Patents by Inventor Inese Smukste

Inese Smukste has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MITOCHONDRIA-TARGETING PEPTIDES
    Publication number: 20240059734
    Abstract: Disclosed are non-natural peptides useful for the treatment and prevention of ischemia-reperfusion injury (e.g., cardiac ischemia-reperfusion injury) or myocardial infarction.
    Type: Application
    Filed: July 12, 2023
    Publication date: February 22, 2024
    Inventors: Guozhu Zheng, Mark J. Bamberger, Inese Smukste
  • Mitochondria-targeting peptides
    Patent number: 11795196
    Abstract: Disclosed are non-natural peptides useful for the treatment and prevention of ischemia-reperfusion injury (e.g., cardiac ischemia-reperfusion injury) or myocardial infarction.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: October 24, 2023
    Assignee: Stealth BioTherapeutics Inc.
    Inventors: Guozhu Zheng, Mark J. Bamberger, Inese Smukste
  • MITOCHONDRIA-TARGETING PEPTIDES
    Publication number: 20230146515
    Abstract: Disclosed are non-natural peptides useful for the treatment and prevention of ischemia-reperfusion injury (e.g., cardiac ischemia-reperfusion injury) or myocardial infarction.
    Type: Application
    Filed: December 14, 2018
    Publication date: May 11, 2023
    Inventors: Guozhu Zheng, Mark J. Bamberger, Inese Smukste
  • MITOCHONDRIA-TARGETING PEPTIDES
    Publication number: 20220041653
    Abstract: Disclosed are analogs of SBT-20. The compounds are useful for the treatment and prevention of ischemia-reperfusion injury (e.g., cardiac ischemia-reperfusion injury) or myocardial infarction.
    Type: Application
    Filed: November 19, 2019
    Publication date: February 10, 2022
    Inventors: Guozhu Zheng, Mark J. Bamberger, Inese Smukste
  • ANALOGS THAT TARGET MITOCHONDRIAL DISEASES
    Publication number: 20220041654
    Abstract: Disclosed are analogs of elamipretide (MTP-131). The compounds are useful for the treatment and prevention of ischemia-reperfusion injury (e.g., cardiac ischemia-reperfusion injury) or myocardial infarction.
    Type: Application
    Filed: November 19, 2019
    Publication date: February 10, 2022
    Inventors: Guozhu Zheng, Mark J. Bamberger, Inese Smukste
  • IDENTIFICATION OF ANTI-CANCER COMPOUNDS AND COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE AND METHODS OF TREATMENT THEREOF
    Publication number: 20100022637
    Abstract: Small molecule screening via high-throughput screening (HTS) methods was employed to identify compounds useful for treating or preventing cancer (such as compounds that enable cells to overcome E6-oncoprotein-mediated drug resistance) or neurodegenerative disorders (such as Huntington's disease, HD). Compounds were identified that potentiate the lethality of anti-tumor agents as well as rescue a disease-state lethality. These compounds are acylated secondary amines referred to herein as indoxins and revertins.
    Type: Application
    Filed: September 29, 2006
    Publication date: January 28, 2010
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Brent R. Stockwell, Inese Smukste