Patents by Inventor In-sook Yi
In-sook Yi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220177552Abstract: The present invention relates to a binding molecule having neutralizing activity against Middle East Respiratory Syndrome-Coronavirus (MERS-CoV). More particularly, the present invention relates to a binding molecule having strong ability to bind to an S protein of MERS-CoV and neutralizing activity against MERS-CoV and thus being very useful in the prevention, treatment or diagnosis of MERS-CoV infection.Type: ApplicationFiled: November 30, 2018Publication date: June 9, 2022Applicant: CELLTRION INC.Inventors: Soo Young Lee, Kye Sook Yi, Cheol Min Kim, Kyung Min Song, Yeon Jin Bae, Woo Joo Kim, Hee Jin Cheong, Joon Young Song, Man Seong Park, Ji Yun Noh
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Patent number: 10703802Abstract: The present invention provides a composition comprising at least two influenza A virus-neutralizing binding molecules that bind to an epitope in the stem region of influenza A virus hemagglutinin (HA) protein, the method comprising: i) a first binding molecule capable of neutralizing at least one influenza A virus subtype selected from the group consisting of H1, H2, H5 and H9; ii) a second binding molecule capable of neutralizing at least one influenza A virus subtype selected from the group consisting of H1, H3, H5, H7 and H9. The mixed composition of the present invention can effectively neutralize the multiple influenza subtypes of both phylogenetic group 1 and phylogenetic group 2 and can be used in combination with a chemical compound. Thus, the composition of the present invention is very useful for the prevention and treatment of a disease by influenza virus.Type: GrantFiled: March 28, 2014Date of Patent: July 7, 2020Assignee: CELLTRION, INC.Inventors: Seung Suh Hong, Shin Jae Chang, Ki Sung Kwon, Kye Sook Yi, Sung Hwan Kim, Eun Beom Lee, Jae Won Lee, So Jung Lee, Ji Young Shin, Myung Sam Cho
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Patent number: 10507240Abstract: The present invention relates to an epitope specific to hepatitis B virus surface antigen and a binding molecule binding to the same for neutralizing hepatitis B virus. Since the epitope provided by the present invention is produced by forming a three-dimensional structure and does not comprise a determinant, by which escape mutation is induced against an administration of existing vaccines or HBIg, a composition comprising an antibody biding to the epitope or a vaccine composition comprising the epitope has a very low possibility of causing a decrease in efficacy due to escape mutation. Therefore, such an antibody or vaccine composition can be very effectively used in prevention and/or treatment of HBV.Type: GrantFiled: November 27, 2015Date of Patent: December 17, 2019Assignee: CELLTRION, Inc.Inventors: Joon Sun Yoon, Hwa Jin Lee, Kye Sook Yi, Cheol Min Kim, Byung Pil Lim, Shin Jae Chang, Seung Suh Hong
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Patent number: 9856312Abstract: The present invention relates to a binding molecule having influenza A virus-neutralizing activity derived from a human B cell, and the binding molecule having the influenza A virus-neutralizing activity, according to the present invention, is a binding molecule that is derived from a B cell that is selected from the blood of a patient infected with an influenza A virus, and has neutralizing activity against influenza A viruses, and thus is useful in preventing and treating disease derived from the influenza A virus, and can be useful in diagnosing the influenza A virus by using the binding molecule according to the present invention.Type: GrantFiled: September 8, 2016Date of Patent: January 2, 2018Assignee: Celltrion Inc.Inventors: Shin Jae Chang, Ki Sung Kwon, Kye Sook Yi, Hyun Joo Lee, Jae Won Jeon, Hwang Keun Jun, Min Seok Chang
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Patent number: 9834594Abstract: The present invention relates to human monoclonal antibodies derived from human B cells present in the blood of patients who had recovered from infection with influenza A viruses, wherein the monoclonal antibodies have neutralizing activity against influenza A viruses. The anti-influenza A virus monoclonal antibody of the present invention has binding and neutralizing activities against at least one influenza A virus selected from the group consisting of influenza A virus H1, H2 and H5 subtypes, and thus it is useful for the prevention and treatment of a disease caused by the influenza A virus and is also useful for diagnosis of influenza A virus infection.Type: GrantFiled: January 6, 2017Date of Patent: December 5, 2017Assignee: CELLTRION, INC.Inventors: Shin Jae Chang, Jong Mook Kim, Kye Sook Yi, Hyun Joo Lee
