Patents by Inventor Inge Vliegen

Inge Vliegen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL INHIBITORS OF FLAVIVIRUS REPLICATION
    Publication number: 20110224208
    Abstract: The present invention relates to a series of Isoquinolone derivatives which are suitable to treat infections with viruses belonging to the family of the Flaviviridae and more preferably infections with Hepatitis C virus (HCV). The present invention also relates to Isoquinolone compounds for use as a medicine for the prevention or treatment of viral infections, preferably infections with viruses belonging to the family of the Flaviviridae.
    Type: Application
    Filed: November 16, 2009
    Publication date: September 15, 2011
    Applicant: KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D
    Inventors: Dorothée Bardiot, Emilie Blanche, Patrick Chaltin, Mohamed Koukni, Pieter Leyssen, Johan Neyts, Arnaud Marchand, Inge Vliegen
  • Drug-resistant mutants of hepatitis C virus
    Publication number: 20070128625
    Abstract: The present invention provides nucleotides, peptides, HCV mutants, and cell lines containing mutations associated with drug resistance. In addition, the present invention provides methods for screening for therapeutic compounds capable of inhibiting HCV as well as methods for inhibiting HCV, e.g., by targeting specific binding sites associated with HCV drug resistance.
    Type: Application
    Filed: July 24, 2006
    Publication date: June 7, 2007
    Inventors: Nina Boddeker, Johan Neyts, I-Hung Shih, Inge Vliegen, Weidong Zhong