Abstract: The present disclosure relates to a novel PLK1 degradation inducing compound, a method for preparing the same, and the use thereof. The compounds of the present disclosure exhibit an effect of inducing PLK1 degradation. Therefore, the compounds of the present disclosure may be effectively utilized for preventing or treating PLK1-related diseases.

Abstract: The present invention relates to NLRP3 protein degradation inducing compounds. Specifically, the present invention provides a bifunctional compound in which an NLRP3 protein binding moiety and an E3 ubiquitin ligase binding moiety are connected by a chemical linker, a method for preparing the same, a method for degrading NLRP3 protein using the same, and the use for preventing or treating NLRP3 inflammasome-related diseases.

Abstract: Disclosed is a method for providing sports training videos using a camera and a radar sensor. The present invention is configured so that, when a specific motion of a player is captured by means of radar sensors in a state where a player is being simultaneously captured in real time from various directions by means of one or more cameras during a game or training, only videos of an interval corresponding to the detected specific motion of the player are saved, thus making it possible to: analyze problems that the player has in the game or training through replays of the saved videos; correct problems that the player has during training on the basis of the results of the analysis by distinguishing between the player's incorrect posture and the posture suitable for the player's physical requirements, the player's posture during slumps and during good periods, etc.

Abstract: According to one embodiment of the present disclosure, an electronic device for processing an endoscopic image may comprise a memory configured to store instructions and at least one processor electronically connected to the memory and configured to execute at least a portion of the instructions, wherein the at least one processor obtains an indicator associated with at least one lesion by operating in at least one of a plurality of operation modes.

Abstract: The present invention is related to a mucosal mRNA vaccine. More specifically, the present invention relates to novel mucosal mRNA vaccine based on a peptide-conjugated, mRNA loaded nanoparticle with enhanced vaccine efficacy, and a method of preparing the same.

Abstract: An apparatus for a vehicle may determine one or more abnormalities of battery cells of a battery of a vehicle and may control a normal operation by managing the one or more abnormalities. The battery diagnosis apparatus for the vehicle includes a communication device that provides a communication interface with a plurality of vehicles, and a controller that collects vehicle state information and battery state information from the plurality of vehicles, manages a maximum voltage difference change rate of battery cells for each cumulative mileage with respect to the plurality of vehicles, and diagnoses abnormalities in batteries provided in the plurality of vehicles based on the maximum voltage difference change rate of the battery cells for each cumulative mileage.

Abstract: A composition for treating an infection or disease caused by a pathogenic Escherichia coli includes a Myoviridae bacteriophage Esc-COP-23 having an ability to lyse the pathogenic Escherichia coli and a pharmaceutically acceptable carrier. A method for treating an infection or disease caused by a pathogenic Escherichia coli includes administering to a subject a Myoviridae bacteriophage and lysing the pathogenic Escherichia coli by the Myoviridae bacteriophage.

Abstract: The present invention relates to a Siphoviridae bacteriophage STP-2 (Accession number: KCTC 12853BP) isolated from nature and characterized by having the ability to destroy Salmonella Typhimurium and having a genome represented by SEQ ID NO:1; and to a method for preventing and treating diseases caused by Salmonella Typhimurium using Siphoviridae bacteriophage STP-2 containing the same as an active ingredient.

Abstract: There is provided a method and an apparatus capable of generating contrast-enhanced medical images that clearly show contrast-enhanced areas from non-contrast medical images of cross-sections of a patient's body provided by a medical imaging apparatus such as a CT scanner using a neural network model.

Abstract: The present invention relates to an anticancer composition containing as an active ingredient a compound inducing cell senescence and apoptosis. The compound of the present invention can discriminate cancer cells and normal cells and induce both cell senescence and apoptosis in a cancer cell-specific manner. Thus, the compound does not need the attachment of any cancer cell-specific targeting substance thereto, can minimize the frequent adverse effects caused by the attack of anticancer agents on normal cells, and exhibits a potent anticancer effect on the basis of the aforementioned dual action.

