Abstract: This invention provides novel indole, indazole, benzimidazole, benzotriazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (SARD) compounds, pharmaceutical compositions and uses thereof in treating hyperproliferations of the prostate including pre-malignancies and benign prostatic hyperplasia, prostate cancer, advanced prostate cancer, castration resistant prostate cancer, other AR-expressing cancers, androgenic alopecia or other hyper androgenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels (through degradation) and/or activity (through inhibition) of any androgen receptor including androgen receptor-full length (AR-FL) including pathogenic and/or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR in a subject.

Abstract: Some embodiments of the present disclosure provide a pneumothorax detection method performed by a computing device. The method may comprise obtaining predicted pneumothorax information, predicted tube information, and a predicted spinal baseline with respect to an input image from a trained pneumothorax prediction model; determining at least one pneumothorax representative position for the predicted pneumothorax information and at least one tube representative position for the predicted tube information, in a prediction image in which the predicted pneumothorax information and the predicted tube information are displayed; dividing the prediction image into a first region and a second region by the predicted spinal baseline; and determining a region in which the at least one pneumothorax representative position and the at least one tube representative position exist among the first region and the second region.

Abstract: A thermoelectric module includes a first electrode, a first oxidation preventing layer, a plurality of first bonding layers containing silver (Ag), a second oxidation preventing layer, a first plating layer, a thermoelectric element, a second plating layer, a third oxidation preventing layer, a second bonding layer containing silver (Ag), a fourth oxidation preventing layer, and a second electrode.

Abstract: The present invention relates to an apparatus and a method for predicting the dispersion of hazardous and noxious substances and, more specifically, provides an apparatus and a method for predicting the dispersion of hazardous and noxious substances, the method: checking the components of the hazardous and noxious substances having leaked into the ocean, so as to classify the hazardous and noxious substances into a corresponding classification set among twelve classification sets by means of at least one of vapor pressure, the degradation in water, or density; dividing the classification sets, in which the hazardous and noxious substances are classified, into one dispersion model among an air dispersion model, a seawater dispersion model, and an air/seawater dispersion model according to the dispersion characteristics thereof; acquiring, from a weather center server, the state information of a sea area, which is set to be different according to the divided dispersion models; and predicting a danger radius for

Abstract: This invention is directed to pyrrole, pyrazole, imidazole, triazole, and morpholine based selective androgen receptor degrader (SARD) compounds including heterocyclic anilide rings and their synthetic precursors. R-isomers, and non-hydroxylated and/or non-chiral propenamides, and pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, triple negative breast cancer, other cancers expressing the androgen receptor, androgenic alopecia or other hyperandrogenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels of androgen receptor-full length (AR-FL) including pathogenic or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR in a subject.

Abstract: A wrist guard includes: a compression part having elasticity and surrounding the periphery of the wrist; a band part disposed on the outer side of the compression part to surround and tighten the circumference of the compression part surrounding the wrist; and a reinforcing bar disposed between the band part and the compression part, located around the ligament covering the wrist tunnel, and extending toward the elbow.

Abstract: A cover window manufacturing system comprises a laser irradiation apparatus including a stage configured to receive a substrate. A first laser module is disposed above the stage to provide a first laser beam to a top surface of the substrate. A controller controls a position of a focal point of the first laser beam on the substrate. An etching apparatus includes a chamber having an etching solution disposed therein. The etching apparatus is configured to receive the substrate processed by the laser irradiation apparatus and etch the substrate processed by the laser irradiation apparatus by immersion in the etching solution.

Abstract: An optical imaging system includes a first lens, a second lens, a third lens, a fourth lens, a fifth lens, a sixth lens, and a seventh lens, sequentially arranged from an object side, wherein TTL/(2*Img HT)<0.7, where a distance on an optical axis from an object-side surface of the first lens to an imaging plane of an image sensor is TTL, and half of a diagonal length of the imaging plane of the image sensor is Img HT, and Fno<1.9, where an F-number of the optical imaging system is Fno.

Abstract: A cover window includes a first member and a second member attached to the first member. A folding portion and a non-folding portion are defined in the cover window, the folding portion includes an inner surface which is compressed when the cover window is folded and an outer surface which is stretched when the cover window is folded, the first member is closer to the inner surface than the second member is, and the second member is closer to the outer surface than the first member is. The second member includes a plurality of support units in the folding portion and spaced apart from each other.

Abstract: An ion source head may include a reaction chamber and a coil. The reaction chamber may be configured to provide an ionization space. The reaction chamber may be divided into a lower region, a central region and an upper region. The coil may be configured to be wound on an outer surface of the reaction chamber. The coil may include a first coil, a second coil and a third coil. The first coil may be spirally wound on an outer surface of the lower region of the reaction chamber. The second coil may be wound on the central region of the reaction chamber. The third coil may be spirally wound on an outer surface of the upper region of the reaction chamber. The second coil may be connected between the first coil and the third coil. The second coil may have a winding direction obliquely to a winding direction of the first and third coils.

