Abstract: A vehicular heat management system includes a refrigerant circulation line including a compressor, a high pressure side heat exchanger, a heat pump mode expansion valve, an outdoor heat exchanger, and a plurality of low pressure side heat exchangers installed parallel to each other. The refrigerant circulation line further includes a refrigerant pipe having an increased diameter portion formed by increasing the diameter of a specific refrigerant pipe portion among a plurality of refrigerant pipe portions affecting a refrigerant pressure in the refrigerant pipe portions on the intake and discharge sides of the compressor so that the specific refrigerant pipe portion has a larger diameter than other refrigerant pipe portions.

Abstract: The present invention relates to a cosmetic composition for skin whitening.

Abstract: Disclosed are an all-solid-state battery and a method of manufacturing the same, in which the all-solid-state battery includes a coating layer configured such that the surface of a porous network formed by intertwining fibrous carbon is coated with an inorganic electrolyte, thus improving charge/discharge efficiency and lifespan characteristics thereof.

Abstract: Provided is a lubricating oil composition including a lubricating oil additive and a lubricating oil, the lubricating oil additive having nanodiamonds, of which a surface is hydrophobically modified by a surface treatment, dispersed in a base oil. The lubricating oil composition retains dispersibility over a long period of time and thus can ensure storage stability. Machines to which the lubricating oil composition is applied may have improved abrasion resistance as well as improved fuel consumption and reduced noise, and high thermal conductivity of the lubricating oil composition may also increase cooling efficiency and the service life of machines.

Abstract: The present disclosure relates to a high energy density lithium secondary battery having significantly improved high-temperature storage characteristics and lifespan characteristics, which are problematic when a silicon-based negative electrode active material is applied. Specifically, a lithium secondary battery according to an exemplary embodiment includes a positive electrode; a negative electrode facing the positive electrode and including a silicon-based negative electrode active material; and a non-aqueous electrolyte containing a non-aqueous organic solvent including a di-fluoro-based organic solvent and a lithium salt, wherein a content of the di-fluoro-based organic solvent is 5 to 20 vol % with respect to a total volume of the non-aqueous organic solvent.

Abstract: An anode for a secondary battery includes an anode current collector, a first anode active material layer disposed on at least one surface of the anode current collector and including a first anode active material that includes a first silicon composite oxide, and a second anode active material layer disposed on the first anode active material layer and including a second anode active material that includes a second silicon composite oxide. Each of the first silicon composite oxide and the second silicon composite oxide includes a metal. A BET specific surface area of each of the first silicon composite oxide and the second silicon composite oxide is in a range from 2.0 m2/g to 6.5 m2/g.

Abstract: The present invention relates to a WKYMVm peptide analog comprising an amino acid sequence of Trp (W)-Lys (K)-Tyr (Y)-Met (M)-Val (V)-D-Met (m), in which at least one amino acid residue selected from the group consisting of Lys (K), Tyr (Y), and Met (M) in the amino acid sequence is substituted with a ?3-amino acid residue or a peptoid residue, and a use thereof. The WKYMVm peptide analogs of the present invention has effects of increasing stability by increasing in vivo degradation half-life and of promoting activation of innate immune responses by neutrophils through activation of formyl peptide receptors, and thus can be effectively used in preventing or treating a disease that is be prevented or treated by formyl peptide receptors, especially an infectious disease or inflammatory disease.

Abstract: The present invention relates to a double-stranded oligonucleotide which can highly specifically and efficiently inhibit an amphiregulin expression and, preferably, a double-stranded oligonucleotide comprising a sequence in the form of RNA/RNA, DNA/DNA or DNA/RNA hybrid, a double-stranded oligonucleotide structure comprising the double-stranded oligonucleotide, nanoparticles comprising the double-stranded oligonucleotide structure, and a fibrosis or respiratory disease preventive or therapeutic use thereof.

Abstract: Provided is a lubricating oil composition including a lubricating oil additive and a lubricating oil, the lubricating oil additive having nanodiamonds, of which a surface is hydrophobically modified by a surface treatment, dispersed in a base oil. The lubricating oil composition retains dispersibility over a long period of time and thus can ensure storage stability. Machines to which the lubricating oil composition is applied may have improved abrasion resistance as well as improved fuel consumption and reduced noise, and high thermal conductivity of the lubricating oil composition may also increase cooling efficiency and the service life of machines.

Abstract: Provided is a lubricating oil composition including a lubricating oil additive and a lubricating oil, the lubricating oil additive having nanodiamonds, of which a surface is hydrophobically modified by a surface treatment, dispersed in a base oil. The lubricating oil composition retains dispersibility over a long period of time and thus can ensure storage stability. Machines to which the lubricating oil composition is applied may have improved abrasion resistance as well as improved fuel consumption and reduced noise, and high thermal conductivity of the lubricating oil composition may also increase cooling efficiency and the service life of machines.

