Abstract: The present invention concerns a method for producing a microscopic image with an extended depth of field by means of a microscope. The microscope comprises an images sensor that comprises pixels that are arranged as a matrix that is formed by lines. In a step of the method, a plurality of microscopic frames of a specimen is acquired while a focus position (z) is changed. The microscopic frames are acquired line by line. The focus position (z) is changed over a course of acquiring individuals of the microscopic frames. In a further step, parts of individuals of the acquired lines are identified. These parts sharply image the specimen. The identified parts of the lines are composed in order to form a microscopic image of the specimen with an extended depth of field. Furthermore, the present invention concerns a microscope.

Abstract: The present disclosure provides a method and apparatus for biomolecular multiplexed imaging through the iterative unmixing of fluorophores. According to the first embodiments of the present disclosure, although signals of two fluorophores are detected in the first fluorescent detection spectral range, the signals of the two images obtained from two detection spectral ranges can be unmixed through the iterative minimization of mutual information. Furthermore, the present disclosure provides a multi-color unmixing method and apparatus through the iterative minimization of mutual information. In the second embodiments of the present disclosure, a plurality of images of a plurality of fluorophores marking different biomolecules, respectively, for example, N fluorophores are obtained. Images, each containing the signals of single fluorophore can be obtained from the obtained images while minimizing the mutual information shared by images of each of pairs each consisting of two of the obtained images.

Abstract: Provided is a method of operating a terminal. The method includes determining a profile item applicable to the profile view for the account based on an input received by the terminal and a coordinate indicating a position where the profile item is provided on the profile view. The method includes displaying the profile item on a screen of the terminal based on the determined profile item and the determined coordinate. The method includes receiving an input related to the profile item, and displaying a visual effect corresponding to the input on the screen.

Abstract: Disclosed herein are a microorganism with excellent deacetoxycephalosporin C (DAOC) productivity and a use thereof. A mutant microorganism with improved DAOC productivity and a use thereof for producing 7-aminodeacetoxycephalosporanic acid (7-ADCA) are provided.

Abstract: A non-line-of-sight radar apparatus includes a first radar receiver to convert a first frequency radar signal received through a non-line-of-sight into a digital signal and to output a first path signal; a first signal processor to receive a second path signal from a direct-line-of-sight detection apparatus detecting a direct-line-of-sight, to cancel a direct-line-of-sight signal irrelevant to the non-line-of-sight included in the first path signal using the second path signal, and to extract a non-line-of-sight signal; and a first signal detector to detect an object on a non-line-of-sight based on the non-line-of-sight signal.

Abstract: An esophageal deflection device includes an elongate outer tube that has a natural curved deflection at a position that corresponds to a targeted esophagus region for deflection. The outer diameter of the outer tube is substantially matched to an inner diameter of the esophagus to closely contact the esophagus wall, or is at least half of the inner diameter, or is smaller and includes suction ports for drawing the esophagus wall inward. An insertion rod or tube includes a portion that is stiffer than the curved deflection, and slides into the elongate outer tube to straighten the tube and can serve to guide the deflection device into an esophagus. Subsequent withdrawal of the insertion tube or rod will allow the curved deflection to return to its natural shape and deflect the targeted region of the esophagus.

Abstract: Disclosed are an oral solid dosage form composition comprising an active ingredient and a solubilizing carrier wherein a foaming ingredient is used to improve disintegration, dispersion or dissolution, and a preparation method therefor.

Abstract: Disclosed are an apparatus for configuring an equipment behavior catalog (EBC) and a virtual production system using an EBC. The apparatus for configuring the EBC according to an aspect of the present invention includes an artificial intelligence model storage configured to store an artificial intelligence model, and an EBC storage configured to store an EBC including artificial intelligence model data for the artificial intelligence model stored in the artificial intelligence model storage.

Abstract: Provided is an optical system which may acquire a hyperspectral image by acquiring a spectral image of an object to be measured, which includes, to collect spectral data and train the neural network, an image forming part forming an image from an object to be measured and transmitting collimated light, a slit moving to scan the incident image and passing and outputting a part of the formed image, and a first optical part obtaining spectral data by splitting light of the image received through the slit by wavelength. Also, the system includes, to decompose overlapped spectral data and to infer hyperspectral image data through the trained neural network, an image forming part forming an image from an object to be measured and transmitting collimated light, and a first optical part obtaining spectral data by splitting light of the received image by wavelength.

Abstract: A battery inspection apparatus capable of self-diagnosing failure is provided. The battery inspection apparatus includes a contact probe, a power supply module, a power cable for providing a path for supplying the power generated by the power supply module to the contact probe, a voltage measuring module, a measuring cable configured to measure a voltage of the contact probe by the voltage measuring module, a switching module configured to selectively connect the voltage measuring module to the power cable or the measuring cable, and a control module configured to determine whether at least one of the contact probe or the power cable is abnormal based on the voltage measurement value of the voltage measuring module according to a connection state of the switching module. A verification device capable of diagnosing failure of the battery inspection apparatus is also provided.