Abstract: A knife storage device includes a storage main body in which a knife having a blade and a handle is stored, wherein the storage main body has a blade accommodation part in which the blade is accommodated and a handle loading part in which the handle is loaded, and the handle is loaded in the handle loading part so that the knife is stably stored.

Abstract: Provided are a binder for an electrode, a negative electrode for a secondary battery including the binder, and a secondary battery, in which an active material layer is prevented from lifting from a negative electrode base material. A binder forming an electrode of a secondary battery includes a binder particle and a temperature-sensitive polymer grafted on a surface of the binder particle.

Abstract: A composition for preventing or treating an infection or disease caused by enterotoxigenic Bacteroides fragilis includes a Siphoviridae bacteriophage (Bac-FRP-4) having an ability to lyse the enterotoxigenic Bacteroides fragilis cells and a pharmaceutically acceptable carrier. A method for preventing or treating an infection or disease caused by enterotoxigenic Bacteroides fragilis includes administering to a subject a Siphoviridae bacteriophage and lysing the enterotoxigenic Bacteroides fragilis cells by the Siphoviridae bacteriophage.

Abstract: A composition for preventing or treating an infection or disease caused by enterotoxigenic Bacteroides fragilis includes a Siphoviridae bacteriophage (Bac-FRP-5) having an ability to lyse the enterotoxigenic Bacteroides fragilis cells and a pharmaceutically acceptable carrier. A method for preventing or treating an infection or disease caused by enterotoxigenic Bacteroides fragilis includes administering to a subject a Siphoviridae bacteriophage and lysing the enterotoxigenic Bacteroides fragilis cells by the Siphoviridae bacteriophage.

Abstract: A composition for preventing or treating an infection or disease caused by enterotoxigenic Bacteroides fragilis includes a Siphoviridae bacteriophage (Bac-FRP-3) having an ability to lyse the enterotoxigenic Bacteroides fragilis cells and a pharmaceutically acceptable carrier. A method for preventing or treating an infection or disease caused by enterotoxigenic Bacteroides fragilis includes administering to a subject a Siphoviridae bacteriophage and lysing the enterotoxigenic Bacteroides fragilis cells by the Siphoviridae bacteriophage.

Abstract: The present invention relates to a Myoviridae bacteriophage Aer-HYP-3 (Accession number: KCTC 13479BP) isolated from nature, which has the ability to kill Aeromonas hydrophila bacteria and has the genome represented by SEQ ID NO: 1, and to a method of preventing and treating a disease caused by Aeromonas hydrophila bacteria using a composition containing the same as an active ingredient.

Abstract: A method for preparing a porcine myoglobin includes: constructing a first plasmid containing genes for heme biosynthesis pathway enzymes; constructing a second plasmid containing a gene for Sus scrofa myoglobin MYG; constructing a first Escherichia coli production host containing the first plasmid and the second plasmid; and producing the porcine myoglobin by culturing the first Escherichia coli production host. A composition useful as a meat flavor and/or an iron supplement includes the porcine myoglobin prepared in accordance with the method.

Abstract: Disclosed are an apparatus and method for diagnosing a battery of a vehicle. The apparatus includes storage that stores a threshold value for each accumulated driving distance section corresponding to a state of the vehicle, and a controller that collects vehicle state information and battery state information from a plurality of vehicles, determines a maximum voltage difference change rate of a battery cell for an accumulated driving distance for each vehicle, and diagnoses an abnormality in a battery provided in each vehicle based on the maximum voltage difference change rate of the battery cell for the accumulated driving distance of each vehicle and a threshold value corresponding to the maximum voltage difference change rate.

Abstract: Disclosed are a battery diagnosis apparatus for a vehicle and a method thereof. The battery diagnosis apparatus for the vehicle includes a communication device that provides a communication interface with a plurality of vehicles, and a controller that collects vehicle state information and battery state information from the plurality of vehicles, manages a maximum voltage difference change rate of battery cells for each cumulative mileage with respect to the plurality of vehicles, and diagnoses abnormalities in batteries provided in the plurality of vehicles based on the maximum voltage difference change rate of the battery cells for each cumulative mileage.