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Patent number: 9831487Abstract: Provided herein is a method for forming a transparent electrode film, the method comprising forming an electrode pattern by printing an electrode pattern on a release film using a metal ink composition; forming an insulating layer by applying a curable resin on the release film on which the electrode pattern has been formed; forming a substrate layer by laminating a substrate on the insulating layer; removing the release film; and forming a conductive layer by applying a conductive material on the electrode pattern from which the release film has been removed.Type: GrantFiled: May 16, 2014Date of Patent: November 28, 2017Assignee: INKTEC CO., LTD.Inventors: Kwang-Choon Chung, In-Sook Yi, Ji Hoon Yoo, Joonki Seong, Dae Sang Han
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Publication number: 20170326231Abstract: The present invention relates to an epitope specific to hepatitis B virus surface antigen and a binding molecule binding to the same for neutralizing hepatitis B virus. Since the epitope provided by the present invention is produced by forming a three-dimensional structure and does not comprise a determinant, by which escape mutation is induced against an administration of existing vaccines or HBIg, a composition comprising an antibody biding to the epitope or a vaccine composition comprising the epitope has a very low possibility of causing a decrease in efficacy due to escape mutation. Therefore, such an antibody or vaccine composition can be very effectively used in prevention and/or treatment of HBV.Type: ApplicationFiled: November 27, 2015Publication date: November 16, 2017Applicant: CELLTRION, INC.Inventors: Joon Sun Yoon, Hwa Jin Lee, Kye Sook Yi, Cheol Min Kim, Byung Pil Lim, Shin Jae Chang, Seung Suh Hong
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Publication number: 20170158754Abstract: The present invention relates to human monoclonal antibodies derived from human B cells present in the blood of patients who had recovered from infection with influenza A viruses, wherein the monoclonal antibodies have neutralizing activity against influenza A viruses. The anti-influenza A virus monoclonal antibody of the present invention has binding and neutralizing activities against at least one influenza A virus selected from the group consisting of influenza A virus H1, H2 and H5 subtypes, and thus it is useful for the prevention and treatment of a disease caused by the influenza A virus and is also useful for diagnosis of influenza A virus infection.Type: ApplicationFiled: January 6, 2017Publication date: June 8, 2017Inventors: Shin Jae Chang, Jong Mook Kim, Kye Sook Yi, Hyun Joo Lee
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Patent number: 9573991Abstract: The present invention relates to human monoclonal antibodies derived from human B cells present in the blood of patients who had recovered from infection with influenza A viruses, wherein the monoclonal antibodies have neutralizing activity against influenza A viruses. The anti-influenza A virus monoclonal antibody of the present invention has binding and neutralizing activities against at least one influenza A virus selected from the group consisting of influenza A virus H1, H2 and H5 subtypes, and thus it is useful for the prevention and treatment of a disease caused by the influenza A virus and is also useful for diagnosis of influenza A virus infection.Type: GrantFiled: March 7, 2011Date of Patent: February 21, 2017Assignee: CELLTRION, INC.Inventors: Shin Jae Chang, Jong Mook Kim, Kye Sook Yi, Hyun Joo Lee
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Publication number: 20170037113Abstract: The present invention relates to a binding molecule having influenza A virus-neutralizing activity derived from a human B cell, and the binding molecule having the influenza A virus-neutralizing activity, according to the present invention, is a binding molecule that is derived from a B cell that is selected from the blood of a patient infected with an influenza A virus, and has neutralizing activity against influenza A viruses, and thus is useful in preventing and treating disease derived from the influenza A virus, and can be useful in diagnosing the influenza A virus by using the binding molecule according to the present invention.Type: ApplicationFiled: September 8, 2016Publication date: February 9, 2017Inventors: Shin Jae Chang, Ki Sung Kwon, Kye Sook Yi, Hyun Joo Lee, Jae Won Jeon, Hwang Keun Jun, Min Seok Chang