Abstract: A display device is disclosed that includes a pixel component configured to output an image based on a first driving frequency, a scan driver configured to sequentially provide a scan signal to each pixel row in each frame based on the first driving frequency, and a driving controller configured control the scan driver such that, in the case where image data includes data corresponding to a static image, a display area is divided into a first area for the static image, and a second area for a video, and the first area is driven at a second driving frequency, and the second area is driven at a third driving frequency. The driving controller may control the scan driver such that a driving frequency corresponding to the first area is reduced to the second driving frequency, and a driving frequency corresponding to the second area is increased to the third driving frequency.

Abstract: The present disclosure relates to a novel anti-HER2 antibody or an antigen-binding fragment thereof used in the prevention or treatment of cancer, a chimeric antigen receptor including the same, and uses thereof. The antibody of the present disclosure is an antibody that specifically binds to HER2 which is highly expressed in cancer cells (particularly, breast cancer or gastric cancer cells), and binds to an epitope that is different from an epitope to which trastuzumab binds.

Abstract: The present invention relates to a composition for preventing or treating transplantation rejection or a transplantation rejection disease, comprising a novel compound and a calcineurin inhibitor. A co-administration of the present invention 1) reduces the activity of pathogenic Th1 cells or Th17 cells, 2) increases the activity of Treg cells, 3) has an inhibitory effect against side effects, such as tissue damage, occurring in the sole administration thereof, 4) inhibits various pathogenic pathways, 5) inhibits the cell death of inflammatory cells, and 6) increases the activity of mitochondria, in an in vivo or in vitro allogenic model, a transplantation rejection disease model, a skin transplantation model, and a liver-transplanted patient, and thus inhibits transplantation rejection along with mitigating side effects possibly occurring in the administration of a conventional immunosuppressant alone.

Abstract: An optical imaging system includes a first lens, a second lens, a third lens, a fourth lens, a fifth lens, a sixth lens, and a seventh lens sequentially disposed in numerical order along an optical axis of the optical imaging system from an object side of the optical imaging system toward an imaging plane of the optical imaging system, wherein the optical imaging system satisfies 0.5<L12345TRavg/L7TR<0.9, where L12345TRavg is an average value of overall outer diameters of the first to fifth lenses, L7TR is an overall outer diameter of the seventh lens, and L12345TRavg and L7TR are expressed in a same unit of measurement.

Abstract: A fingerprint ridge digital enhancement apparatus includes: a fingerprint image obtainer configured to obtain a fingerprint image; a pixel value extractor configured to divide an area with ridges and an area without ridges in the fingerprint image, and to extract a pixel value according to a color model for each area; an outlier detector configured to detect an outlier of the pixel value according to the color model for each area; a correction operator configured to calculate the average and standard deviation of pixel values according to the color model for each area from which the outlier is removed; a parameter operator configured to set a parameter that is a criterion for dividing each area, and to operate a reference value of the parameter; and a matrix operator configured to generate and operate a matrix including the pixel value according to the color model of the fingerprint image and the reference value of the parameter.

Abstract: Disclosed is an automatic switching communication method including: obtaining LTE communication state information of a main communication module for communicating with outside through a directional antenna and a sub-communication module for communicating with the outside through a directional antenna; registering the LTE communication state information of the main communication module and the sub-communication module in a routing table; determining whether the main communication module and the sub-communication module are capable of performing LTE communication; and comparing with pre-specified communication quality coefficients of the main communication module and the sub-communication module to adjust a routing path.

Abstract: Provided is a method of improving skin condition by applying to the skin of a subject a cosmetic composition comprising black yeast-derived exosomes as an active ingredient and thereby improving the skin condition, particularly skin elasticity improvement, skin wrinkle reduction, skin texture improvement, skin tone improvement, skin brightness improvement, skin regeneration, skin moisturization, and/or whitening.

Abstract: A high-voltage battery control apparatus includes a plurality of high-voltage battery controllers configured to respectively monitor states of a plurality of high-voltage batteries included in one high-voltage battery pack depending on a predetermined period for monitoring the high-voltage battery pack, wherein the high-voltage battery controllers are configured to transition state of the plurality of high-voltage battery controllers together to an end state when a high-voltage battery controller among the high-voltage battery controllers, which has completed a monitoring operation, first waits until all monitoring operations of the high-voltage battery controllers that have not yet completed monitoring operations are completed and then all the monitoring operations of the high-voltage battery controllers are completed.

Abstract: A method for manufacturing a semiconductor device and a semiconductor device produced thereby. For example and without limitation, various aspects of this disclosure provide methods for manufacturing a semiconductor device, and semiconductor devices produced thereby, that comprise forming an interposer including a reinforcement layer.

Abstract: An electronic apparatus includes: an electronic module; a display panel disposed on the electronic module and including a first display region and a second display region adjacent to the first display region, the second display region overlapping the electronic module; and a polarization plate disposed on the display panel and including a first polarization region overlapping the first display region and a second polarization region including a polarization part and a non-polarization part having higher light transmittance than the polarization part, the non-polarization part overlapping the second display region.