Abstract: Provided is a lubricating oil composition including a lubricating oil additive and a lubricating oil, the lubricating oil additive having nanodiamonds, of which a surface is hydrophobically modified by a surface treatment, dispersed in a base oil. The lubricating oil composition retains dispersibility over a long period of time and thus can ensure storage stability. Machines to which the lubricating oil composition is applied may have improved abrasion resistance as well as improved fuel consumption and reduced noise, and high thermal conductivity of the lubricating oil composition may also increase cooling efficiency and the service life of machines.

Abstract: The present invention relates to a double-stranded oligonucleotide which can highly specifically and efficiently inhibit an amphiregulin expression and, preferably, a double-stranded oligonucleotide comprising a sequence in the form of RNA/RNA, DNA/DNA or DNA/RNA hybrid, a double-stranded oligonucleotide structure comprising the double-stranded oligonucleotide, nanoparticles comprising the double-stranded oligonucleotide structure, and a fibrosis or respiratory disease preventive or therapeutic use thereof.

Abstract: There is provided a pneumatic tire with a reinforcing part which is mounted on a tire wheel, the pneumatic tire including: a tread having a groove that is formed in a circumferential direction of the tire wheel as being recessed toward a central axis of the tire wheel, a kerf that is formed to intersect the groove as being recessed toward the central axis of the tire wheel, and one or more blocks that are formed between the groove and the kerf and come into contact with a road surface; a shoulder formed at a side of the tread; and a reinforcing part inserted into the groove formed between the one or more blocks. The reinforcing part reduces noise produced due to contact with the road surface by being bent one or more times.

Abstract: Provided is an optical phase shifter. The optical phase shifter includes: a slab waveguide in which a first slab region doped into a first conductivity type and a second slab region doped into a second conductivity type are arranged side by side to form a PN junction; and a rib waveguide disposed on the slab waveguide such that one side of the rib waveguide makes contact with the first slab region, and an opposite side of the rib waveguide makes contact with the second slab region, wherein the rib waveguide includes first to third rib waveguide layers that are sequentially stacked, the first and third rib waveguide layers include silicon (Si), and the second rib waveguide layer includes silicon-germanium (SiGe).

Abstract: The present invention relates to a double-stranded oligonucleotide which can highly specifically and efficiently inhibit an amphiregulin expression and, preferably, a double-stranded oligonucleotide comprising a sequence in the form of RNA/RNA, DNA/DNA or DNA/RNA hybrid, a double-stranded oligonucleotide structure comprising the double-stranded oligonucleotide, nanoparticles comprising the double-stranded oligonucleotide structure, and a fibrosis or respiratory disease preventive or therapeutic use thereof.

Abstract: There is provided a pneumatic tire with a reinforcing part which is mounted on a tire wheel, the pneumatic tire including: a tread having a groove that is formed in a circumferential direction of the tire wheel as being recessed toward a central axis of the tire wheel, a kerf that is formed to intersect the groove as being recessed toward the central axis of the tire wheel, and one or more blocks that are formed between the groove and the kerf and come into contact with a road surface; a shoulder formed at a side of the tread; and a reinforcing part inserted into the groove formed between the one or more blocks. The reinforcing part reduces noise produced due to contact with the road surface by being bent one or more times.

Abstract: Disclosed are a condition based preventive maintenance apparatus and method for a large operation system. The condition based preventive maintenance apparatus for a large operation system comprises: a collection part for collecting sensor data from a plurality of sensors installed in a system; a feature extraction part for wavelet-transforming the collected sensor data and extracting an energy spectrum as a feature value; a calculation part for calculating a slope and an intercept of the extracted feature value; and a monitoring part for monitoring whether the system is broken or not using the calculated slope and intercept.

Abstract: The present invention relates to a double-stranded oligonucleotide which can highly specifically and efficiently inhibit an amphiregulin expression and, preferably, a double-stranded oligonucleotide comprising a sequence in the form of RNA/RNA, DNA/DNA or DNA/RNA hybrid, a double-stranded oligonucleotide structure comprising the double-stranded oligonucleotide, nanoparticles comprising the double-stranded oligonucleotide structure, and a fibrosis or respiratory disease preventive or therapeutic use thereof.

Abstract: A cloud service broker apparatus and method thereof are provided. The cloud service broker apparatus includes a controller configured to provide a brokerage service between a plurality of cloud service providers and a cloud service user by dividing a cloud service requested by the cloud service user into a plurality of cloud service segments and distributing each of the cloud service segments to each of the clouds.

Abstract: An application producing method regarding a first and second application, the method includes receiving an application generation request related to a second application, the second application being subordinate to a first application, generating the second application and computer readable instructions related to a switch interface for selecting at least one of the first and second applications, the switch interface computer readable instructions related to the switch interface, which when executed by at least one application executing apparatus, causes the application executing apparatus to display the switch interface on at least one of the first and second applications, and when the switch interface is in a first state, the first application is controlled based on a first user input received by the at least one application executing apparatus, and when the switch interface is in a second state, the second application is controlled based on the first user input.