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Patent number: 9524046Abstract: Provided herein is a method for producing a hybrid transparent electrode, the method including filling grooves of a substrate with a conductive metal ink composition; filling the grooves with residue conductive metal ink composition that remains on a surface of the substrate as the grooves are being filled with the conductive metal ink composition to form an electrode pattern; and forming a conductive layer including a conductive material on the electrode pattern.Type: GrantFiled: May 16, 2014Date of Patent: December 20, 2016Assignee: INKTEC CO., LTD.Inventors: Kwang-Choon Chung, In-Sook Yi, Ji Hoon Yoo, Joonki Seong, Dae sang Han
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Patent number: 9475861Abstract: The present invention relates to a binding molecule having influenza A virus-neutralizing activity derived from a human B cell, and the binding molecule having the influenza A virus-neutralizing activity, according to the present invention, is a binding molecule that is derived from a B cell that is selected from the blood of a patient infected with an influenza A virus, and has neutralizing activity against influenza A viruses, and thus is useful in preventing and treating disease derived from the influenza A virus, and can be useful in diagnosing the influenza A virus by using the binding molecule according to the present invention.Type: GrantFiled: September 27, 2012Date of Patent: October 25, 2016Assignee: Celltrion Inc.Inventors: Shin Jae Chang, Ki Sung Kwon, Kye Sook Yi, Hyun Joo Lee, Jae Won Jeon, Hwang Keun Jun, Min Seok Chang
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Publication number: 20160181592Abstract: Provided herein is a method for forming a transparent electrode film, the method comprising forming an electrode pattern by printing an electrode pattern on a release film using a metal ink composition; forming an insulating layer by applying a curable resin on the release film on which the electrode pattern has been formed; forming a substrate layer by laminating a substrate on the insulating layer; removing the release film; and forming a conductive layer by applying a conductive material on the electrode pattern from which the release film has been removed.Type: ApplicationFiled: May 16, 2014Publication date: June 23, 2016Inventors: Kwang-Choon Chung, In-Sook Yi, Ji Hoon Yoo, Joonki Seong, Dae Sang Han
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Publication number: 20160132141Abstract: Provided herein is a method for producing a hybrid transparent electrode, the method including filling grooves of a substrate with a conductive metal ink composition; filling the grooves with residue conductive metal ink composition that remains on a surface of the substrate as the grooves are being filled with the conductive metal ink composition to form an electrode pattern; and forming a conductive layer including a conductive material on the electrode pattern.Type: ApplicationFiled: May 16, 2014Publication date: May 12, 2016Inventors: Kwang-Choon CHUNG, In-Sook YI, Ji Hoon YOO, Joonki SEONG, Dae sang HAN
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Publication number: 20160052997Abstract: The present invention provides a composition comprising at least two influenza A virus-neutralizing binding molecules that bind to an epitope in the stem region of influenza A virus hemagglutinin (HA) protein, the method comprising: i) a first binding molecule capable of neutralizing at least one influenza A virus subtype selected from the group consisting of H1, H2, H5 and H9; ii) a second binding molecule capable of neutralizing at least one influenza A virus subtype selected from the group consisting of H1, H3, H5, H7 and H9. The mixed composition of the present invention can effectively neutralize the multiple influenza subtypes of both phylogenetic group 1 and phylogenetic group 2 and can be used in combination with a chemical compound. Thus, the composition of the present invention is very useful for the prevention and treatment of a disease by influenza virus.Type: ApplicationFiled: March 28, 2014Publication date: February 25, 2016Inventors: Seung Suh HONG, Shin Jae CHANG, Ki Sung KWON, Kye Sook YI, Sung Hwan KIM, Eun Beom LEE, Jae Won LEE, So Jung LEE, Ji Young SHIN, Myung Sam CHO
