Patents by Inventor Inbal Binsky

Inbal Binsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti CD84 antibodies, compositions comprising same and uses thereof
    Patent number: 10611839
    Abstract: An isolated antibody comprising an antigen recognition domain which specifically binds CD84 and (i) down regulates the anti-apoptotic activity of stromal cells on chronic lymphocytic leukemia (CLL) cells; and/or (ii) induces mobilization of CLL cells from the bone marrow. Also provided are antibodies comprising antigen recognition domains comprising complementarity determining regions as indicated and uses thereof.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: April 7, 2020
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Idit Shachar, Inbal Binsky, Ayelet Marom
  • COMPOSITIONS COMPRISING SOLUBLE CD84 OR ANTI-CD84 ANTIBODIES AND METHODS FOR DIAGNOSING AND TREATING B-CLL
    Publication number: 20190359708
    Abstract: A method of diagnosing B-CLL in a subject in need thereof is provided. The method comprising determining in a biological sample of the subject a level of CD84 isoform C (SEQ ID NO: 30), wherein an increase in the level of the CD84 isoform C (SEQ ID NO: 30) beyond a predetermined threshold with respect to a level of the CD84 in a biological sample from a healthy individual is indicative of the B-CLL.
    Type: Application
    Filed: June 4, 2019
    Publication date: November 28, 2019
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Idit SHACHAR, Inbal BINSKY, Mirko SOBOTTA
  • Compositions comprising soluble CD84 or anti-CD84 antibodies and methods for diagnosing and treating B-CLL
    Patent number: 10329347
    Abstract: A method of diagnosing B-CLL in a subject in need thereof is provided. The method comprising determining in a biological sample of the subject a level of CD84 isoform C (SEQ ID NO: 30), wherein an increase in the level of the CD84 isoform C (SEQ ID NO: 30) beyond a predetermined threshold with respect to a level of the CD84 in a biological sample from a healthy individual is indicative of the B-CLL.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: June 25, 2019
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Idit Shachar, Inbal Binsky, Mirko Sobotta
  • ANTI CD84 ANTIBODIES, COMPOSITIONS COMPRISING SAME AND USES THEREOF
    Publication number: 20180327493
    Abstract: An isolated antibody comprising an antigen recognition domain which specifically binds CD84 and (i) down regulates the anti-apoptotic activity of stromal cells on chronic lymphocytic leukemia (CLL) cells; and/or (ii) induces mobilization of CLL cells from the bone marrow. Also provided are antibodies comprising antigen recognition domains comprising complementarity determining regions as indicated and uses thereof.
    Type: Application
    Filed: July 30, 2018
    Publication date: November 15, 2018
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Idit SHACHAR, Inbal BINSKY, Ayelet MAROM
  • Anti CD84 antibodies, compositions comprising same and uses thereof
    Patent number: 10066014
    Abstract: An isolated antibody comprising an antigen recognition domain which specifically binds CD84 and (i) down regulates the anti-apoptotic activity of stromal cells on chronic lymphocytic leukemia (CLL) cells; and/or (ii) induces mobilization of CLL cells from the bone marrow. Also provided are antibodies comprising antigen recognition domains comprising complementarity determining regions as indicated and uses thereof.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: September 4, 2018
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Idit Shachar, Inbal Binsky, Ayelet Marom
  • ANTI CD84 ANTIBODIES, COMPOSITIONS COMPRISING SAME AND USES THEREOF
    Publication number: 20170260270
    Abstract: An isolated antibody comprising an antigen recognition domain which specifically binds CD84 and (i) down regulates the anti-apoptotic activity of stromal cells on chronic lymphocytic leukemia (CLL) cells; and/or (ii) induces mobilization of CLL cells from the bone marrow. Also provided are antibodies comprising antigen recognition domains comprising complementarity determining regions as indicated and uses thereof.
    Type: Application
    Filed: February 5, 2015
    Publication date: September 14, 2017
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Idit SHACHAR, Inbal BINSKY, Ayelet MAROM
  • COMPOSITIONS COMPRISING SOLUBLE CD84 OR ANTI-CD84 ANTIBODIES AND METHODS FOR DIAGNOSING AND TREATING B-CLL
    Publication number: 20150344972
    Abstract: A method of diagnosing B-CLL in a subject in need thereof is provided. The method comprising determining in a biological sample of the subject a level of CD84 isoform C (SEQ ID NO: 30), wherein an increase in the level of the CD84 isoform C (SEQ ID NO: 30) beyond a predetermined threshold with respect to a level of the CD84 in a biological sample from a healthy individual is indicative of the B-CLL.
    Type: Application
    Filed: August 17, 2015
    Publication date: December 3, 2015
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Idit SHACHAR, Inbal BINSKY, Mirko SOBOTTA
  • Compositions comprising soluble CD84 or anti-CD84 antibodies and methods for diagnosing and treating B-CLL
    Patent number: 9109029
    Abstract: A method of diagnosing B-CLL in a subject in need thereof is provided. The method comprising determining in a biological sample of the subject a level of CD84 isoform C (SEQ ID NO: 30), wherein an increase in the level of the CD84 isoform C (SEQ ID NO: 30) beyond a predetermined threshold with respect to a level of the CD84 in a biological sample from a healthy individual is indicative of the B-CLL.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: August 18, 2015
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Idit Shachar, Inbal Binsky, Mirko Sobotta
  • COMPOSITIONS COMPRISING SOLUBLE CD84 OR ANTI-CD84 ANTIBODIES AND METHODS FOR DIAGNOSING AND TREATING B-CLL
    Publication number: 20140147451
    Abstract: A method of diagnosing B-CLL in a subject in need thereof is provided. The method comprising determining in a biological sample of the subject a level of CD84 isoform C (SEQ ID NO: 30), wherein an increase in the level of the CD84 isoform C (SEQ ID NO: 30) beyond a predetermined threshold with respect to a level of the CD84 in a biological sample from a healthy individual is indicative of the B-CLL.
    Type: Application
    Filed: February 5, 2014
    Publication date: May 29, 2014
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Idit SHACHAR, Inbal Binsky, Mirko Sobotta
  • Compositions comprising soluble CD84 or anti-CD84 antibodies and methods for diagnosing and treating B-CLL
    Patent number: 8686121
    Abstract: A method of diagnosing B-CLL in a subject in need thereof is provided. The method comprising determining in a biological sample of the subject a level of CD84 isoform C (SEQ ID NO: 30), wherein an increase in the level of the CD84 isoform C (SEQ ID NO: 30) beyond a predetermined threshold with respect to a level of the CD84 in a biological sample from a healthy individual is indicative of the B-CLL.
    Type: Grant
    Filed: September 23, 2009
    Date of Patent: April 1, 2014
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Idit Shachar, Inbal Binsky, Mirko Sobotta
  • COMPOSITIONS COMPRISING SOLUBLE CD84 OR ANTI-CD84 ANTIBODIES AND METHODS FOR DIAGNOSING AND TREATING B-CLL
    Publication number: 20110189202
    Abstract: A method of diagnosing B-CLL in a subject in need thereof is provided. The method comprising determining in a biological sample of the subject a level of CD84 isoform C (SEQ ID NO: 30), wherein an increase in the level of the CD84 isoform C (SEQ ID NO: 30) beyond a predetermined threshold with respect to a level of the CD84 in a biological sample from a healthy individual is indicative of the B-CLL.
    Type: Application
    Filed: September 23, 2009
    Publication date: August 4, 2011
    Applicant: Yeda Research And Development Co., Ltd.
    Inventors: Idit Shachar, Inbal Binsky, Mirko Sobotta