Patents by Inventor Indrajit Sanyal
Indrajit Sanyal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9505823Abstract: Disclosed are fusion proteins that include albumin fused to a polypeptide that has insulin activity. The fusion proteins may include albumin fused to insulin or an insulin analog. In particular, the fusions proteins may include albumin fused to a single chain insulin analog. The fusion proteins may exhibit extended insulin activity in vivo or in vitro relative to insulin that is not fused to albumin. The fusion proteins may be formulated as aerosol compositions.Type: GrantFiled: August 7, 2007Date of Patent: November 29, 2016Assignee: TEV A Biopharmaceuticals USA, Inc.Inventors: Adam C. Bell, Craig A. Rosen, Indrajit Sanyal, Qinghai Zhao
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Publication number: 20080057004Abstract: Disclosed are fusion proteins that include albumin fused to a polypeptide that has insulin activity. The fusion proteins may include albumin fused to insulin or an insulin analog. In particular, the fusions proteins may include albumin fused to a single chain insulin analog. The fusion proteins may exhibit extended insulin activity in vivo or in vitro relative to insulin that is not fused to albumin. The fusion proteins may be formulated as aerosol compositions.Type: ApplicationFiled: August 7, 2007Publication date: March 6, 2008Inventors: Adam Bell, Craig Rosen, Indrajit Sanyal, Qinghai Zhao
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Publication number: 20070253973Abstract: The invention relates generally to fusion proteins comprising at least one therapeutic protein or vaccine antigen and alpha fetoprotein. The therapeutic protein or vaccine antigen can be, for example, a peptide, antibody, fragment thereof, or variant thereof. The therapeutic protein or vaccine antigen is fused to alpha-fetoprotein, an alpha-fetoprotein fragment, or an alpha-fetoprotein variant. Also encompassed by the invention are nucleic acids encoding the fusion proteins of the invention, vectors comprising such nucleic acids, and host cells transformed with such nucleic acids and/or vectors. Methods of making and using the fusion proteins, nucleic acids, vectors, and host cells are also encompassed by the invention.Type: ApplicationFiled: March 7, 2007Publication date: November 1, 2007Inventors: Craig Rosen, Adam Bell, Indrajit Sanyal
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Publication number: 20050202494Abstract: The invention relates to catalases and to polynucleotides encoding the catalases. In addition methods of designing new catalases and method of use thereof are also provided. The catalases have increased activity and stability at increased pH and temperature.Type: ApplicationFiled: April 1, 2005Publication date: September 15, 2005Inventors: Jay Short, Dan Robertson, Indrajit Sanyal, Robert Adhikari, Eric Mathur
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Patent number: 6900033Abstract: Binding polypeptides comprising specific amino acid sequences are disclosed that specifically bind ACE-2 protein or ACE-2-like polypeptides. The binding polypeptides can be used in methods of the invention for detecting, isolating, or purifying ACE-2 protein or ACE-2-like polypeptides in solutions or mixtures, or biological samples. The invention also relates to nucleic acid molecules encoding these ACE-2 binding polypeptides, vectors and host cells containing these nucleic acids, and methods for producing the same. The present invention also relates to methods and compositions for detecting, diagnosing, prognosing, preventing, treating or ameliorating a disease or disorder associated with aberrant ACE-2 or ACE-2 receptor expression or inappropriate function of ACE-2 or ACE-2 receptor, comprising use of ACE-2 binding polypeptides or fragments or variants thereof, that specifically bind to ACE-2.Type: GrantFiled: June 3, 2002Date of Patent: May 31, 2005Assignee: Human Genome Sciences, Inc.Inventors: Tom J. Parry, Les Sekut, Craig A. Rosen, Vivian R. Albert, Indrajit Sanyal, Lili Huang, Charles R. Wescott
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Publication number: 20040121429Abstract: Binding polypeptides comprising specific amino acid sequences are disclosed that specifically bind ACE-2 protein or ACE-2-like polypeptides. The binding polypeptides can be used in methods of the invention for detecting, isolating, or purifying ACE-2 protein or ACE-2-like polypeptides in solutions or mixtures, or biological samples. The invention also relates to nucleic acid molecules encoding these ACE-2 binding polypeptides, vectors and host cells containing these nucleic acids, and methods for producing the same. The present invention also relates to methods and compositions for detecting, diagnosing, prognosing, preventing, treating or ameliorating a disease or disorder associated with aberrant ACE-2 or ACE-2 receptor expression or inappropriate function of ACE-2 or ACE-2 receptor, comprising use of ACE-2 binding polypeptides or fragments or variants thereof, that specifically bind to ACE-2.Type: ApplicationFiled: June 3, 2002Publication date: June 24, 2004Inventors: Tom J. Parry, Les Sekut, Craig A. Rosen, Vivian R. Albert, Indrajit Sanyal, Lili Huang, Charles R. Wescott