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Publication number: 20140234336Abstract: The present invention relates to a binding molecule having influenza A virus-neutralizing activity derived from a human B cell, and the binding molecule having the influenza A virus-neutralizing activity, according to the present invention, is a binding molecule that is derived from a B cell that is selected from the blood of a patient infected with an influenza A virus, and has neutralizing activity against influenza A viruses, and thus is useful in preventing and treating disease derived from the influenza A virus, and can be useful in diagnosing the influenza A virus by using the binding molecule according to the present invention.Type: ApplicationFiled: September 27, 2012Publication date: August 21, 2014Inventors: Shin Jae Chang, Ki Sung Kwon, Kye Sook Yi, Hyun Joo Lee, Jae Won Jeon, Hwang Keun Jun, Min Seok Chang
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Publication number: 20130004505Abstract: The present invention relates to human monoclonal antibodies derived from human B cells present in the blood of patients who had recovered from infection with influenza A viruses, wherein the monoclonal antibodies have neutralizing activity against influenza A viruses. The anti-influenza A virus monoclonal antibody of the present invention has binding and neutralizing activities against at least one influenza A virus selected from the group consisting of influenza A virus H1, H2 and H5 subtypes, and thus it is useful for the prevention and treatment of a disease caused by the influenza A virus and is also useful for diagnosis of influenza A virus infection.Type: ApplicationFiled: March 7, 2011Publication date: January 3, 2013Applicant: CELLTRION, INC.Inventors: Shin Jae Chang, Jong Mook Kim, Kye Sook Yi, Hyun Joo Lee
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Publication number: 20030136513Abstract: There is provided a semiconductor manufacturing apparatus comprising: a cassette station 16 in which wafers 18 are loaded; a stand-by conveying robot 10 for taking the wafers 18 out of the cassette station 16; a load lock chamber 12 in which the wafers 18 taken by the stand-by conveying robot 10 are accommodated; and a reaction chamber 14 placed in contact with the load lock chamber 12, the reaction chamber 14 having a shuttle blade 20 for drawing the wafers accommodated in the load lock chamber out of the load lock chamber 12 in a vacuum state and loading etched wafers in the load lock chamber, a rotary robot 26 for rotatively transferring the wafers taken out of the load lock chamber to be placed on the shuttle blade 20, and a heater stage 24 for etching the wafers transferred by the rotary robot 26 using a plasma generator 28, in which a pre-heating part 22 is placed above the shuttle blade 20, for pre-heating the wafers transferred into the reaction chamber 14 from the load lock chamber 12 before they areType: ApplicationFiled: January 22, 2002Publication date: July 24, 2003Inventors: Soon Ho Lee, Seong Sook Yi, Jin Seok Park, Sung Up Yoon, Jong Sik Kim, Byung Chul Kim, Byung Deok Yoo
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Ferroelectric memory having dielectric layer of siof and method for fabricating the dielectric layer
Publication number: 20020022277Abstract: A ferroelectric memory having a dielectric layer comprised of SiOF, and a method for fabricating the SiOF dielectric layer are provided. Degradation in the ferroelectric properties due to hydrogen atoms can be prevented by depositing a SiOF dielectric layer using SiF4, instead of depositing a SiO2 dielectric layer, which has been conventionally used. The ferroelectric memory device, and the method of making the device, provide a stabilized device having less or no degradation in the ferroelectric properties.Type: ApplicationFiled: May 12, 2000Publication date: February 21, 2002Inventors: Young-soo Park, In-sook Yi -
Patent number: 5084289Abstract: A method for inhibiting the oxidation of edible oils and fats by forming a reverse micelle by admixing a mixture of an aqueous solution containing a water-soluble antioxidant with a surfactant and said oils or fats.Type: GrantFiled: January 18, 1990Date of Patent: January 28, 1992Assignee: Korea Food Research InstituteInventors: Hyun-Kyung Shin, Dae-Seok Han, Ock-Sook Yi