Patents by Inventor Indu R. Ramachandran

Indu R. Ramachandran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITION OF THE SH2-DOMAIN CONTAINING PROTEIN TYR-PHOSPHATASE, SHP-1, TO ENHANCE VACCINES
    Publication number: 20090123501
    Abstract: The invention describes the use of dendritic cell vaccines, wherein SHP-1 expression or activity is modulated in the dendritic cell. In particular, the invention provides dendritic cells (DC) transduced with an SHP1-shRNA adenovirus, or dominant negative (dn-SHP-1) or constitutively active (ca-SHP-1), and pulsed with an antigen. The methods and compositions of the invention are used for the prevention and/or treatment of cancers, other cell proliferation diseases and conditions, diseases caused by a pathogen, or autoimmune disorders.
    Type: Application
    Filed: May 16, 2008
    Publication date: May 14, 2009
    Applicant: Baylor College of Medicine
    Inventors: Jonathan Levitt, Indu R. Ramachandran, Kevin M. Slawin