Patents by Inventor In-Seok Ko

In-Seok Ko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12187683
    Abstract: Provided are a benzoindazolone compound, or a pharmaceutically acceptable salt, hydrate, solvate, enantiomer, diasteromer, tautomer or prodrug thereof; and an intermediate thereof, wherein the compound is used as a substrate for NQO1 to facilitate a redox reaction of NQO1, and thus is expected to be developable as a medicine for preventing or treating inflammatory diseases.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: January 7, 2025
    Assignee: LMITO THERAPEUTICS INC.
    Inventors: Whee Seong Lee, Eun Ju Lee, In Seok Ko
  • Publication number: 20240034719
    Abstract: Provided are an imidazoquinoline or benzoindazolone compound or a pharmaceutically acceptable salt, hydrate, solvate, enantiomer, diastereomer, tautomer or precursor drug thereof; a use thereof for preventing and treating an inflammatory disease; and an intermediate for preparing same, where the compound is used as a substrate of NQO1 to activate the oxidation-reduction of NQO1, thus making it possible to prevent the expression and activity of inflammatory cytokines, and as such, can be used for preventing or treating diseases associated with NQO1 activity.
    Type: Application
    Filed: August 13, 2021
    Publication date: February 1, 2024
    Applicant: LMITO THERAPEUTICS INC.
    Inventors: Whee Seong LEE, Yong Rae HONG, In Seok KO, Eun Ju LEE
  • Publication number: 20220354825
    Abstract: Provided is a method for the prevention or treatment of inflammatory diseases using a naphthoquinone or benzoindazole compound which increases the ratio of NAD+ and NAD+/NADH through activity in NQO1 in vivo, and through this, activates mitochondria, thereby inducing the metabolism of macrophages towards mitochondrial OXPHOS, which is the major metabolic pathway of M2 phenotype macrophages, such that the macrophages are polarized into an anti-inflammatory macrophage M2 phenotype, and consequently is able to inhibit the expression and activity of inflammatory cytokines, or a pharmaceutically acceptable salt, hydrate, solvate, enantiomer, diasteromer, tautomer, or prodrug thereof.
    Type: Application
    Filed: June 1, 2020
    Publication date: November 10, 2022
    Applicant: LMITO THERAPEUTICS INC.
    Inventors: Whee Seong LEE, Eun Ju LEE, In Seok KO
  • Publication number: 20220144780
    Abstract: Provided are a benzoindazolone compound, or a pharmaceutically acceptable salt, hydrate, solvate, enantiomer, diasteromer, tautomer or prodrug thereof; and an intermediate thereof, wherein the compound is used as a substrate for NQO1 to facilitate a redox reaction of NQO1, and thus is expected to be developable as a medicine for preventing or treating inflammatory diseases.
    Type: Application
    Filed: February 20, 2020
    Publication date: May 12, 2022
    Applicant: LMITO THERAPEUTICS INC.
    Inventors: Whee Seong LEE, Eun Ju LEE, In Seok KO
  • Patent number: 9173275
    Abstract: Provided is an alarm clock integrated with a lamp and a method for controlling an operation of a lamp by the same, and the alarm clock integrated with the lamp further includes a luminance sensor (181) and a sensor connection unit (182), the microcomputer (120) outputs a sensor operation control signal to a sensor connection unit (182) at a lamp operation time set by a lamp operation time setting unit (111), compares a current luminance value input from a luminance sensor (110) and an initial operation luminance value of a lamp (140) stored therein after a luminance sensor (181) is operated, and outputs a pulse control signal to the lamp current adjustment unit (150) so as to change an output of the lamp (140) so that a luminance value of the lamp (140) is changed to a set luminance value when the initial operation luminance value is smaller than the current luminance value.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: October 27, 2015
    Inventors: Jae-Chun Go, In Seok Ko, Hyun Seok Ko
  • Publication number: 20150230318
    Abstract: Provided is an alarm clock integrated with a lamp and a method for controlling an operation of a lamp by the same, and the alarm clock integrated with the lamp further includes a luminance sensor (181) and a sensor connection unit (182), the microcomputer (120) outputs a sensor operation control signal to a sensor connection unit (182) at a lamp operation time set by a lamp operation time setting unit (111), compares a current luminance value input from a luminance sensor (110) and an initial operation luminance value of a lamp (140) stored therein after a luminance sensor (181) is operated, and outputs a pulse control signal to the lamp current adjustment unit (150) so as to change an output of the lamp (140) so that a luminance value of the lamp (140) is changed to a set luminance value when the initial operation luminance value is smaller than the current luminance value.
    Type: Application
    Filed: September 24, 2013
    Publication date: August 13, 2015
    Inventors: Jae-chun GO, In Seok KO, Hyun Seok KO
  • Patent number: 8419380
    Abstract: A noise reducing device for a hermetic type compressor is provided that includes a plurality of cylinders disposed at upper and lower portions thereof, a communication path that provides for communication between inlets of the plurality of cylinders, and a suction pipe coupled to an inlet of one of the plurality of cylinders. Such an arrangement may reduce a number of components and simplify the fabrication process. Accordingly, fabrication costs may be reduced, and vibration due to resonation of a plurality of suction pipes may be avoided. Further, such an arrangement may provide enhanced performance by optimizing a specification of the suction pipe and a suction path thereof.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: April 16, 2013
    Assignee: LG Electronics Inc.
    Inventor: In-Seok Ko
  • Publication number: 20100322796
    Abstract: Disclosed is a hermetic compressor. A plurality of cylinders are disposed at upper and lower sides, a communication path is formed so as to communicate inlets of the cylinders with each other, and a suction pipe connected to a system is coupled to an inlet of one cylinder. This more reduces the number of components and processes than in the conventional case that a plurality of suction pipes are connected to a plurality of cylinders. Accordingly, the fabrication costs can be reduced, and increase of vibration of the hermetic compressor due to resonation of the suction pipes can be prevented. Furthermore, the hermetic compressor can have an enhanced performance by optimizing a specification of the suction pipe and its suction path.
    Type: Application
    Filed: February 25, 2009
    Publication date: December 23, 2010
    Inventor: In-Seok Ko