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Publication number: 20040005655Abstract: Catalase enzymes derived from bacterial from the genera Alcaligenese (Deleya) and Microscilla are disclosed. The enzymes are produced from native or recombinant host cells and can be utilized to destroy or detect hydrogen peroxide, e.g., in production of glyoxylic acid and in glucose sensors, and in processes where hydrogen peroxide is used as a bleaching or antibacterial agent, e.g. in contact lens cleaning, in bleaching steps in pulp and paper preparation and in the pasteurization of dairy products.Type: ApplicationFiled: August 2, 2001Publication date: January 8, 2004Applicant: Diversa CorporationInventors: Dan E. Robertson, Indrajit Sanyal, Robert S. Adhikary
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Publication number: 20030138894Abstract: Binding polypeptides comprising specific amino acid sequences are disclosed that specifically bind ACE-2 protein or ACE-2-like polypeptides. The binding polypeptides can be used in methods of the invention for detecting, isolating, or purifying ACE-2 protein or ACE-2-like polypeptides in solutions or mixtures, or biological samples. The invention also relates to nucleic acid molecules encoding these ACE-2 binding polypeptides, vectors and host cells containing these nucleic acids, and methods for producing the same. The present invention also relates to methods and compositions for detecting, diagnosing, prognosing, preventing, treating or ameliorating a disease or disorder associated with aberrant ACE-2 or ACE-2 receptor expression or inappropriate function of ACE-2 or ACE-2 receptor, comprising use of ACE-2 binding polypeptides or fragments or variants thereof, that specifically bind to ACE-2.Type: ApplicationFiled: June 3, 2002Publication date: July 24, 2003Inventors: Tom J. Parry, Les Sekut, Craig A. Rosen, Vivian R. Albert, Indrajit Sanyal, Lili Huang, Charles R. Wescott
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Publication number: 20020102680Abstract: The invention relates to catalases and to polynucleotides encoding the catalases. In addition methods of designing new catalases and method of use thereof are also provided. The catalases have increased activity and stability at increased pH and temperature.Type: ApplicationFiled: June 19, 2001Publication date: August 1, 2002Inventors: Dan E. Robertson, Indrajit Sanyal, Robert Adhikari
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Patent number: 6410290Abstract: Catalase enzymes derived from bacteria from the genera Alcaligenes (Deleya) and Microscilla are disclosed. The enzymes are produced from native or recombinant host cells and can be utilized to destroy or detect hydrogen peroxide, e.g., in production of glyoxylic acid and in glucose sensors, and in processes where hydrogen peroxide is used as a bleaching or antibacterial agent, e.g. in contact lens cleaning, in bleaching steps in pulp and paper preparation and in the pasteurization of dairy products.Type: GrantFiled: October 5, 1999Date of Patent: June 25, 2002Assignee: Diversa CorporationInventors: Dan E. Robertson, Indrajit Sanyal, Robert S. Adhikary
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Patent number: 6074860Abstract: Catalase enzymes derived from bacteria from the genera Alcaligenes (Deleya) and Microscilla are disclosed. The enzymes are produced from native or recombinant host cells and can be utilized to destroy or detect hydrogen peroxide, e.g., in production of glyoxylic acid and in glucose sensors, and in processes where hydrogen peroxide is used as a bleaching or antibacterial agent, e.g. in contact lens cleaning, in bleaching steps in pulp and paper preparation and in the pasteurization of dairy products.Type: GrantFiled: October 16, 1997Date of Patent: June 13, 2000Assignee: Diversa CorporationInventors: Dan E. Robertson, Indrajit Sanyal, Robert S. Adhikary
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Patent number: 5939300Abstract: Catalase enzymes derived from bacteria from the genera Alcaligenes (Deleya) and Microscilla are disclosed. The enzymes are produced from native or recombinant host cells and can be utilized to destroy or detect hydrogen peroxide, e.g., in production of glyoxylic acid and in glucose sensors, and in processes where hydrogen peroxide is used as a bleaching or antibacterial agent, e.g. in contact lens cleaning, in bleaching steps in pulp and paper preparation and in the pasteurization of dairy products.Type: GrantFiled: July 3, 1996Date of Patent: August 17, 1999Assignee: Diversa CorporationInventors: Dan E. Robertson, Indrajit Sanyal, Robert S. Adhikary