Patents by Inventor Indra Kumar SIGIREDDI

Indra Kumar SIGIREDDI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A METHOD OF IMPROVING STABILITY OF IMMUNE CHECK POINT INHIBITORS
    Publication number: 20240368284
    Abstract: The present invention relates to pharmaceutical formulations of antibodies and antigen-binding fragments against human programmed death receptor-1 (PD-1)/programmed death receptor Ligand 1 (PD-L1), and method for preparing the same. The disclosed formulations stabilizes anti-PD1/anti-PD L1 antibody from lower to higher concentrations rendering it suitable for different modes of administration (subcutaneous/intravenous).
    Type: Application
    Filed: September 2, 2022
    Publication date: November 7, 2024
    Inventors: Murali JAYARAMAN, Saisharan K GOUD, Sunil ASHOK NANKAR, Maya NANATH, Indra Kumar SIGIREDDI, Lovisha AGGARWAL, Sireesha Goswamy KALIGATLA, Ravi Kumar MARIKANTY, Abirami S, Giridhar SIVALANKA, Ravi Kiranmai PENMETSA, Suman LABALA, Mahesh INGALE, Puja SARKAR, Mayur Vijay DESAI, Prathibha Chandrashekhar KIRAVE, Chetan Govindrao SHINDE
  • FORMULATIONS OF IMMUNE CHECK POINT INHIBITORS OR LIKE
    Publication number: 20240366757
    Abstract: The present invention discloses a stable buffer free formulation of anti-PD1/anti-PD-L1 antibody, comprising an anti-PD1 or an anti-PD-L1 antibody, water, mannitol and surfactant, and stabilized at a pH of about 5.0-about 6.0. The disclosed antibody formulation is a liquid formulation and can be lyophilized. Further, the said formulation is also suitable for different mode of administration such as subcutaneous/intravenous, for therapeutic use.
    Type: Application
    Filed: September 7, 2022
    Publication date: November 7, 2024
    Inventors: Murali JAYARAMAN, Saisharan K GOUD, Sunil Ashok NANKAR, Indra Kumar SIGIREDDI, Suman LABALA, Giridhar Purushottam TALABATTULA, Lalithkumar BASKARAN, Shalaka R