Abstract: Structures for a laterally-diffused metal-oxide-semiconductor device and methods of forming a structure for a laterally-diffused metal-oxide-semiconductor device. First and second source/drain regions are formed in a substrate, a gate electrode is formed over the substrate, an interconnect structure over the substrate, and a doped region is arranged in the substrate beneath the first source/drain region. The gate electrode is laterally positioned between the first and second source/drain regions, and the interconnect structure includes a contact connected to the first source/drain region. The doped region has a side edge that is laterally spaced from the contact by a distance.

Abstract: Proposed is a drain trap assembly for sanitary appliances allows a worker to conveniently and swiftly perform assembly for installation and disassembly for maintenance and repair, without use of a separate tool, since a drain trap has a one-touch connection with an inlet pipe and/or an outlet pipe.

Abstract: Disclosed is a seat elevating device including a support unit, a driving unit, and an elevating unit. The support unit is structured such that a first end is coupled to a body of a vehicle and a second end extends upward from the first end and is connected to a first end and a second end of a bar. The driving unit is coupled to an inner side surface of the support unit and equipped with a drive shaft on a side surface thereof. The elevating unit is connected to the drive shaft via a gear unit and is provided with a groove to receive the bar so that the bar slides along the groove. The elevating unit is slidable because it is engaged with the gear unit connected to the drive shaft via a rack gear that extends in parallel with a sliding movement direction of the elevating unit.

Abstract: The present invention provides a lithium ion conductive composite solid electrolyte including an oxide-based crystalline solid electrolyte and a sulfide-based solid electrolyte, wherein the oxide-based solid electrolyte is a garnet-type solid electrolyte represented by a general formula of Li7-3y-zAlyLa3Zr2-zMzO12, wherein M is at least one element selected from the group consisting of niobium (Nb), tantalum (Ta), and tungsten (W), y satisfies 0?y?1, and z satisfies 0?z<2, the sulfide-based solid electrolyte is an argyrodite-based ceramic represented by a general formula of Li7-aPS6-aXa, wherein X is at least one element selected from the group consisting of chlorine (Cl), bromine (Br), and iodine (I), and a satisfies 0?a?2, and the oxide-based solid electrolyte and the sulfide-based solid electrolyte are mixed in a weight ratio of 5.1:4.9 to 8:2.

Abstract: A silicon controlled rectifier is provided. The silicon controlled rectifier comprises a substrate and a first n-well in the substrate. A p+ anode region may be arranged in the first n-well in the substrate. A first p-well may be arranged in the first n-well in the substrate. An n+ cathode region may be arranged in the first p-well in the substrate. A field oxide layer may be arranged over a first portion of the first p-well. A first gate electrode layer may extend over a second portion of the first p-well and over a portion of the field oxide layer.

Abstract: An image display method for preventing display colors from being distorted according to a viewing angle of a driver, and an image display method for a vehicle may include: tracking a sight line of a driver; determining an angle formed between a display and the sight line of the driver; loading a gain value corresponding to the determined angle from a prestored gain compensation table; applying the loaded gain value to image data displayed on the display; and displaying the image data to which the gain value has been applied on the display.

Abstract: A touch device includes: a touch panel including a plurality of X-touch lines and a plurality of Y-touch lines crossing each other; an X-touch driving part simultaneously transmitting at least two of a plurality of X-self signals to the plurality of X-touch lines and sequentially transmitting a plurality of X-mutual signals to the plurality of X-touch lines; and a Y-touch driving part simultaneously transmitting at least two of a plurality of Y-self signals to the plurality of Y-touch lines and transmitting at least two of a plurality of Y-mutual signals to the plurality of Y-touch lines.

Abstract: A manufacturing method of a window includes: radiating a laser to a glass; immersing a laser-irradiated glass in a KOH solution to form a groove in the glass and to perform a primary reinforcement on the glass; masking the groove of a primarily reinforced glass; and performing a secondary reinforcement on a masked glass.

Abstract: An electronic device includes a target address generation circuit configured to generate a counting signal by counting the number of times each logic level combination of an address is input by performing an internal read operation and an internal write operation during an active operation, configured to store the counting signal as the storage counting signal when the counting signal is counted more than a storage counting signal that is stored therein, and configured to store the address, corresponding to the counting signal, as a target address; and a refresh control circuit configured to control a smart refresh operation on the target address.

Abstract: The present invention provides a water-soluble fluorescent compound of resveratrone 6-O-?-glucoside [(E)-4-(8-hydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)naphthalen-2-yl)but-3-en-2-one] and its derivatives of Formula I which have at least one water-soluble substituent, and a method for preparing the same by a photochemical reaction of resveratrol 3-O-?-glucoside and its derivatives of having Formula 3 which are not fluorescent. Said new water-soluble fluorescent compounds has single-photon absorptive characteristics and/or two-photon absorptive characteristics as well as no or little toxicity, and can be usefully utilized in fields that requires water-soluble fluorescent characteristics (diagnosis, fluorescent probe, in vivo imaging, display, etc.).