Patents by Inventor Inbal VAKNIN

Inbal VAKNIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-PVRIG ANTIBODIES FORMULATIONS AND USES THEREOF
    Publication number: 20240082397
    Abstract: The present invention is directed to anti-PVRIG antibodies and stable liquid pharmaceutical formulations thereof. The present invention is directed to monotherapy and combination treatments with anti-PVRIG antibodies and anti-PD-1 antibodies, in particular nivolumab, using stable liquid pharmaceutical formulations thereof.
    Type: Application
    Filed: January 28, 2022
    Publication date: March 14, 2024
    Inventors: Mark WHITE, Inbal BARBIRO, Ilan VAKNIN, Assaf WOOL, Zurit LEVINE, Henry Adeboye ADEWOYE, MD, Michael BUCKLEY, Jun LU, John HUNTER, Anat COHEN-DAYAG, Gad S. COJOCARU, Eran OPHIR, Zoya ALTEBER
  • COMBINATION THERAPY WITH ANTI-PVRIG ANTIBODIES FORMULATIONS AND ANTI-PD-1 ANTIBODIES
    Publication number: 20240076373
    Abstract: The present invention is directed to anti-PVRIG antibodies and stable liquid pharmaceutical formulations thereof. The present invention is directed to monotherapy and combination treatments with anti-PVRIG antibodies and anti-PD-1 antibodies, in particular nivolumab, using stable liquid pharmaceutical formulations thereof. The present invention also provides biomarkers for use in determining populations for treatment with anti-PVRIG antibodies and such biomarkers include, for example PVRIG and/or PVRL2 expression.
    Type: Application
    Filed: January 28, 2022
    Publication date: March 7, 2024
    Inventors: Inbal BARBIRO, Ilan VAKNIN, Assaf WOOL, Zurit LEVINE, Paul A. BASCIANO, Brian D. LAMON, Henry Adeboye ADEWOYE, John HUNTER, Anat COHEN-DAYAG, Gad S. COJOCARU, Eran OPHIR, Zoya ALTEBER
  • Composition and method for treating androgen-dependent disorders
    Patent number: 10240132
    Abstract: Chimeric polypeptides comprising a dihydrotestosterone (DHT) reductase moiety, such as 3 alpha-hydroxysteroid dehydrogenase (3?-HSD), fused to a signal peptide moiety, polynucleotides encoding same, and compositions comprising at least one microorganism cell capable of secreting the chimeric polypeptide, are provided. Further provided are methods and kits for treating, preventing or ameliorating androgen-dependent disorders, including but not limited to androgenic alopecia.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: March 26, 2019
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.
    Inventors: Roee Amit, Alexey Tomsov, Orna Atar, Liron Abrahami, Yael Annis, Roni Cohen, Alexandra Ereskovsky, Noa Katz, Lior Levy, Maayan Lufton, Tal Ofek, Sagi Sheinkman, Nitzan Shmuel, Inbal Vaknin, Ruth Veksler, Adi Yannai
  • COMPOSITION AND METHOD FOR TREATING ANDROGEN-DEPENDENT DISORDERS
    Publication number: 20170275596
    Abstract: Chimeric polypeptides comprising a dihydrotestosterone (DHT) reductase moiety, such as 3 alpha-hydroxysteroid dehydrogenase (3?-HSD), fused to a signal peptide moiety, polynucleotides encoding same, and compositions comprising at least one microorganism cell capable of secreting the chimeric polypeptide, are provided. Further provided are methods and kits for treating, preventing or ameliorating androgen-dependent disorders, including but not limited to androgenic alopecia.
    Type: Application
    Filed: March 28, 2017
    Publication date: September 28, 2017
    Inventors: Roee AMIT, Alexey TOMSOV, Orna ATAR, Liron ABRAHAMI, Yael ANNIS, Roni COHEN, Alexandra ERESKOVSKY, Noa KATZ, Lior LEVY, Maayan LUFTON, Tal OFEK, Sagi SHEINKMAN, Nitzan SHMUEL, Inbal VAKNIN, Ruth VEKSLER, Adi YANNAI