus includes a case part, a fixing shaft part, a section marking part, and a driving pin part. The fixing shaft part is accommodated in the case part. The section marking part is coupled to the fixing shaft part, received in the case part, and has a marker string configured to be extracted to the outside of the case part. The driving pin part is coupled to the fixing shaft part and configured to be driven into a ground surface to secure the section marking apparatus to the ground surface. Accordingly, the section marking apparatus can be used to divide a site when the ground is flat or when the ground is uneven and/or has a slope.

Abstract: The present invention relates to a gene associated with ethanol tolerance, and yeast strains and uses using the same. The yeast strain of this invention may growth under the condition not only with high-concentration ethanol, preferably 6-15% ethanol, but also in high osmotic pressure, preferably 30-40% glucose or sucrose. The present inventors developed yeast strains resistant to high-concentration glucose and ethanol, suggesting that they would be valuably applied to much effective ethanol production, and also be utilized as a superbacteria having tolerance to various stresses for ethanol production with high efficiency.

Abstract: Polylactic acid derivatives capable of forming micelles in an aqueous solution with a pH of 4 or above, having one terminal carboxyl group. The polylactic acid derivatives may be applied as a drug delivery system in various forms since poorly water soluble drugs can be entrapped inside the micelles.

Abstract: An apparatus for measuring geologic strike and dip of a formation. The apparatus includes a support plate, a first rotation plate disposed on the support plate and parallel to the support plate, the first rotation plate being rotatable parallel to the support plate, a second rotation plate hinge-coupled to the first rotation plate, the second rotation plate being rotatable about a hinge shaft, a protractor configured to read an angle between the first rotation plate and the second rotation plate; and a measuring unit including a compass disposed on the second rotation plate.

Abstract: An iron oxyhydroxide includes a plurality of iron oxyhydroxide octahedra components, a plurality of chloride components and at least one of germanium hydroxide components or germanium oxide components. The iron oxyhydroxide octahedra components form a tunnel-type structure. The chloride components are disposed in a tunnel of the tunnel-type structure and bonded to at least one of the iron hydroxide octahedra components. The germanium hydroxide components or the germanium oxide components substitute for at least one of the chloride components.

Abstract: The present invention relates to a chair having an adjustable backrest for spinal protection in that an inside of a backrest structure is provided with an auxiliary backrest for protecting a lumbar vertebrae, and a rack and pinion structure is employed in the backrest and the auxiliary backrest in such a manner that the backrest slides vertically and the auxiliary backrest also slides vertically by the same ratio such that the backrest and the auxiliary backrest can be adjusted appropriately and used flexibly to match the sitting height of the person sitting on the seat, thereby making it possible to provide effective protection to the spinal joints of the waist, back and neck of the user.