Patents by Inventor Ine Lentacker

Ine Lentacker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic nanoparticles and methods of use thereof
    Patent number: 12642868
    Abstract: The present invention relates to a method and composition for optimized intracellular delivery of nucleic acids, in particular mRNA. In addition to mRNA, the composition, in particular a nanoparticle, may include a glycolipid antigen. Combinations with checkpoint inhibitors are also provided. The method and composition of the invention targets antigen presenting cells and is especially useful for immunotherapy and vaccination purposes.
    Type: Grant
    Filed: September 17, 2019
    Date of Patent: June 2, 2026
    Assignee: UNIVERSITEIT GENT
    Inventors: Stefaan De Smedt, Rein Verbeke, Heleen Dewitte, Ine Lentacker
  • PREVENTION AND TREATMENT OF INFECTIONS WITH INTRACELLULAR BACTERIA
    Publication number: 20250281588
    Abstract: The present invention relates to a method and composition for prevention and treatment of infections in a subject, in particular, with intracellular bacteria. The invention provides an optimized intracellular delivery of an active agent, in particular, a nucleic acid, using a nanoparticle formulation including an iNKT cell agonist.
    Type: Application
    Filed: April 27, 2023
    Publication date: September 11, 2025
    Inventors: Rein Verbeke, Ine Lentacker, llke Aernout, Stefaan De Smedt
  • THERAPEUTIC NANOPARTICLES AND METHODS OF USE THEREOF
    Publication number: 20210369862
    Abstract: The present invention relates to a method and composition for optimized intracellular delivery of nucleic acids, in particular mRNA. In addition to mRNA, the composition, in particular a nanoparticle, may include a glycolipid antigen. Combinations with checkpoint inhibitors are also provided. The method and composition of the invention targets antigen presenting cells and is especially useful for immunotherapy and vaccination purposes.
    Type: Application
    Filed: September 17, 2019
    Publication date: December 2, 2021
    Applicant: Universiteit Gent
    Inventors: Stefaan De Smedt, Rein Verbeke, Heleen Dewitte, Ine Lentacker